Results 51 to 60 of about 106,245 (320)

Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea

Emerging Infectious Diseases, 2018
We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea.
Y. Choi, Yae‐Jean Kim, D. Yong, Jung-Hyun Byun, Taek Soo Kim, Y. Chang, Min Ji Choi, Seung Ah Byeon, E. Won, S. Kim, M. Shin, Jong‐Hee Shin   +11 more
semanticscholar   +1 more source

Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease.

New England Journal of Medicine, 2007
BACKGROUND Invasive fungal infections are an important cause of morbidity and mortality after allogeneic hematopoietic stem-cell transplantation. METHODS In an international, randomized, double-blind trial, we compared oral posaconazole with oral ...
A. Ullmann, J. Lipton, D. Vesole, P. Chandrasekar, A. Langston, S. Tarantolo, H. Greinix, Wellington Morais de Azevedo, V. Reddy, N. Boparai, L. Pedicone, H. Patiño, S. Durrant   +12 more
semanticscholar   +1 more source

First Report of Ventriculoperitoneal Shunt Infection due to Cyberlindnera fabianii. [PDF]

, 2015
Fungal infections in the central nervous system (CNS) are associated with significant morbidity and death. Transient fungemia in immunocompetent patients without any other risk factors for fungemia has been suggested as a possible mechanism that may lead
Baghdadi, Jonathan, Hemarajata, Peera, Humphries, Romney, Kelesidis, Theodoros   +3 more
core   +3 more sources

A randomized, double-blind study of amorolfine 5% nail lacquer with oral fluconazole compared with oral fluconazole alone in the treatment of fingernail onychomycosis

Indian Journal of Dermatology, 2019
Background: It is a challenge to treat onychomycosis due to frequent treatment failures and relapses. Systemic and topical therapies need to be combined to improve cure rates.
Somodyuti Chandra, Karan Sancheti, Indrashis Podder, Anupam Das, Tushar Kanti Sarkar, Moitreyee Chowdhury, Amrita Sil, Susmita Bhattacharya, Nilay Kanti Das   +8 more
doaj   +1 more source

Fluconazole Assists Berberine To Kill Fluconazole-Resistant Candida albicans [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT It was found in our previous study that berberine (BBR) and fluconazole (FLC) used concomitantly exhibited a synergism against FLC-resistant Candida albicans in vitro . The aim of the present study was to clarify how BBR and FLC worked synergistically and the underlying mechanism ...
De-Dong Li, Eleftherios Mylonakis, Yi Xu, Ming-Bang Li, Lan-Xue Zhao, Dan-Dan Hu, Yuanying Jiang, Da-Zhi Zhang, Liang-hua Zhu, Hua Quan, Yan Wang   +10 more
openaire   +3 more sources

Tolerability of long-term fluconazole therapy

Journal of Antimicrobial Chemotherapy, 2018
BACKGROUND Fluconazole is a commonly prescribed first-generation triazole antifungal. Although the toxicity profile of fluconazole has been evaluated in clinical trials, there are scant data regarding its tolerability with long-term therapy.
M. Davis, M. Nguyen, M. Donnelley, G. Thompson   +3 more
semanticscholar   +1 more source

Molecular Evaluation of the mRNA Expression of the ERG11, ERG3, CgCDR1, and CgSNQ2 Genes Linked to Fluconazole Resistance in Candida glabrata in a Colombian Population

Journal of Fungi
Introduction: The study of Candida glabrata genes associated with fluconazole resistance, from a molecular perspective, increases the understanding of the phenomenon with a view to its clinical applicability.
Leidy Yurany Cárdenas Parra, Ana Elisa Rojas Rodríguez, Jorge Enrique Pérez Cárdenas, Juan Manuel Pérez-Agudelo   +3 more
doaj   +1 more source

Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance

Microbiology Spectrum, 2021
Resistance to fluconazole is one of clinical characteristics most frequently challenging the treatment of invasive Candida auris infections, and is observed among >90% of all characterized clinical isolates. In this work, the native C. auris ERG11 allele
Jeffrey M. Rybak, Cheshta Sharma, Laura A. Doorley, Katherine S. Barker, Glen E. Palmer, P. David Rogers   +5 more
doaj   +1 more source

Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis. [PDF]

, 2018
BACKGROUND: Cryptococcal meningitis (CM) causes an estimated 180,000 deaths annually, predominantly in sub-Saharan Africa, where most patients receive fluconazole (FLC) monotherapy. While relapse after FLC monotherapy with resistant strains is frequently
Berman, J, Bicanic, T, Fisher, MC, Harrison, TS, Hope, W, Kivuyo, S, Kwon-Chung, J, Mfinanga, S, Molloy, SF, Needleman, L, Rhodes, J, Rugemalila, J, Segal, ES, Stone, NR   +13 more
core   +4 more sources

Bioinspirierte Kationische Antimikrobielle Polymere

Angewandte Chemie, EarlyView.
Dieser Übersichtsartikel behandelt Membran‐aktive kationische Polymere mit antimikrobiellen Eigenschaften. Im Fokus stehen Aspekte wie die Polymerarchitektur, Stimuli‐responsive antimikrobielle Polymere sowie Synergien von Polymeren und anderen Verbindungen.
Heliya Javadi, Anne‐Catherine Lehnen, Matthias Hartlieb   +2 more
wiley   +1 more source