Results 91 to 100 of about 9,329 (213)

Antifungal Susceptibilities of Cryptococcus neoformans

Emerging Infectious Diseases, 2004
Susceptibility profiles of medically important fungi in less-developed countries remain uncharacterized. We measured the MICs of amphotericin B, 5-flucytosine, fluconazole, itraconazole, and ketoconazole for Cryptococcus neoformans clinical isolates from
Lennox K. Archibald, Marion J. Tuohy, Deborah A. Wilson, Okey Nwanyanwu, Peter N. Kazembe, Somsit Tansuphasawadikul, Boonchuay Eampokalap, Achara Chaovavanich, L.Barth Reller, William R. Jarvis, Gerri S. Hall, Gary W. Procop   +11 more
doaj   +1 more source

Flucytosine and Amphotericin B Coadministration Induces Dose-Related Renal Injury

Dose-Response, 2017
Invasive fungal infections remain an important clinical problem, and despite recent approaches, they bring high morbidity and mortality. Combination therapies are the most effective; however, adverse effects need to be considered. In this study, we aimed
Alexandra Folk, Cornel Balta, Hildegard Herman, Alexandra Ivan, Oana Maria Boldura, Lucian Paiusan, Aurel Ardelean, Anca Hermenean   +7 more
doaj   +1 more source

Flucytosine resistance in Cryptococcus gattii is indirectly mediated by the FCY2-FCY1-FUR1 pathway [PDF]

, 2018
Cryptococcosis is an opportunistic fungal infection caused by members of the two sibling species complexes: Cryptococcus neoformans and Cryptococcus gattii.
Shawn R Lockhart, Vu, Kiem, Dreibe, Elizabeth M, Lockhart, Shawn R, Elizabeth M Dreibe, Roe, Chandler C, Thompson, George R, Wieland Meyer, Angie Gelli, Jane E Sykes, Chandler C Roe, George R Thompson, David M Engelthaler, Sykes, Jane E, Kiem Vu, Engelthaler, David M, Gelli, Angie, Meyer, Wieland   +17 more
core   +1 more source

One-Step Continuous Flow Synthesis of Antifungal WHO Essential Medicine Flucytosine Using Fluorine

, 2017
In Africa around 625 000 mortalities per annum (20% of HIV/AIDS related deaths) are due to the affects of the Cryptococcal meningitis (CM) fungal infection. Recently, the World Health Organisation (WHO) and the Infectious Disease Society of America (IDSA)
Laurent Pichon (358645), Annelyse Conte (3633895), Graham Sandford (1951078), Rabion, A., Grenier, S., Antal Harsanyi (3633889), Conte, A., Alain Rabion (3633892), Harsanyi, A., Pichon, L., Sandford, G., Sandrine Grenier (3633886)   +11 more
core   +1 more source

Induction Treatment for HIV-Associated Cryptococcal Meningitis: Where Have We Been and Where Are We Going?

Microorganisms
Cryptococcal meningitis remains a leading cause of morbidity and mortality among individuals with HIV/AIDS, particularly in resource-limited settings. Treatment begins with induction therapy followed by consolidation and maintenance.
Dominique Milsap, Madison Okuno, Enos Kigozi, Timothy Mugabi, Ssekindi Faizo, Aleksandra Bajer, Jane Gakuru, Nathan C. Bahr   +7 more
doaj   +1 more source

Cell wall damage followed by remodeling occurs during adaptation to 5-flucytosine stress.

, 2015
A) C. glabrata KUE100 cells exposed to lyticase stress were harvested in the exponential phase of growth in the absence of stress (♦) or upon 30 min of exposure to 0.7 mg/L 5-flucytosine (■), or in the exponential phase of growth reached upon adaptation ...
Mafalda Cavalheiro (782767), Rui Santos (490726), Catarina Costa (322963), Andreia Ponte (782765), Miguel Cacho Teixeira (782769), Hiroji Chibana (30368), Pedro Pais (782766), Takashi Yaguchi (782768)   +7 more
core   +1 more source

Flucytosine [PDF]

Reactions Weekly, 2020
openaire   +2 more sources

Itraconazole compared with amphotericin B plus flucytosine in AIDS patients with cryptococcal meningitis

, 1992
We conducted a comparison of itraconazole versus amphotericin B plus flucytosine in the initial treatment of cryptococcal meningitis in patients with AIDS and established the efficacy of itraconazole as maintenance treatment. The trial was a prospective,
van Boxtel, C. J., Portegies, P., Stam, J., Tiessens, G., de Gans, J., Eeftinck Schattenkerk, J. K., van Ketel, R. J.   +6 more
core   +1 more source

In vitro activity of amphotericin B and itraconazole in combination with flucytosine, sulfadiazine and quinolones against Exophiala spinifera.

, 2003
Item does not contain fulltextThe combined effects of antifungal and antibiotic drugs against Exophiala spinifera were evaluated in vitro by the chequer-board method, calculated as a fractional inhibitory concentration (FIC) index.
Vitale, R.G., Hoog, G.S. de, Afeltra, J., Rijs, A.J.M.M., Verweij, P.E.   +4 more
core   +1 more source

Effect of flucytosine on paramagnetic properties of Cladosporium cladosporioides

, 2009
Zbadano właściwości paramagnetyczne upigmentowanych grzybów glebowych Cladosporium cladosporioides oraz ich kompleksów z flucytozyną z zastosowaniem spektroskopii EPR.
Zdybel, M., Cieśla, H., Pilawa, B., Witoszyńska, T., Buszman, E.   +4 more
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