Results 151 to 160 of about 5,860 (175)

Efficacy, safety and toleration of fluconazole suppositories in the treatment of oral candidosis

Mycoses, 1999
An open multicentre, non‐comparative study was conducted in three countries to investigate the efficacy, safety and tolerance of fluconazole suppositories in the treatment of oropharyngeal candidosis. Patients received fluconazole 100 mg day−1 in the form of suppositories or capsules.
A, Plettenberg, A, Stoehr, W, Heise, F, Schlote, E, Sarnow, M, Migdal   +5 more
openaire   +2 more sources

Isolation of fluconazole-tolerant micromycetes onto different cultivation media

Folia Microbiologica, 2002
On studying the dependence of quality and/or quantity of environmental fluconazole-tolerant micromycetes on culture medium in vitro, the highest number of isolates was obtained in Sabouraud agar (SA) without fluconazole (59 CFU/mg of soil sample at 25 degrees C and 31 CFU/mg at 37 degrees C).
Z, Kunová, E, Piecková
openaire   +2 more sources

Impact of tolerance to fluconazole on treatment response in Candida albicans bloodstream infection

Mycoses, 2020
AbstractBackgroundTreatment of Candida albicans bloodstream infection with fluconazole is associated with significant mortality despite in vitro susceptibility to the drug.ObjectivesWe sought to determine whether tolerance to fluconazole is predictive of treatment failure.MethodsWe reviewed patients with monomicrobial C albicans bloodstream infection ...
Tal Levinson, Alon Dahan, Anna Novikov, Yael Paran, Judith Berman, Ronen Ben‐Ami   +5 more
openaire   +2 more sources

Candida albicans Msi3p, a homolog of the Saccharomyces cerevisiae Sse1p of the Hsp70 family, is involved in cell growth and fluconazole tolerance [PDF]

FEMS Yeast Research, 2012
We investigated the cellular function of Msi3p, belonging to the heat shock protein 70 family, in Candida albicans. The mutant strain tetMSI3 was generated, in which MSI3 was controlled by a tetracycline-repressive promoter, because there is evidence to suggest that MSI3 is an essential gene. We controlled the MSI3 expression level by doxycycline (DOX)
Jun-Ichi Nagao, Tamaki Cho, Jun Uno
exaly   +3 more sources

Molecular study of candiduria in pediatric patients in in relation to biofilm formation and fluconazole tolerance

Diagnostic Microbiology and Infectious Disease
There are limited studies about the presence of Candida species (Candida spp.) and ABC genotypes in hospital acquired urinary tract infection (UTI) in children.the study aimed at identification of Candida spp. associated with candiduria in children, detection of fluconazole tolerance and biofilm formation and genotyping of C.
Maysaa El Sayed Zaki, Noha Mostafa Mahmoud, Mayada Sabry Zeid   +2 more
exaly   +3 more sources

Emerging Evidence of Selection of Fluconazole-Tolerant Fungi in Surgical Intensive Care Units

Archives of Surgery, 1997
To determine whether increased use of fluconazole has coincided with a shift in the relative proportion of fluconazole-tolerant species isolated from critically ill surgical patients in 2 university hospitals.Microbiological data and fluconazole administration frequencies were reviewed among patients treated in the surgical intensive care units (SICUs)
T G, Gleason, A K, May, D, Caparelli, B M, Farr, R G, Sawyer   +4 more
openaire   +2 more sources

Electrochemical Strategy for Eradicating Fluconazole-Tolerant Candida albicans Using Implantable Titanium

ACS Applied Materials & Interfaces, 2019
A persistent problem in modern health care derives from the overwhelming presence of antibiotic-resistant microbes on biomaterials, more specifically, fungal growth on metal-based implants. This study seeks to investigate the antifungal properties of low-level electrochemical treatments delivered using titanium electrodes against Candida albicans.
Eloise Parry-Nweye, Nna-Emeka Onukwugha, Sricharani Rao Balmuri, Jackie L. Shane, Dongyeop Kim, Hyun Koo, Tagbo H. R. Niepa   +6 more
openaire   +2 more sources

Pharmacokinetics and tolerance of fluconazole suppositories in healthy volunteers.

Arzneimittel-Forschung, 1993
Fluconazole (Diflucan, CAS 86386-73-4) suppositories offer a novel way to administer this systemically active antimycotic. The pharmacokinetics and toleration of this new formulation have now been examined in healthy adult volunteers. In crossover experiments the bioequivalence was demonstrated for 200 mg suppositories and 200 mg capsules, and for 25 ...
G, Pfaff, T, Zimmermann, P, Lach, R, Yeates, G, Simon, A, Wildfeuer   +5 more
openaire   +1 more source

The impact of growth conditions on biofilm formation and the cell surface hydrophobicity in fluconazole susceptible and tolerant Candida albicans

Folia Microbiologica, 2014
The influence of acidic (5.6) and neutral (7.0) pH and glucose concentrations (0.9 and 2 %) was determined in in vitro biofilm formation and the cell surface hydrophobicity (CSH) in fluconazole (FLC) susceptible and tolerant yeasts of Candida albicans.
Anna, Kolecka, Dušan, Chorvát, Helena, Bujdáková   +2 more
openaire   +2 more sources

[Fluconazole in therapy of candidiasis of the oropharyngeal space in patients with HIV infection. Results of an open multicenter study of assessing the effectiveness and tolerance of fluconazole].

Medizinische Klinik (Munich, Germany : 1983), 1992
50 HIV-positive patients (CDC stage III to VI) with oral candidiasis proven by culture and typical clinical findings were treated with fluconazole (50 to 100 mg/day) over a period of eight to 22 days. After completion of treatment, clinical signs of oral candidiasis had disappeared in 45/50 patients. In 10/50 patients, however, increased concentrations
B, Tschechne, U, Brunkhorst, M, Ruhnke, M, Trautmann, S, Dempe, H, Deicher   +5 more
openaire   +1 more source