Results 1 to 10 of about 42,420 (122)

Analysis of the risk factors associated with bloodstream infections caused by Candida parapsilosis in pediatric patients and the determinants of fluconazole non-susceptibility: a retrospective 15-year cohort study [PDF]

BMC Infectious Diseases
Background In recent decades, infections caused by C.parapsilosis have been increasingly reported, particularly strains of C.parapsilosis that are non-susceptible to fluconazole. Aims We aimed to evaluate candidemia episodes caused by C. parapsilosis (CP)
Zumrut Sahbudak Bal, Sema Yildirim Arslan, Gizem Guner Ozenen, Gülizar Turan, Kübra Cebeci, Ulgen Celtik, Gulhadiye Avcu, Nihal Karadas, Gulcihan Ozek, Miray Karakoyun, Dilek Yesim Metin, Suleyha Hilmioglu Polat   +11 more
doaj   +2 more sources

Fluconazole-Induced Fixed Drug Eruption With Cross-Reactivity to Clotrimazole—Confirmation With Patch Testing [PDF]

Case Reports in Dermatological Medicine
First described in 1994, fixed drug eruption (FDE) to fluconazole is uncommon but possibly underdiagnosed. Of these, women with vaginal candidiasis remain the most affected, with on average more than four occurrences prior to diagnosis. We present a case
D. S. Sron, P. Martinez, J. Iacobelli, P. Singh, B. M. Ricciardo   +4 more
doaj   +2 more sources

Mutations in TAC1B: a Novel Genetic Determinant of Clinical Fluconazole Resistance in Candida auris

mBio, 2020
Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern. Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most commonly prescribed antifungal agent, and yet it remains unknown what mechanisms
Jeffrey M. Rybak, José F. Muñoz, Katherine S. Barker, Josie E. Parker, Brooke D. Esquivel, Elizabeth L. Berkow, Shawn R. Lockhart, Lalitha Gade, Glen E. Palmer, Theodore C. White, Steve L. Kelly, Christina A. Cuomo, P. David Rogers   +12 more
doaj   +1 more source

In-Vitro Activity of Nano Fluconazole and Conventional Flucon-azole against Clinically Important Dermatophytes

Iranian Journal of Public Health, 2020
Background: Dermatophytosis is one of the most common fungal infections in humans. Antifungals such as fluconazole are effectively used for treating dermatophytosis; however, drug resistance was observed in many cases.
Najmossadat MUSAVI BAFRUI, Seyed Jamal HASHEMI HAZAVEH, Mansour BAYAT   +2 more
doaj   +1 more source

Fluconazole prophylaxis against invasive candidiasis in very low and extremely low birth weight preterm neonates: a systematic review and meta-analysis [PDF]

Clinical and Experimental Pediatrics, 2021
Background Evidence shows that fluconazole prophylaxis is an effective treatment against invasive fungal infections in preterm neonates, however, the most efficient schedule of fluconazole prophylaxis for the colonization and mortality of invasive ...
Mahmoud Robati Anaraki, Masoud Nouri-Vaskeh, Shahram Abdoli Oskoei   +2 more
doaj   +1 more source

Fixed drug eruption caused by fluconazole

Медицинский вестник Юга России, 2023
Objective: to characterize a group of patients with fixed drug erythema (FDE) caused by fluconazole to determine the sensitivity and specificity of the local provocative application test (LPAT) and to evaluate cross-allergenic reactivity with other ...
T. N. Myasnikova, T. V. Latysheva, T. S. Romanova, V. V. Smirnov   +3 more
doaj   +1 more source

Indifferent effect of nonsteroidal anti-inflammatory drugs (NSAIDs) combined with fluconazole against multidrug-resistant Candida auris [PDF]

Current Medical Mycology, 2019
Background and Purpose: Emergence and development of antifungal drug resistance in Candida species constitute a serious concern. Candida auris as an emerging multidrug-resistant fungus is the most important public health threat with high levels of ...
Fatemeh Ahangarkani, Sadegh Khodavaisy, Shahram Mahmoudi, Tahereh Shokohi, Mohammad Sadegh Rezai, Hamed Fakhim, Eric Dannaoui, Saharnaz Faraji, Anuradha Chowdhary, Jacques F. Meis, Hamid Badali   +10 more
doaj   +1 more source

Fluconazole Failure in the Treatment of Coccidioidal Meningitis

Journal of Fungi, 2022
Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis. Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal ...
Simran Gupta, Neil M. Ampel, Molly Klanderman, Marie F. Grill, Janis E. Blair   +4 more
doaj   +1 more source

Copper Acts Synergistically With Fluconazole in Candida glabrata by Compromising Drug Efflux, Sterol Metabolism, and Zinc Homeostasis

Frontiers in Microbiology, 2022
The synergistic combinations of drugs are promising strategies to boost the effectiveness of current antifungals and thus prevent the emergence of resistance.
Ana Gaspar-Cordeiro, Catarina Amaral, Vânia Pobre, Wilson Antunes, Wilson Antunes, Ana Petronilho, Paulo Paixão, Paulo Paixão, António P. Matos, Catarina Pimentel   +9 more
doaj   +1 more source

Overexpression of efflux pump transporter genes and mutations in ERG11 pave the way to fluconazole resistance in Candida tropicalis: A study from a North India region

Journal of Global Antimicrobial Resistance, 2020
Introduction: Fluconazole resistance in Candida tropicalis health care–associated infections is increasing. We investigated the role of efflux pump and mutations in ERG11p conferring fluconazole resistance in C. tropicalis. Materials and methods: A total
Nidhi Pandey, Muktanand Tripathi, Munesh K. Gupta, Ragini Tilak   +3 more
doaj   +1 more source