Effectiveness of voriconazole therapy for pulmonary cryptococcosis in fluconazole treatment failure: a multicenter real-world study [PDF]
BMC Infectious DiseasesIntroduction Current guidelines recommend fluconazole as first-line therapy for pulmonary cryptococcosis. However, clinical reports indicate that fluconazole treatment fails in some patients.
Dian Yuan +6 more
doaj +2 more sources
Fluconazole-Induced Fixed Drug Eruption With Cross-Reactivity to Clotrimazole—Confirmation With Patch Testing [PDF]
Case Reports in Dermatological MedicineFirst described in 1994, fixed drug eruption (FDE) to fluconazole is uncommon but possibly underdiagnosed. Of these, women with vaginal candidiasis remain the most affected, with on average more than four occurrences prior to diagnosis. We present a case
D. S. Sron +4 more
doaj +2 more sources
Phenotypic and genomic characterization of azole resistance in Portuguese Candida parapsilosis isolates [PDF]
Frontiers in Fungal BiologyIntroductionCandida parapsilosis is a clinically important etiological agent of systemic infections associated with hospital outbreaks, which prevalence has been increasing in the last decade.
Alexandru-Marian Papuc +9 more
doaj +2 more sources
Fluconazole‐Induced Electrolyte Disturbances and Cardiac Toxicity in a CRRT‐Dependent Patient With Acute Renal Failure [PDF]
Clinical Case ReportsFluconazole is a commonly used antifungal drug in clinical practice. Both hyperkalemia and QT interval prolongation are life‐threatening complications of fluconazole.
Fuxia Jian +4 more
doaj +2 more sources
Synergistic Antifungal Effects of Honokiol and Fluconazole Against Oral Candida: Implications for Managing Drug-Resistant Infections. [PDF]
Clin Exp Dent ResABSTRACT Objectives Antifungal drug resistance poses a major challenge in treating oral Candida infections. This study aimed to evaluate the antifungal activity of Honokiol, alone and combined with Fluconazole, against oral Candida isolates, and to investigate its mechanism of action via ergosterol biosynthesis inhibition and cell wall disruption ...
Karched M, Irshad M, Behbehani JM.
europepmc +2 more sources
Mutations in
mBio, 2020 Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern. Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most commonly prescribed antifungal agent, and yet it remains unknown what mechanisms
Jeffrey M. Rybak +12 more
doaj +1 more source
Iranian Journal of Public Health, 2020 Background: Dermatophytosis is one of the most common fungal infections in humans. Antifungals such as fluconazole are effectively used for treating dermatophytosis; however, drug resistance was observed in many cases.
Najmossadat MUSAVI BAFRUI +2 more
doaj +1 more source
Fluconazole prophylaxis against invasive candidiasis in very low and extremely low birth weight preterm neonates: a systematic review and meta-analysis [PDF]
Clinical and Experimental Pediatrics, 2021 Background Evidence shows that fluconazole prophylaxis is an effective treatment against invasive fungal infections in preterm neonates, however, the most efficient schedule of fluconazole prophylaxis for the colonization and mortality of invasive ...
Mahmoud Robati Anaraki +2 more
doaj +1 more source
A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi. [PDF]
, 2014 OBJECTIVE: We have previously reported high ten-week mortality from cryptococcal meningitis in Malawian adults following treatment-induction with 800 mg oral fluconazole (57% [33/58]).
Allain, TJ +10 more
core +12 more sources
Fixed drug eruption caused by fluconazole
Медицинский вестник Юга России, 2023 Objective: to characterize a group of patients with fixed drug erythema (FDE) caused by fluconazole to determine the sensitivity and specificity of the local provocative application test (LPAT) and to evaluate cross-allergenic reactivity with other ...
T. N. Myasnikova +3 more
doaj +1 more source