Results 121 to 130 of about 2,192,114 (314)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
TRPIV investigation of space-time correlation in turbulent flows over flat and wavy walls
, 2014 The present experimental work is devoted to investigate a new space-time correlation model for the turbulent boundary layer over a flat and a wavy walls.
Guan XL, Jiang N(姜楠), Wang W
core +1 more source
The relationship between ENSO and Paraná River flow [PDF]
Advances in Geosciences, 2006 Several studies indicate that there is a relationship between the climatic variability in the South American continent and alterations of the position and intensity of the heat sources in the equatorial region.
A. O. Cardoso, P. L. Silva Dias
doaj
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Data in BriefIn previous work, a Large Eddy Simulation turbulence (LES) algorithm was developed for finite element-based computational fluid dynamics, using a hybrid continuous-discontinuous Galerkin scheme. The test case for this was a backward-facing step, which is
Angus C.W. Creech, Adrian Jackson
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Advances in Mechanical Engineering, 2019 Recent progress in nanotechnology and nanoscience has attended the researchers’ interest due to its inspiring industrial and technological applications.
Sami Ullah Khan, Sabir Ali Shehzad
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Emitter clogging when using water from a tributary of the Bogota River in Colombia
Agronomía Colombiana, 2016 An experiment was conducted to study the behavior of three types of emitters used in Colombia under real-work conditions using water from the Neusa River, a tributary of the Bogota River.
Johana Almario-Narváez +2 more
doaj +1 more source