Results 101 to 110 of about 9,329 (213)

Liposomal Amphotericin B and Flucytosine Versus Micafungin in Treatment of Candida Endocarditis

, 2020
Candida endocarditis is a life-threatening, opportunistic fungal infection of the endocardium. The mortality rate of Candida endocarditis is approximately 50% and has been increasing in incidence over recent years.
Yanker, Anton Matthew
core  

Clinical aPDT's effect on Candida albicans: Antifungal susceptibility, virulence gene expression, and correlation with leukocyte and neutrophil counts

Photodiagnosis and Photodynamic Therapy
Background: Our previous clinical trial demonstrated that antimicrobial photodynamic therapy (aPDT) with methylene blue (MB) and potassium iodide (KI) effectively killed Candida albicans (C.
Meixia Du, Weijun Xuan, Michael R Hamblin, Liyi Huang   +3 more
doaj   +1 more source

In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp

, 2002
We investigated the in vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine, against Aspergillus spp.
Warn, P. A., Sharp, A., Mosquera, J., Denning, D. W.; id_orcid, Moore, C. B.   +4 more
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Model‐Informed Drug Development of a Sustained Release Formulation of Flucytosine in the Treatment of Cryptococcal Meningitis: A Case Study Using Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics & Systems Pharmacology
This paper presents a case study demonstrating the application of model‐informed drug development (MIDD) and early modeling integration in the development of a sustained release (SR) formulation of flucytosine for cryptococcal meningoencephalitis (CM) in
Johanna Eriksson, Erik Sjögren, Jean‐Yves Gillon, Henri Caplain, Vishal Goyal, Vijay Satam, Stephen Robinson, Isabela Ribeiro, Marylore Chenel   +8 more
doaj   +1 more source

High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial.

, 2008
BACKGROUND: The standard therapy for human immunodeficiency virus (HIV)-associated cryptococcal meningitis of amphotericin B (AmB; 0.7 mg/kg per day) plus flucytosine frequently takes >2 weeks to sterilize the cerebral spinal fluid, and acute mortality ...
Harrison, Thomas, Tihana Bicanic, Annemarie Brouwer, Meintjes, Graeme, Linda-gail Bekker, Angela Loyse, Kevin Rebe, Shabbar Jaffar, Thomas Harrison, Bicanic, Tihana, Brouwer, Annemarie, Rebe, Kevin, Robin Wood, Bekker, Linda-Gail, Jaffar, Shabbar, Graeme Meintjes, Loyse, Angela, Wood, Robin   +17 more
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MIC range (μg/mL) of LIF 12560 and LIF-E10 against amphotericin B, 5-flucytosine, fluconazole, itraconazole and voriconazole.

, 2016
MIC range (μg/mL) of LIF 12560 and LIF-E10 against amphotericin B, 5-flucytosine, fluconazole, itraconazole and voriconazole.
Isabela Haddad Peron (3154302), Franqueline Reichert-Lima (3154314), Maria Luiza Moretti (3154305), Cristiane Kibune Nagasako (3154317), Angelica Zaninelli Schreiber (3154320), Luzia Lyra (3154308), Ariane Fidelis Busso-Lopes (3154311)   +6 more
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Targeting brain cells with glutathione-modulated nanoliposomes: in vitro and in vivo study

Drug Design, Development and Therapy, 2015
Heba F Salem,1 Sayed M Ahmed,2 Ashraf E Hassaballah,3 Mahmoud M Omar1,4 1Department of Pharmaceutics and Industrial Pharmacy, Beni-suef University, 2Department of Industrial Pharmacy, Assiut University, 3Department of Clinical Pathology, Faculty of ...
Salem HF, Ahmed SM, Hassaballah AE, Omar MM   +3 more
doaj  

In-vitro interactions of itraconazole with flucytosine against clinical isolates of Cryptococcus neoformans.

, 1999
Treatment failures can occur in AIDS patients infected with Cryptococcus neoformans, despite aggressive antifungal therapy. Combination regimens with additive or synergic drugs could provide additional options for treating cryptococcosis.
GIACOMETTI, Andrea, Di Francesco LF, BARCHIESI, FRANCESCO, Caselli F, Gallo D, SCALISE, Giorgio, Arzeni D   +6 more
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Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea [PDF]

, 2012
The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.
이경원
core  

A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans

, 2012
Cryptococcosis, caused by the basidiomycetous fungus Cryptococcus neoformans , is responsible for more than 600,000 deaths annually in AIDS patients. Flucytosine is one of the most commonly used antifungal drugs for its treatment,
Joseph Heitman, Nielsen, Kirsten, Bahn, Yong-Sun, Anna Floyd, Song, Min-Hee, Yong-Sun Bahn, Yoon, Ja-Kyung, Theodore C. White, Min Su Kim, Ja-Kyung Yoon, Floyd, Anna, Kim, Min Su, Strain, Anna K., Judith N. Nielsen, Nielsen, Judith N., White, Theodore C., Lee, Jang-Won, Jang-Won Lee, Min-Hee Song, Heitman, Joseph, Kirsten Nielsen, Anna K. Strain   +21 more
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