Results 71 to 80 of about 2,693,773 (355)

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Relaxation oscillations and negative strain rate sensitivity in the Portevin - Le Chatelier effect

open access: yes, 2000
A characteristic feature of the Portevin - Le Chatelier effect or the jerky flow is the stick-slip nature of stress-strain curves which is believed to result from the negative strain rate dependence of the flow stress.
A. Arneodo   +35 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Effects of Prestrain and Subsequent Annealing on Tensile Properties of CP-Ti

open access: yesMetals, 2017
The aim of the present work is to investigate the effects of prestrain and subsequent annealing on tensile properties of commercial pure titanium (CP-Ti).
Le Chang, Chang-Yu Zhou, Xiao-Hua He
doaj   +1 more source

Shear response of a smectic film stabilized by an external field

open access: yes, 2000
The response of a field-stabilized two-dimensional smectic to shear stress is discussed. Below a critical temperature the smectic film exhibits elastic response to an infinitesimal shear stress normal to the layering. At finite stresses free dislocations
Franosch, T., Nelson, D. R.
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Study on Hot Open Die Forging Method of Blade Cylinder Root Using AA 5083 Cast Alloy [PDF]

open access: yes한국정밀공학회지, 2019
The blade cylinder root is a key component connecting the blade and pitch bearing of a wind turbine and is 20% of the blade’s manufacturing cost. Blade cylinder roots are manufactured using the open die forging method with steel alloy.
Yong Chul Kwon   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Constitutive Modeling for Flow Stress Behavior of Nimonic 80A Superalloy During Hot Deformation Process

open access: yesHigh Temperature Materials and Processes, 2016
The hot deformation characteristics of nickel-based alloy Nimonic 80A were investigated by isothermal compression tests conducted in the temperature range of 1,000–1,200°C and the strain rate range of 0.01—5 s–1 on a Gleeble-1500 thermomechanical ...
Gu Sendong   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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