Results 111 to 120 of about 3,031,429 (300)

A hydrodynamic model of an outer hair cell [PDF]

open access: yes
On the model it is possible to measure the force and the force direction for each individual hair as a function of the flow direction and velocity. Measurements were made at the man flow velocity .01 m/s, which is equivalent to a flow velocity in the ...
Jacobson, B. O.
core   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Numerical Investigation of the Scale Effects on Flow Pattern Around Rectangular Bridge Piers Using Fluent Software

open access: yesعلوم آب و خاک, 2019
Flow pattern around the bridge piers includes water surface profile, velocity profile, shear velocity, shear stress distribution, etc. In this research, the effects of the base shape along with scale effects on the flow pattern around the rectangular ...
Z. Talebi, H. Arvanaghi
doaj  

A Review of Experiments and Modeling of Gas-Liquid Flow in Electrical Submersible Pumps

open access: yesEnergies, 2018
As the second most widely used artificial lift method in petroleum production (and first in produced amount), electrical submersible pump (ESP) maintains or increases flow rate by converting kinetic energy to hydraulic pressure of hydrocarbon fluids.
Jianjun Zhu, Hong-Quan Zhang
doaj   +1 more source

Modelling how curved active proteins and shear flow pattern cellular shape and motility. [PDF]

open access: yesFront Cell Dev Biol, 2023
Sadhukhan S, Penič S, Iglič A, Gov NS.
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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