Results 61 to 70 of about 5,519,742 (398)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation. [PDF]

open access: yes, 2018
Both adjuvants and focal ablation can alter the local innate immune system and trigger a highly effective systemic response. Our goal is to determine the impact of these treatments on directly treated and distant disease and the mechanisms for the ...
Borowsky, Alexander D   +13 more
core   +1 more source

Evaluation of CD38 expression in Sudanese patients with chronic lymphocytic leukemia

open access: yesBMC Research Notes, 2018
Objective The objective of this study was to evaluate the cluster of differentiation-38 (CD38) expression in Sudanese patients with chronic lymphocytic leukemia (CLL) and to determine its association with clinical and laboratory characteristics of the ...
Enaam Abdelrhman Abdelgader   +6 more
doaj   +1 more source

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

open access: yesEuropean Journal of Immunology, 2019
These guidelines are a consensus work of a considerable number of members of the immunology and flow cytometry community. They provide the theory and key practical aspects of flow cytometry enabling immunologists to avoid the common errors that often ...
Andrea Cossarizza   +435 more
semanticscholar   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy. [PDF]

open access: yes, 2019
The success of immunotherapy has led to a myriad of clinical trials accompanied by efforts to gain mechanistic insight and identify predictive signatures for personalization.
Amir, El-Ad D   +13 more
core   +3 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Evidence of unreduced gamete production from interspecific crosses between Gossypium hirsutum and G. herbaceum [PDF]

open access: yes, 2009
In order to analyze the gene flow between the allotetraploid cultivated cotton (Gossypium hirsutum, AADD, 2n=52) and the wild diploid (G. herbaceum, AA, 2n=26), the possibility of natural hybridization between these two cotton species has been ...
Chèvre, Anne-Marie   +7 more
core  

UVB radiation induced effects on cells studied by FTIR spectroscopy

open access: yes, 2010
We have made a preliminary analysis of the results about the eVects on tumoral cell line (lymphoid T cell line Jurkat) induced by UVB radiation (dose of 310 mJ/cm^2) with and without a vegetable mixture. In the present study, we have used two techniques:
A. Congiu Castellano   +21 more
core   +1 more source

Flowcytometric assessment of fetomaternal hemorrhage during external cephalic version at term [PDF]

open access: yes, 2008
External cephalic version (ECV) at term is a safe procedure and reduces the incidence of cesarean sections for breech presentation. One of the known complications, however, is an ECV-related disruption of the placental barrier and a subsequent ...
Friese, Klaus   +6 more
core   +2 more sources

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