Results 51 to 60 of about 110,241 (334)
Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]
, 2019 Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad +4 more
core +1 more source
Anti-Candida targets and cytotoxicity of casuarinin isolated from Plinia cauliflora leaves in a bioactivity-guided study [PDF]
, 2013 Peer reviewedPublisher ...
Gow, Neil A R +8 more
core +4 more sources
Fluconazole Resistance in Isolates of Uncommon Pathogenic Yeast Species from the United Kingdom
Antimicrobial Agents and Chemotherapy, 2019 The triazole drug fluconazole remains one of the most commonly prescribed antifungal drugs, both for prophylaxis in high-risk patients and also as a second-line treatment option for invasive Candida infections.
A. Borman +7 more
semanticscholar +1 more source
Cell wall composition and biofilm formation of azoles-susceptible and -resistant Candida glabrata strains [PDF]
, 2011 In the present study, three strains of Candida glabrata have been investigated to shed light on the mechanisms involved in azole resistance during adherence and biofilm formation.
Vitali, Alberto +6 more
core +5 more sources
Vaginal yeasts in the era of "over the counter" antifungals [PDF]
, 2000 OBJECTIVE: To establish whether there has been any rise in the prevalence of non-albicans Candida species isolated from vaginal swabs since the introduction of “over the counter” antifungal treatments.
Ashbee, H.R. +4 more
core +2 more sources
Emerging Infectious Diseases, 2018 We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea.
Y. Choi +11 more
semanticscholar +1 more source
Microbiology Spectrum, 2021 Resistance to fluconazole is one of clinical characteristics most frequently challenging the treatment of invasive Candida auris infections, and is observed among >90% of all characterized clinical isolates. In this work, the native C. auris ERG11 allele
Jeffrey M. Rybak +5 more
doaj +1 more source
Use of Estimating Equations for Dosing Antimicrobials in Patients with Acute Kidney Injury Not Receiving Renal Replacement Therapy. [PDF]
, 2018 Acute kidney injury (AKI) can potentially lead to the accumulation of antimicrobial drugs with significant renal clearance. Drug dosing adjustments are commonly made using the Cockcroft-Gault estimate of creatinine clearance (CLcr). The Modified Jelliffe
Awdishu, Linda +5 more
core +2 more sources
Synergistic Effects of Amiodarone and Fluconazole on Candida tropicalis Resistant to Fluconazole [PDF]
Antimicrobial Agents and Chemotherapy, 2013 ABSTRACT There have recently been significant increases in the prevalence of systemic invasive fungal infections. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs. This fact, coupled with the increased frequency of cross-resistance, makes it necessary to
Thalles B. Grangeiro +11 more
openaire +3 more sources
Journal of Global Antimicrobial Resistance, 2022 : Objectives: The study aimed to evaluate four selective serotonin reuptake inhibitors (SSRIs) as modifiers of fluconazole activity against resistant strains of Candida glabrata. Methods: The effect of SSRIs on fluconazole activity was studied using the
Bashar A. Alkhalifa +3 more
doaj +1 more source