Results 51 to 60 of about 799,277 (314)

DataSheet_1_Performance of spectral flow cytometry and mass cytometry for the study of innate myeloid cell populations.docx [PDF]

open access: yes, 2023
IntroductionMonitoring of innate myeloid cells (IMC) is broadly applied in basic and translational research, as well as in diagnostic patient care.
Kassem, Sara   +25 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Flow cytometric analysis of the oxidative status in human peripheral blood mononuclear cells of workers exposed to welding fumes [PDF]

open access: yes, 2010
Flow cytometry is a simple analytical technique that identifies, counts, and characterizes cells. The oxidative status of cells is influenced by many exogenous sources, such as occupational exposure to welding fumes.
Du Plessis, Lissinda   +13 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Human Neutrophil Antigen Genotype and Allele Frequencies in Iranian Blood Donors

open access: yesJournal of Immunology Research, 2022
Objective. Human neutrophil antigens (HNAs) can be targeted by HNA-allo antibodies and cause a variety of clinical conditions such as transfusion-related acute lung injury (TRALI) and neonatal alloimmune neutropenia (NAIN).
Behnaz Esmaeili   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Seven-year study of viability and absolute counts in cord blood units by flow cytometry in Greece

open access: yesInternational Journal of Hematology-Oncology and Stem Cell Research, 2015
#No Abstract#
Vasiliki E-Kalodimou   +2 more
doaj  

Unravelling Plasma Extracellular Vesicle Diversity With Optimised Spectral Flow Cytometry

open access: yesJournal of Extracellular Biology
Extracellular vesicles (EVs) are crucial for intercellular communication and are found in various biological fluids. The identification and immunophenotyping of such small particles continue to pose significant challenges.
Daniela Boselli   +10 more
doaj   +1 more source

Spectral Flow Cytometry [PDF]

open access: yesCurrent Protocols in Cytometry, 2013
AbstractInterest in measuring the complete fluorescence spectra of individual cells in flow can be traced to the earliest days of flow cytometry. Recent advances in detectors, optics, and computation have made it possible to make full spectral measurements in the sub‐millisecond time frame in which flow cytometry measurements typically occur.
John P, Nolan, Danilo, Condello
openaire   +2 more sources

Analysis of Nucleocytoplasmic Protein Shuttling by Imaging Flow Cytometry [PDF]

open access: yes, 2015
Many intracellular signal transduction events involve the reversible shuttling of proteins between the cytoplasm and the nucleus. Study of these processes requires imaging information on the protein localization in a given cell and a large number of ...
Elizaveta Fasler-Kan   +7 more
core   +1 more source

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