Results 71 to 80 of about 7,146,269 (348)

Numerical analysis of a penalization method for the three-dimensional motion of a rigid body in an incompressible viscous fluid

, 2009
We present and analyze a penalization method wich extends the the method of [1] to the case of a rigid body moving freely in an incompressible fluid. The fluid-solid system is viewed as a single variable density flow with an interface captured by a level
Bost, Claire, Cottet, Georges-Henri, Maitre, Emmanuel   +2 more
core   +3 more sources

Flow rule, self-channelization and levees in unconfined granular flows [PDF]

, 2006
Unconfined granular flows along an inclined plane are investigated experimentally. During a long transient, the flow gets confined by quasistatic banks but still spreads laterally towards a well-defined asymptotic state following a nontrivial process ...
A. Mangeney-Castelnau, B. Andreotti, E. Lajeunesse, G. D. R. Midi, O. Dauchot, S. Deboeuf   +5 more
core   +3 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Assessment of Chicken Fecal Contamination Using Microbial Source Tracking (MST) and Environmental DNA (eDNA) Profiling in Silway River, Philippines

Journal of Xenobiotics
The Silway River has historically failed to meet safe fecal coliform levels due to improper waste disposal. The river mouth is located in General Santos City, the tuna capital of the Philippines and a leading producer of hogs, cattle, and poultry.
Lonny Mar Opog, Joan Cecilia Casila, Rubenito Lampayan, Marisa Sobremisana, Abriel Bulasag, Katsuhide Yokoyama, Soufiane Haddout   +6 more
doaj   +1 more source

A Laboratory Study on the Design and Performance Evaluation of Pitot-Tube

Journal of Innovative Science and Engineering, 2023
Due to the increasing demand for water resources worldwide, this commodity and its spatial and temporal properties are of the interest for decision makers and scientists. On the other hand, the accuracy in detecting the physical characteristics of the
Yasemin ESKİ, Babak VAHEDDOOST, Damla YILMAZ   +2 more
doaj   +1 more source

Investigation of exit-velocity stratification effects on jets in a crossflow (STRJET) [PDF]

, 1974
Program determines flow field about jets with velocity stratification exhausting into crossflow. Jets with three different types of exit-velocity stratification have been considered: (a) jets with relatively high-velocity core, (b) jets with relatively ...
Ziegler, H.
core   +1 more source

Nonstationary flow for the Navier-Stokes equations in a cylindrical pipe

, 2011
In cylindrical domain, we consider the nonstationary flow with prescribed inflow and outflow, modelled with Navier-Stokes equations under the slip boundary conditions.
Alame, Besov, Borchers, Galdi, Konieczny, Morimoto, Mucha, Mucha, Neustupa, Rencławowicz, Rencławowicz, Rencławowicz, Rencławowicz, Solonnikov, Takeshita, Valli, Zajączkowski, Zajączkowski, Zajączkowski, Zajączkowski   +19 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Optimization of Heat Transfer and Flow Performance of Microchannel Liquid-Cooled Plate Based on Orthogonal Test

Buildings
Microchannel liquid-cooled plates are widely used in high-performance electronic devices, but their heat transfer performance and pressure drop characteristics face complex challenges in the design process.
Zhengchao Yang, Qiufei Yao, Yu Wang, Junlong Gu, Zhichen Yu, Qipeng Li, Xiaoyi Sun, Xuejing Yang   +7 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source