Results 111 to 120 of about 2,192,114 (314)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Modified Ricci flow on a principal bundle
, 2008 textLet M be a Riemannian manifold with metric g, and let P be a principal G-bundle over M having connection one-form a. One can define a modified version of the Ricci flow on P by fixing the size of the fiber.
Young, Andrea Nicole, 1979-
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Overland flow resistance & flood generation in semi-arid environments: explaining the restrained draining of the rain in Spain [PDF]
, 2009 Resistance equations developed for pipe flows and open channel flows cannot be applied to model overland flows uncritically. The formulation of these equations employs several assumptions that are specific to the conditions in which they were developed ...
Smith, Mark William
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Statistical models for over-dispersion in the frequency of peaks over threshold data for a flow series. [PDF]
, 2010 In a peaks over threshold analysis of a series of river flows, a sufficiently high threshold is used to extract the peaks of independent flood events. This paper reviews existing, and proposes new, statistical models for both the annual counts of such ...
Tawn, Jonathan A. +3 more
core +1 more source
AIP AdvancesThe objective of this research is to combine Artificial Neural Networks (ANNs) and Computational Fluid Dynamics (CFD) approaches to leverage the advantages of both methods.
Atif Asghar +4 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
, 2007 The near and far pressure fields of three-dimensional turbulent cavity flow are studied by time-accurate simulations coupled with aeroacoustic predictions.
Zhang, Xin +5 more
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FLOW OVER TIME PROBLEM WITH INFLOW-DEPENDENT TRANSIT TIMES
Journal of Institute of Science and Technology, 2018 Network flow over time is an important area for the researcher relating to the traffic assignment problem. Transmission times of the vehicles directly depend on the number of vehicles entering the road. Flow over time with fixed transit times can be solved by using classical (static) flow algorithms in a corresponding time expanded network which is ...
Tanka Nath Dhamala +2 more
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The sedimentology and dynamics of mega-dunes, Jamuna river, Bangladesh [PDF]
, 1998 This thesis quantifies the occurrence, morphology and flow dynamics of dune bcdforms in the main rivers of Bangladesh: the Jamuna, Meghna and Ganges. Field work was conducted as part of the River Survey Project (Bangladesh Flood Action Plan 24) between ...
Roden, Julie Elizabeth
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