Results 81 to 90 of about 7,146,269 (348)

Laser Doppler Velocimetry for Joint Measurements of Acoustic and Mean Flow Velocities : LMS-based Algorithm and CRB Calculation

open access: yes, 2009
This paper presents a least mean square (LMS) algorithm for the joint estimation of acoustic and mean flow velocities from laser doppler velocimetry (LDV) measurements.
Degroot, Anne   +3 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Lagrangian velocity and acceleration correlations of large inertial particles in a closed turbulent flow [PDF]

open access: yes, 2015
We investigate the response of large inertial particle to turbulent fluctuations in a inhomogeneous and anisotropic flow. We conduct a Lagrangian study using particles both heavier and lighter than the surrounding fluid, and whose diameters are ...
Machicoane, Nathanaël, Volk, Romain
core   +3 more sources

Prediction of aerodynamic flow fields using convolutional neural networks [PDF]

open access: yesComputational Mechanics, 2019
An approximation model based on convolutional neural networks (CNNs) is proposed for flow field predictions. The CNN is used to predict the velocity and pressure field in unseen flow conditions and geometries given the pixelated shape of the object.
Yaser Afshar   +4 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Vertical Distribution of Nearshore Flow Velocity

open access: yesPolish Maritime Research, 2016
In this paper, a new exponential formed vertical distribution of nearshore flow velocity is constructed, which is simpler in form and more suitable for engineering application. The physical meaning of the new formula is more specific than that of Soulsby.
Chunhui Li   +4 more
doaj   +1 more source

Entrainment, motion and deposition of coarse particles transported by water over a sloping mobile bed

open access: yes, 2016
In gravel-bed rivers, bedload transport exhibits considerable variability in time and space. Recently, stochastic bedload transport theories have been developed to address the mechanisms and effects of bedload transport fluctuations.
Ancey, C., Bohorquez, P., Heyman, J.
core   +3 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Surface oscillations in channeled snow flows

open access: yes, 2007
An experimental device has been built to measure velocity profiles and friction laws in channeled snow flows. The measurements show that the velocity depends linearly on the vertical position in the flow and that the friction coefficient is a first-order
A. Bouchet   +17 more
core   +3 more sources

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