Results 91 to 100 of about 2,218 (130)

CgFPS1 and CgFPS2 expression decreases the accumulation of 5-flucytosine in C. glabrata cells.

, 2015
Time-course accumulation of [3H]-flucytosine in non-adapted KUE100 (♦), KUE100_Δcgfps1 (■) and KUE100_Δcgfps2 (▲) strains, during cultivation in BM liquid medium in the presence of 3mg/L of unlabelled 5-flucytosine.
Mafalda Cavalheiro (782767), Rui Santos (490726), Catarina Costa (322963), Andreia Ponte (782765), Miguel Cacho Teixeira (782769), Hiroji Chibana (30368), Pedro Pais (782766), Takashi Yaguchi (782768)   +7 more
core   +1 more source

Heightened Efficacy of Anidulafungin When Used in Combination with Manogepix or 5-Flucytosine against Candida auris In Vitro [PDF]

, 2023
Candida auris is an emerging, multidrug-resistant fungal pathogen that causes refractory colonization and life-threatening, invasive nosocomial infections. The high proportion of C.
DD Thomson (21935480), LLH John (21953459), M Hoenigl (21839471), EM Bignell (21953462), TS Harrison (21482639), T Bicanic (18374478), AJP Brown (21862340)   +6 more
core  

Granulocytopenia and Thrombocytopenia Associated with Combination Therapy of Amphotericin B and Low-Dose Flucytosine in a Patient with Cryptococcal Meningitis

, 1989
A patient was admitted complaining of fever and headache. He was suspected of meningitis due to nuchal rigidity, and a lumbar puncture was performed. The patient was diagnosed as having cryptococcal meningitis, as Cryptococcus neoformans was found in an
Kunihiko Shindo, Masanori Matsumura, Tadaoki Mizuno, Yoshimi Hashimoto, Akira Ito, Yutaka Matsumoto, Hiroshi Shionoiri   +6 more
core   +1 more source

Fluconazole plus flucytosine versus fluconazole alone for adults with HIV-associated cryptococcal antigenaemia identified through screening: a multi-centre phase III randomised-controlled trial

Trials
Background Despite the expansion of antiretroviral treatment programmes, the incidence and mortality of HIV-associated cryptococcal meningitis remain high in Africa. Cryptococcal antigen (CrAg) in the blood precedes meningitis.
Kyla Murphy, Jeremy S. Nel, Mahomed-Yunus Moosa, Douglas P. Wilson, Merika Tsitsi, Sayoki Mfinanga, Sokoine Kivuyo, Denise Kyazze, Nowshad Alam, Graeme Meintjes, Michelle Eriksson, Jack Adams, Colin Menezes, Ebrahim Variava, John Black, Marise Bremer, Vu Quoc Dat, Thuy Le, Charlotte Schutz, Angela Loyse, Rachel M. Wake, David S. Lawrence, Duolao Wang, Shabbar Jaffar, Joseph N. Jarvis, Thomas S. Harrison, Síle F. Molloy, Nelesh P. Govender   +27 more
doaj   +1 more source

Induction Treatment for HIV-Associated Cryptococcal Meningitis: Where Have We Been and Where Are We Going?

Microorganisms
Cryptococcal meningitis remains a leading cause of morbidity and mortality among individuals with HIV/AIDS, particularly in resource-limited settings. Treatment begins with induction therapy followed by consolidation and maintenance.
Dominique Milsap, Madison Okuno, Enos Kigozi, Timothy Mugabi, Ssekindi Faizo, Aleksandra Bajer, Jane Gakuru, Nathan C. Bahr   +7 more
doaj   +1 more source

Successful use of isavuconazole as secondary prophylaxis of cryptococcal meningitis in a person living with HIV and AIDS: a case report

Therapeutic Advances in Infectious Disease
Cryptococcal meningitis (CM) is a severe opportunistic infection in people living with HIV (PLWH). We report a 54-year-old man with advanced HIV infection who presented with CM due to Cryptococcus neoformans .
Carmela Pinnetti, Alessandro Giacinta, Federico Cecilia, Francesco Baldini, Annalisa Mondi, Saba Gebremeskel Teklè, Susanna Grisetti, Marta Camici, Donatella Vincenti, Stefania Carrara, Carla Fontana, Andrea Antinori   +11 more
doaj   +1 more source

High-dose amphotericin B with flucytosine for the treatment of cryptococcal meningitis in HIV-infected patients: a randomized trial.

, 2008
BACKGROUND: The standard therapy for human immunodeficiency virus (HIV)-associated cryptococcal meningitis of amphotericin B (AmB; 0.7 mg/kg per day) plus flucytosine frequently takes >2 weeks to sterilize the cerebral spinal fluid, and acute mortality ...
Harrison, Thomas, Tihana Bicanic, Annemarie Brouwer, Meintjes, Graeme, Linda-gail Bekker, Angela Loyse, Kevin Rebe, Shabbar Jaffar, Thomas Harrison, Bicanic, Tihana, Brouwer, Annemarie, Rebe, Kevin, Robin Wood, Bekker, Linda-Gail, Jaffar, Shabbar, Graeme Meintjes, Loyse, Angela, Wood, Robin   +17 more
core   +1 more source

MICs Distribution (μg/mL) of 143 Candida albicans bloodstream isolates against amphotericin B, 5-flucytosine, fluconazole, itraconazole, voriconazole and caspofungin.

, 2016
MICs Distribution (μg/mL) of 143 Candida albicans bloodstream isolates against amphotericin B, 5-flucytosine, fluconazole, itraconazole, voriconazole and caspofungin.
Isabela Haddad Peron (3154302), Franqueline Reichert-Lima (3154314), Maria Luiza Moretti (3154305), Cristiane Kibune Nagasako (3154317), Angelica Zaninelli Schreiber (3154320), Luzia Lyra (3154308), Ariane Fidelis Busso-Lopes (3154311)   +6 more
core   +1 more source

Study on the impact of biofilm formation by Candida albicans in recurrent vulvovaginal candidiasis on drug susceptibility

Frontiers in Cellular and Infection Microbiology
BackgroundVulvovaginal candidiasis (VVC) and recurrent VVC (RVVC) are common fungal infections in women, often complicated by recurrence and treatment resistance.
Sainan Li, Zijia Shen, Suke Wang, Yongmei Peng, Wenjin Qi   +4 more
doaj   +1 more source

Abstracts From AIDS 2026, the 26th International AIDS Conference, 26 – 31 July 2026 Rio de Janeiro, Brazil & virtual

Journal of the International AIDS Society, Volume 29, Issue S4, July 2026.
wiley   +1 more source