Results 31 to 40 of about 110,241 (334)

Overexpression of efflux pump transporter genes and mutations in ERG11 pave the way to fluconazole resistance in Candida tropicalis: A study from a North India region

Journal of Global Antimicrobial Resistance, 2020
Introduction: Fluconazole resistance in Candida tropicalis health care–associated infections is increasing. We investigated the role of efflux pump and mutations in ERG11p conferring fluconazole resistance in C. tropicalis. Materials and methods: A total
Nidhi Pandey, Muktanand Tripathi, Munesh K. Gupta, Ragini Tilak   +3 more
doaj   +1 more source

Silver nanoparticles offer a synergistic effect with fluconazole against fluconazole-resistant Candida albicans by abrogating drug efflux bumps and increasing endogenous ROS.

Infection, Genetics and Evolution, 2020
OBJECTIVES A frequent emergence of drug resistance has been observed and posed great threat to global public health recently. This work aimed to investigate the potential synergistic effect and the underlying mechanisms of AgNPs-fluconazole combination ...
Wenping Sun, D. Jia
semanticscholar   +1 more source

Ibuprofen-Mediated Reversal of Fluconazole Resistance in Clinical Isolates of Candida [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: In view of the increasing prevalence of invasive Candidiasis in today’s health-care scenario and the emergence of fluconazole resistance among clinical isolates of Candida, we sought to determine if Ibuprofen could elicit a reversal of ...
Monika Sharma, Debasis Biswas, Aarti Kotwal, Bhaskar Thakuria, Barnali Kakati, Bhupendra Singh Chauhan, Abhishek Patras   +6 more
doaj   +1 more source

Intensive care unit-related fluconazole use in Spain and Germany: patient characteristics and outcomes of a prospective multicenter longitudinal observational study [PDF]

, 2013
Background: Candida spp. are a frequent cause of nosocomial bloodstream infections worldwide. Objective: To evaluate the use patterns and outcomes associated with intravenous (IV) fluconazole therapy in intensive care units in Spain and Germany ...
Ballus, Jose, Bingold, Tobias Michael, Kaskel, Peter, Krobot, Karl J., Kumar, Ritesh N., Mavros, Panagiotis, Nocea, Gonzalo, Wissing, Heimo   +7 more
core   +1 more source

Fluconazole resistance in Candida species: a current perspective

Infection and Drug Resistance, 2017
Candida albicans and the emerging non-albicans Candida spp. have significant clinical relevance among many patient populations. Current treatment guidelines include fluconazole as a primary therapeutic option for the treatment of these infections, but it
E. Berkow, S. Lockhart
semanticscholar   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure. [PDF]

, 2016
BackgroundIntra-amniotic Candida albicans (C. Albicans) infection is associated with preterm birth and high morbidity and mortality rates. Survivors are prone to adverse neurodevelopmental outcomes.
AJ Wolfberg, Allan H. Jobe, AM Alsaad, AW Gavilanes, AW Gavilanes, B Fleiss, BE Deverman, Benno Küsters, BH Yoon, Boris W. Kramer, C Perego, C Perego, Daan R. M. G. Ophelders, DB DiGiulio, DH Navarathna, E Kuypers, E Kuypers, E Rocha, G Maneenil, HJ Bonestroo, IC Hoogland, JJ Collins, JJ Volpe, JM Dean, John P. Newnham, JR Buser, KN Segovia, LC Schmued, LM Bean, Luc J. Zimmermann, M Atzori, M Gantert, Martin Lammens, Matthew S. Payne, Matthew W. Kemp, MJ Keogh, MS Lionakis, MS Payne, MS Payne, MW Kemp, NY Tsai, O Dammann, O Dammann, R Filipovic, R Galinsky, R Gomez, RL Goldenberg, RL Goldenberg, Ruth Gussenhoven, S Biesmans, S Malaeb, S Rees, S Rivest, SA Back, SA Back, SS Billiards, Suhas G. Kallapur, T Meizoso, TG Wolfs, Tim G. A. M. Wolfs, V Agrawal, V Chau, VV Moudgal, YW Wu   +63 more
core   +4 more sources

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Reduced susceptibility to fluconazole in a cat with histoplasmosis

Journal of Feline Medicine and Surgery Open Reports, 2017
Case summary An 11-year-old neutered male domestic longhair cat was diagnosed with histoplasmosis from fine-needle aspirates of an abdominal lymph node. Lymph node size initially decreased with fluconazole therapy (11.8 mg/kg PO q12h); however, after 13 ...
Janelle S Renschler, Gary D Norsworthy, Rubie A Rakian, Audrey I Rakian, Lawrence J Wheat, Andrew S Hanzlicek   +5 more
doaj   +1 more source

Fluconazole levels in serum and cerebrospinal fluid according to daily dosage in patients with cryptococcosis and other fungal infections

Brazilian Journal of Infectious Diseases, 2018
Fluconazole is extensively used for the treatment of candidiasis and cryptococcosis. Among other factors, successful treatment is related to appropriate fluconazole levels in blood and cerebrospinal fluid.
Letícia Aparecida Schiave, Erika Nascimento, Fernando Crivelenti Vilar, Tissiana Marques de Haes, Osvaldo Massaiti Takayanagui, Cristiane Masetto de Gaitani, Roberto Martinez   +6 more
doaj   +1 more source