Results 61 to 70 of about 1,040,830 (316)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2011 Unsteady flow of a thin film of a Newtonian fluid or a non-Newtonian power-law fluid with power-law index N driven by a constant shear stress applied at the free surface, on a plane inclined at an angle α to the horizontal, is considered.
Wilson, Stephen +5 more
core +1 more source
Flow Stress Behavior of 15%SiCP/8009 Aluminum Matrix Composite During Hot Compression Deformation
Journal of Aeronautical Materials, 2017 The flow stress behavior of 15%SiCP/8009 aluminum matrix composite at deformation temperature of 400-550 ℃ and strain rate of 0.001-1 s-1 was studied by hot compression testing on the Gleeble-3500 thermal-mechanical simulator.
WANG Yu +5 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Flow along a long thin cylinder [PDF]
, 2008 Two different approaches have been used to calculate turblent flow along a long thin culinder where the flow is aligned with the cylinder. A boundary-layer code is used to predict the mean flow for very long cylinders (length to ratio of up to O(106 ...
O. R. TUTTY, Tutty, O.R.
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Enhanced tensile plasticity of Zr based bulk metallic glasses by a stress induced large scale flow
, 2017 Tensile plasticity in a Zr-based bulk metallic glasses is achieved through a stress induced large-scale flow. The large-scale flow is activated in a complex stress field which is produced by introducing micro-pits array on specimen surfaces using a ...
Huan, Y (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech LNM, Beijing 100190, Peoples R China. +6 more
core +1 more source
The Effects of Prestrain and Subsequent Annealing on Tensile Properties of CP-Ti
Metals, 2017 The aim of the present work is to investigate the effects of prestrain and subsequent annealing on tensile properties of commercial pure titanium (CP-Ti).
Le Chang, Chang-Yu Zhou, Xiao-Hua He
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Experimental and numerical studies of the flow structure generated by a submerged sluice gate [PDF]
, 2010 Sluice gates are commonly used to control discharge and levels, and to monitor discharge. However discharge formulas perform poorly at large opening and large submergence.
Cassan, Ludovic, Belaud, Gilles
core