Bridging the "Valley of Death" in Antifungal Therapy: Next-Generation Biomimetic and Exosome-Inspired Nanocarriers for Invasive Candidiasis. [PDF]
Yoğurtçu BM, Yilmaz I.
europepmc +1 more source
Dual-Targeting, Hybrid Antifungal Agents Targeting Candida albicans-An Overview. [PDF]
Pal S +5 more
europepmc +1 more source
An open multicentre comparative study of the efficacy, safety and tolerance of fluconazole and itraconazole in the treatment of cancer patients with oropharyngeal candidiasis [PDF]
Oropharyngeal candidiasis is a frequent infection in cancer patients who receive cytotoxic drugs. In this study, the efficacy, safety and tolerance of fluconazole and itraconazole were compared in non-neutropenic cancer patients with oropharyngeal candidiasis.
Bart Jan Kullberg +2 more
exaly +7 more sources
Related searches:
Safety and Tolerability of Fluconazole in Children
Antimicrobial Agents and Chemotherapy, 1999ABSTRACT The safety profile of fluconazole was assessed for 562 children (ages, 0 to 17 years) comprising 323 males and 239 females. The data are derived from 12 clinical studies of fluconazole as prophylaxis or treatment for a variety of fungal infections in predominantly immunocompromised patients.
V, Novelli, H, Holzel
openaire +2 more sources
Isolation of fluconazole-tolerant micromycetes onto different cultivation media
Folia Microbiologica, 2002On studying the dependence of quality and/or quantity of environmental fluconazole-tolerant micromycetes on culture medium in vitro, the highest number of isolates was obtained in Sabouraud agar (SA) without fluconazole (59 CFU/mg of soil sample at 25 degrees C and 31 CFU/mg at 37 degrees C).
Z, Kunová, E, Piecková
openaire +2 more sources
Efficacy, safety and toleration of fluconazole suppositories in the treatment of oral candidosis
Mycoses, 1999An open multicentre, non‐comparative study was conducted in three countries to investigate the efficacy, safety and tolerance of fluconazole suppositories in the treatment of oropharyngeal candidosis. Patients received fluconazole 100 mg day−1 in the form of suppositories or capsules.
A, Plettenberg +5 more
openaire +2 more sources
Impact of tolerance to fluconazole on treatment response in Candida albicans bloodstream infection
Mycoses, 2020AbstractBackgroundTreatment of Candida albicans bloodstream infection with fluconazole is associated with significant mortality despite in vitro susceptibility to the drug.ObjectivesWe sought to determine whether tolerance to fluconazole is predictive of treatment failure.MethodsWe reviewed patients with monomicrobial C albicans bloodstream infection ...
Tal Levinson +5 more
openaire +2 more sources
Emerging Evidence of Selection of Fluconazole-Tolerant Fungi in Surgical Intensive Care Units
Archives of Surgery, 1997To determine whether increased use of fluconazole has coincided with a shift in the relative proportion of fluconazole-tolerant species isolated from critically ill surgical patients in 2 university hospitals.Microbiological data and fluconazole administration frequencies were reviewed among patients treated in the surgical intensive care units (SICUs)
T G, Gleason +4 more
openaire +2 more sources
Candida albicans Msi3p, a homolog of the Saccharomyces cerevisiae Sse1p of the Hsp70 family, is involved in cell growth and fluconazole tolerance. [PDF]
We investigated the cellular function of Msi3p, belonging to the heat shock protein 70 family, in Candida albicans. The mutant strain tetMSI3 was generated, in which MSI3 was controlled by a tetracycline-repressive promoter, because there is evidence to suggest that MSI3 is an essential gene. We controlled the MSI3 expression level by doxycycline (DOX)
Keigo Ueno, Jun-ichi Nagao, Tamaki Cho
exaly +3 more sources
There are limited studies about the presence of Candida species (Candida spp.) and ABC genotypes in hospital acquired urinary tract infection (UTI) in children.the study aimed at identification of Candida spp. associated with candiduria in children, detection of fluconazole tolerance and biofilm formation and genotyping of C.
Maysaa El Sayed Zaki
exaly +3 more sources

