Results 71 to 80 of about 2,218 (130)

Phenotypic and Molecular Characterization of Naganishia uzbekistanensis: Diagnostic Challenges and Antifungal Resistance Profile

Journal of Clinical Laboratory Analysis, Volume 40, Issue 12, June 2026.
The graphical abstract summarizes the laboratory characterization of Naganishia uzbekistanensis strain CY11558. The isolate shows distinct colony morphology, globular yeast cells with a fibrillar surface network under scanning electron microscopy, and a weakly positive cryptococcal antigen reaction.
Xin Fan, Xinfei Chen, Jin Li, Rongchen Dai, Pengjie Hu, Li Gu, Meng Xiao, Xiaomin Yu   +7 more
wiley   +1 more source

Repurposing the antimycotic drug flucytosine for suppression of Pseudomonas aeruginosa pathogenicity

, 2013
""Although antibiotic resistance represents a public health emergency, the pipeline of new antibiotics is running dry. Repurposing of old drugs for new clinical applications is an attractive strategy for drug development.
Facchini, Marcella, E. Frangipani, L. Leoni, LEONI, Livia, VISAGGIO, DANIELA, Bragonzi A, Visaggio D, D. Visaggio, Imperi, Francesco, F. Massai, VISCA, PAOLO, Massai F, Imperi F, Facchini M, Bragonzi, Alessandra, FRANGIPANI, EMANUELA, MASSAI, FRANCESCO, P. Visca, M. Facchini, A. Bragonzi   +19 more
core   +1 more source

Antifungal resistance of candida species isolated from HIV patients in a tertiary care hospital, Mysuru, Karnataka

Indian Journal of Dermatology, 2020
Context: Candidiasis still remains as a common opportunistic infection in patients with human immunodeficiency virus (HIV). Drug resistance has become a serious health concern because of indiscriminate usage and dosage.
Umamaheshwari Shivaswamy, M N Sumana
doaj   +1 more source

Flucytosine therapeutic monitoring: 15 years experience from the UK

, 2007
Background: There is uniform consensus that flucytosine blood concentrations should be measured to avoid toxicity and ensure adequate efficacy. Objectives and methods: The purpose of this study was to evaluate all flucytosine levels performed in a ...
C. B. Moore, Howard, S. J., D. W. Denning, Denning, D. W.; id_orcid, A. C. Pasqualotto, Pasqualotto, A. C., Moore, C. B., S. J. Howard   +7 more
core   +1 more source

Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis

mBio, 2019
Cryptococcus neoformans is an encapsulated yeast responsible for approximately a quarter of a million deaths worldwide annually despite therapy, and upwards of 11% of HIV/AIDS-related deaths, rivaling the impact of tuberculosis and malaria.
R. Lu, C. Hollingsworth, J. Qiu, A. Wang, E. Hughes, X. Xin, K. M. Konrath, W. Elsegeiny, Yoon-Dong Park, L. Atakulu, J. C. Craft, E. C. Tramont, R. Mannino, P. R. Williamson   +13 more
doaj   +1 more source

Validation of 24-Hour Flucytosine MIC Determination by Comparison with 48-Hour Determination by the Clinical and Laboratory Standards Institute M27-A3 Broth Microdilution Reference Method

, 2011
Flucytosine and itraconazole are the only antifungal agents for which the Clinical Laboratory and Standards Institute recommendations include MIC breakpoint readings at 48 h only.
Carol B. Bolden, Shawn R. Lockhart, Randall J. Kuykendall, Naureen Iqbal   +3 more
core   +1 more source

In vitro activities at pH 5.0 and pH 7.0 and in vivo efficacy of flucytosine against Aspergillus fumigatus. [PDF]

, 2008
Contains fulltext : 69799.pdf (Publisher’s version ) (Open Access)The antifungal agent flucytosine was found to be active in vitro against Aspergillus fumigatus isolates when the MIC was determined at pH 5.0 instead of pH 7.0.
Meis, J.F.G.M., Janssen, W.H.P., Mouton, J.W., Dorsthorst, D.T.A. te, Verweij, P.E.   +4 more
core   +1 more source

In vitro evaluation of antifungal combinations against neurotropic dematiaceous fungi associated with primary cerebral phaeohyphomycosis

Microbiology Spectrum
Primary cerebral phaeohyphomycosis is a life-threatening disease caused by neurotropic dematiaceous fungi. At present, there are no consensus guidelines regarding optimal antifungal therapy in such cases.
Arghadip Samaddar, Jenevi Margaret Mendonsa, Sukanya Sudhaharan, Nagarathna S, Anupma Jyoti Kindo, Anjali Shetty, Umabala Pamidimukkala   +6 more
doaj   +1 more source

In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp

, 2002
We investigated the in vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine, against Aspergillus spp.
Warn, P. A., Sharp, A., Mosquera, J., Denning, D. W.; id_orcid, Moore, C. B.   +4 more
core   +1 more source

Antifungal susceptibilities of Cryptococcus species complex isolates from AIDS and non-AIDS patients in Southeast China

Brazilian Journal of Infectious Diseases
Cryptococcus spp. are common causes of mycoses in immunocompromised patients. To determine the drug susceptibilities of clinical Cryptococcus spp. isolates, the characteristics of 61 clinical Cryptococcus spp.
Meng Li, Yong Liao, Min Chen, Weihua Pan, Lixing Weng   +4 more
doaj   +1 more source