Results 11 to 20 of about 106,245 (320)

Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2018
Abstract Objectives Extremely premature infants are at high risk of developing invasive candidiasis; fluconazole prophylaxis is safe and effective for reducing invasive candidiasis in this population but further study is needed.
Julie Autmizguine   +44 more
openaire   +4 more sources

A Controlled Trial of Fluconazole to Prevent Fungal Infections in Patients Undergoing Bone Marrow Transplantation [PDF]

open access: bronzeNew England Journal of Medicine, 1992
BACKGROUND AND METHODS Superficial and systemic fungal infections are a major problem among severely immunocompromised patients who undergo bone marrow transplantation.
Jesse L. Goodman   +20 more
openalex   +2 more sources

Fluconazole Resistance and Virulence in In Vitro Induced-Fluconazole Resistant Strains and in Clinical Fluconazole Resistant Strain of Cryptococcus deuterogattii

open access: yesPathogens, 2023
Neuromeningeal cryptococcosis is a life-threatening infection of the central nervous system, caused by encapsulated yeast belonging to the Cryptococcus neoformans and Cryptococcus gattii species complexes. Recent data showed that virulence and antifungal
Sébastien Bertout   +5 more
doaj   +4 more sources

Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans

open access: yesCurrent Medical Mycology, 2017
Background and Purpose: The frequency of opportunistic fungal infections in immunocompromised patients, especially by Candida species, has sharply increased in the last few decades.
Fahimeh Alizadeh   +2 more
doaj   +2 more sources

Epidemiology of Candidemia and Fluconazole Resistance in an ICU before and during the COVID-19 Pandemic Era

open access: yesAntibiotics, 2022
The objectives of this study were to investigate the incidence of candidemia, as well as the factors associated with Candida species distribution and fluconazole resistance, among patients admitted to the intensive care unit (ICU) during the COVID-19 ...
C. Routsi   +13 more
semanticscholar   +1 more source

Indifferent effect of nonsteroidal anti-inflammatory drugs (NSAIDs) combined with fluconazole against multidrug-resistant Candida auris [PDF]

open access: yesCurrent Medical Mycology, 2019
Background and Purpose: Emergence and development of antifungal drug resistance in Candida species constitute a serious concern. Candida auris as an emerging multidrug-resistant fungus is the most important public health threat with high levels of ...
Fatemeh Ahangarkani   +10 more
doaj   +1 more source

Fluconazole prophylaxis against invasive candidiasis in very low and extremely low birth weight preterm neonates: a systematic review and meta-analysis [PDF]

open access: yesClinical and Experimental Pediatrics, 2021
Background Evidence shows that fluconazole prophylaxis is an effective treatment against invasive fungal infections in preterm neonates, however, the most efficient schedule of fluconazole prophylaxis for the colonization and mortality of invasive ...
Mahmoud Robati Anaraki   +2 more
doaj   +1 more source

In-Vitro Activity of Nano Fluconazole and Conventional Flucon-azole against Clinically Important Dermatophytes

open access: yesIranian Journal of Public Health, 2020
Background: Dermatophytosis is one of the most common fungal infections in humans. Antifungals such as fluconazole are effectively used for treating dermatophytosis; however, drug resistance was observed in many cases.
Najmossadat MUSAVI BAFRUI   +2 more
doaj   +1 more source

Fluconazole Failure in the Treatment of Coccidioidal Meningitis

open access: yesJournal of Fungi, 2022
Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis. Current guidelines recommend fluconazole as initial therapy but there has been a paucity of data regarding failure of fluconazole and optimal ...
Simran Gupta   +4 more
doaj   +1 more source

Copper Acts Synergistically With Fluconazole in Candida glabrata by Compromising Drug Efflux, Sterol Metabolism, and Zinc Homeostasis

open access: yesFrontiers in Microbiology, 2022
The synergistic combinations of drugs are promising strategies to boost the effectiveness of current antifungals and thus prevent the emergence of resistance.
Ana Gaspar-Cordeiro   +9 more
doaj   +1 more source

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