Results 71 to 80 of about 1,040,830 (316)
Shear Stress Induces the Release of an Endothelial Elastase: Role in Integrin alpha(v)beta(3)-Mediated FGF-2 Release [PDF]
, 2011 Background/Aims: Laminar shear stress is an important stimulus in the endothelium-dependent control of vascular tone and of vascular remodeling processes.
Hennig, Theres +9 more
core +1 more source
A Study on Hot Open Die Forging Method of Blade Cylinder Root Using AA 5083 Cast Alloy [PDF]
한국정밀공학회지, 2019 The blade cylinder root is a key component connecting the blade and pitch bearing of a wind turbine and is 20% of the blade’s manufacturing cost. Blade cylinder roots are manufactured using the open die forging method with steel alloy.
Yong Chul Kwon +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
High Temperature Materials and Processes, 2016 The hot deformation characteristics of nickel-based alloy Nimonic 80A were investigated by isothermal compression tests conducted in the temperature range of 1,000–1,200°C and the strain rate range of 0.01—5 s–1 on a Gleeble-1500 thermomechanical ...
Gu Sendong +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Evaluation of bed shear stress under turbid flows through measures of flow deceleration
, 2006 In previous work it has been observed that the direct application of the law-of-the-wall in flows of high concentrations of cohesive sediments, results in overestimation of the bed shear stress.
Angelaki, M.
core
Anisotropic eddy-viscosity concept for strongly detached unsteady flows [PDF]
, 2007 The accurate prediction of the flow physics around bodies at high Reynolds number is a challenge in aerodynamics nowadays. In the context of turbulent flow modeling, recent advances like large eddy simulation (LES) and hybrid methods [detached eddy ...
Harran, Gilles +3 more
core +1 more source