Results 81 to 90 of about 2,693,773 (355)

Rheological instability in a simple shear thickening model

, 2001
We study the strain response to steady imposed stress in a spatially homogeneous, scalar model for shear thickening, in which the local rate of yielding \Gamma(l) of mesoscopic `elastic elements' is not monotonic in the local strain l.
Ajdari, A., Cates, M. E., Head, D. A.
core   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

On the impact of capillarity for strength at the nanoscale

, 2017
The interior of nanoscale crystals experiences stress that compensates the capillary forces and that can be large, in the order of 1 GPa. Various studies have speculated on whether and how this surface-induced stress affects the stability and plasticity ...
Mameka, Nadiia, Markmann, Jürgen, Weissmüller, Jörg   +2 more
core   +2 more sources

Numerical computation of the domain of operation of an electrospray of a very viscous liquid [PDF]

, 2010
A numerical study is carried out of the injection of a very viscous liquid of small electrical conductivity at a constant flow rate through an orifice in a metallic plate under the action of an electric field.
Higuera Antón, Francisco
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Couette Flow of Two-Dimensional Foams

, 2010
We experimentally investigate flow of quasi two-dimensional disordered foams in Couette geometries, both for foams squeezed below a top plate and for freely floating foams. With the top-plate, the flows are strongly localized and rate dependent.
Aussillous P., B. P. Tighe, Dennin M., G. Katgert, Höhler R., Larson R. G., M. E. Möbius, M. van Hecke, Möbius M. E., Rodts S., Terriac E.   +10 more
core   +1 more source

Wall slip, shear banding, and instability in the flow of a triblock copolymer micellar solution [PDF]

, 2007
The shear flow of a triblock copolymer micellar solution (PEO--PPO--PEO Pluronic P84 in brine) is investigated using simultaneous rheological and velocity profile measurements in the concentric cylinder geometry.
Colin, A., Manneville, S., Schosseler, F., Waton, G.   +3 more
core   +6 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Effects of Quasi-Static Strain Rate and Temperature on the Microstructural Features of Post-Processed Microstructures of Laser Powder Bed Fusion Ti6Al4V Alloy

Applied Sciences
This study documents an investigation of the flow stress properties and microstructural features of Ti6Al4V (ELI) alloy produced using laser powder bed fusion (LPBF).
Amos Muiruri, Maina Maringa, Willie du Preez   +2 more
doaj   +1 more source