Results 31 to 40 of about 42,420 (122)

Frequent premature ventricular contractions induced by fluconazole: A case report

open access: yesIDCases
Introduction: Fluconazole is commonly used to treat and prevent fungal infections caused by Candida and Cryptococcus species. Although there have been reports of fatal arrhythmias induced by fluconazole, such as torsades de pointes, there have been ...
Kumi Tamura   +2 more
doaj   +1 more source

Emerging fluconazole resistance: Implications for the management of cryptococcal meningitis

open access: yesMedical Mycology Case Reports, 2018
We present the case of an HIV-seropositive individual with cryptococcal meningitis who was found to have a fluconazole resistant strain of Cryptococcus neoformans.
Edward Mpoza, Joshua Rhein, Mahsa Abassi
doaj   +1 more source

SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway

open access: yesFrontiers in Microbiology, 2020
Candida albicans is a ubiquitous clinical fungal pathogen. Prolonged use of the first-line antifungal agent fluconazole (FLC) has intensified fungal resistance and limited its effectiveness for the treatment of fungal infections.
Xiao-Ning Li   +13 more
doaj   +1 more source

Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in Candida glabrata

open access: yesmSphere, 2023
Candida glabrata is a prominent opportunistic fungal pathogen of humans. The increasing incidence of C. glabrata infections is attributed to both innate and acquired resistance to antifungals.
Andrew N. Gale   +5 more
doaj   +1 more source

Sphingolipid Inhibitors as an Alternative to Treat Candidiasis Caused by Fluconazole-Resistant Strains

open access: yesPathogens, 2021
Candida species are fungal pathogens known to cause a wide spectrum of diseases, and Candida albicans and Candida glabrata are the most common associated with invasive infections.
Rodrigo Rollin-Pinheiro   +6 more
doaj   +1 more source

Candida albicans  Genotyping and Relationship of Virulence Factors with Fluconazole Tolerance in Infected Pediatric Patients

open access: yesInfection and Drug Resistance, 2022
Ghada El-Saeed Mashaly,1 Mayada Sabry Zeid2 1Medical Microbiology and Immunology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 2Infectious Diseases and Malnutrition, Pediatrics Department, Faculty of Medicine, Mansoura University,
Mashaly GE, Zeid MS
doaj  

Comparison of antifungal effects of an experimental fluconazole mouthwash and nystatine mouthwash: An in vitro study

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2013
Introduction: Treatment of oral candidiasis with mouthwashes has several advantages. The aim of the present study was to evaluate the clinical efficacy of a new fluconazole suspension on the Candida albicans and compare its effects with those of nystatin.
Nader Navabi   +4 more
doaj  

Fluconazole and Ibuprofen Combination: A Potential Treatment for Mucosal Candidiasis

open access: yesMedical Laboratory Journal, 2020
Background and objectives: The incidence of drug-resistant candidiasis has increased dramatically. This study aimed to evaluate antifungal effects of fluconazole alone and in combination with ibuprofen on isolates from patients with mucosal candidiasis.  
Tahere Shamoushaki, Leila Fozouni
doaj  

High dose fluconazole in salvage therapy for HIV-uninfected cryptococcal meningitis

open access: yesBMC Infectious Diseases, 2018
Background The 2010 Infectious Diseases Society of America (IDSA) guidelines for management of cryptococcal diseases recommend high dose fluconazole (≥ 800 mg/day), either alone or with other antifungal drugs, as alternative anticryptococcal choices. But
Hua-Zhen Zhao   +8 more
doaj   +1 more source

Candida albicans enhances iron uptake to maintain fluconazole resistance

open access: yesInfection and Immunity
Widespread use of fluconazole has led to the emergence of fluconazole-resistant (FR) Candida spp. causing challenges in clinical treatment. Iron, an essential nutrient, affects the levels of ergosterol (a fluconazole target) in fungal membranes.
Rishabh Sharma   +2 more
doaj   +1 more source

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