Results 71 to 80 of about 9,369 (213)

Diagnosis and Treatment of Foot Fusarium Infection Confirmed by Molecular Identification: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Fusarium spp. are opportunistic fungal pathogens, with an increasing incidence of infection observed in immunocompromised populations. Due to the non‐specific clinical manifestations of cutaneous Fusarium infections, they are often misdiagnosed or overlooked.
Yulin Wang, Danyue He, Jie Hu, Qi Zhao, Ruyi Wang, Yiyang Hu, Jia Cai, Xiangning Li, Lili Tang, Xing Fan   +9 more
wiley   +1 more source

Flucytosine for treatment of Candida albicans in H1N1-positive patient [PDF]

, 2011
A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans.
Yadav, Amlendu, Pawar, Mridula, Samra, Tanvir, Banerjee, Neerja, Deepak, Desh   +4 more
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Fluconazole in combination with flucytosine in the treatment of fluconazole-resistant Candida infections [PDF]

, 2003
Two patients with renal failure and fluconazole resistant but flucytosine susceptible Candida deep infection were successfully treated with the combination of the two drugs.
VENDITTI, Mario, Pietro Martino, Corrado Girmenia   +2 more
core   +1 more source

Pulmonary Aspergillosis Treated With Oral Amphotericin B (MAT2203) in a Patient With HIV‐Related Cryptococcal Meningitis

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Graphical abstract for a case of a 26‐year‐old female with advanced HIV disease, cryptococcal meningitis, and co‐infection with pulmonary aspergillosis. Both co‐infections were successfully treated with the novel oral lipid nanocrystal formulation of amphotericin B (MAT2203).
Enock Kagimu, Elizabeth Senkoro, Jane Gakuru, Morris K. Rutakingirwa, David R. Boulware, David B. Meya, Richard Kwizera   +6 more
wiley   +1 more source

Actionable Pharmacogenomics and Essential Medicines: An Analysis of WHO and African Lists for Safer and Efficacious Drug Use

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1371-1381, May 2026.
The World Health Organization Model Essential Medicines List and African national essential medicines lists (EMLs) detail drugs intended to be consistently available within national health systems, thereby supporting clinicians and pharmacists in making evidence‐based treatment decisions.
Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Janine Scholefield, Collen Masimirembwa   +5 more
wiley   +1 more source

The Burden of Adverse Drug Reactions in Africa in the Context of Pharmacogenetics‐Based Clinical Guidelines

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1382-1390, May 2026.
Genetic variation has a significant impact on patients' response to medicines. Variations in important pharmacogenes have been evaluated in several studies and consequently led to international guidelines from clinical pharmacogenomics consortia. However, there are limited examples of these being implemented across the African continent despite the ...
Janine Scholefield, Tinashe A. Mazhindu, Mohamed Nagy, David Twesigomwe, Gaye Agesa, Collen Masimirembwa   +5 more
wiley   +1 more source

Probiotic‐based strategies in vulvovaginal candidiasis management: A comprehensive review of mechanisms and future directions

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
This review focuses on vulvovaginal candidiasis (VVC), examining its epidemiology, the pathogenesis of Candida albicans, and its relationships with vaginal microbiota. It comprehensively reviews probiotic‐based management strategies and their mechanisms of action, and concludes by discussing current limitations, challenges and future research ...
Tong Chen, Yuwei Wu, Ya Chen, Ying Li, Hui Zhao, Lei Wu, He Gao, Tong Jiang, Xiaohong Wang, Moutong Chen, Jumei Zhang, Xinqiang Xie, Tingting Liang, Qingping Wu   +13 more
wiley   +1 more source

One-Step Continuous Flow Synthesis of Antifungal WHO Essential Medicine Flucytosine Using Fluorine [PDF]

, 2017
In Africa around 625 000 mortalities per annum (20% of HIV/AIDS related deaths) are due to the affects of the Cryptococcal meningitis (CM) fungal infection. Recently, the World Health Organisation (WHO) and the Infectious Disease Society of America (IDSA)
Laurent Pichon (358645), Annelyse Conte (3633895), Graham Sandford (1951078), Rabion, A., Grenier, S., Antal Harsanyi (3633889), Conte, A., Alain Rabion (3633892), Harsanyi, A., Pichon, L., Sandford, G., Sandrine Grenier (3633886)   +11 more
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Repositioning 2‐Mercaptobenzothiazole and Sulfonamides as Antifungals Against Multidrug‐Resistant Candida albicans: In Vitro and In Silico Insights

ChemistrySelect, Volume 11, Issue 19, 20 May 2026.
This study highlights the antifungal potential of 2‐mercaptobenzothiazole (MBT) and sulfonamides against multidrug‐resistant Candida albicans. In vitro assays and molecular docking with lanosterol 14α‐demethylase (L14αDM) reveal favorable activity and binding, supporting their repositioning as promising antifungal candidates. ABSTRACT Fungal infections
Bruno A. de Oliveira, Ari Sérgio de Oliveira Lemos, Gabrielle Silva de Campos Lazzarini, Natasha Silva Mayrink, Elaine Soares Coimbra, Adilson D. da Silva, Rodrigo Luiz Fabri   +6 more
wiley   +1 more source

Cell wall damage followed by remodeling occurs during adaptation to 5-flucytosine stress. [PDF]

, 2015
A) C. glabrata KUE100 cells exposed to lyticase stress were harvested in the exponential phase of growth in the absence of stress (♦) or upon 30 min of exposure to 0.7 mg/L 5-flucytosine (■), or in the exponential phase of growth reached upon adaptation ...
Mafalda Cavalheiro (782767), Rui Santos (490726), Catarina Costa (322963), Andreia Ponte (782765), Miguel Cacho Teixeira (782769), Hiroji Chibana (30368), Pedro Pais (782766), Takashi Yaguchi (782768)   +7 more
core   +1 more source