Results 71 to 80 of about 9,329 (213)

Isolation, RP‐UHPLC‐ESI‐LIT‐Orbitrap‐MS/MS‐Based Metabolic Profiling and Anticandidal Activity of the Root and Leaf Secondary Metabolites of Monotes Kerstingii Gilg (Dipterocarpaceae)

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
This paper describes the isolation and antifungal activity of secondary metabolites from the leaves and roots of Monotes kerstingii. The distribution of these metabolites in the roots and leaves was achieved through comprehensive RP‐UHPLC‐Orbitrap‐MS and MS/MS analysis.
Sorelle Kache Fotsing, Dominique Ngnintedo, Yanick Kevin Dongmo Melogmo, Alena Soboleva, Kevine Dongmo Jumeta, Bruno Ndjakou Lenta, Fabrice Fekam Boyom, Andrej Frolov, Norbert Arnold, Ludger A. Wessjohann, Norbert Sewald, Bonaventure Tchaleu Ngadjui, Ghislain Wabo Fotso   +12 more
wiley   +1 more source

Flucytosine-fluconazole cross-resistance in purine-cytosine permease-deficient Candida lusitaniae clinical isolates: indirect evidence of a fluconazole uptake transporter

, 2003
An unusual interaction between flucytosine and fluconazole was observed when a collection of 60 Candida lusitaniae clinical isolates was screened for cross-resistance.
Noël, Thierry, Paumard, Patrick, Villard, Jean, Chastin, Christiane, François, Fabienne, Brèthes, Daniel   +5 more
core   +1 more source

Antifungal resistance of candida species isolated from HIV patients in a tertiary care hospital, Mysuru, Karnataka

Indian Journal of Dermatology, 2020
Context: Candidiasis still remains as a common opportunistic infection in patients with human immunodeficiency virus (HIV). Drug resistance has become a serious health concern because of indiscriminate usage and dosage.
Umamaheshwari Shivaswamy, M N Sumana
doaj   +1 more source

Successful Management of Candida auris Bloodstream Infection in an Elderly Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Candida auris is an emerging multidrug‐resistant pathogen frequently misidentified by conventional methods, posing diagnostic and infection‐control challenges, particularly in low‐ and middle‐income countries. We report a 74‐year‐old male in Dhaka, Bangladesh, with multiple comorbidities who developed Candidemia.
Arif Hasan Chowdhury, Tania Rahman, Nazrul Islam, Tuhin Sadique, Asif Reza Khan, Debashis Sen, Ahmed Abdullah, Dinesh Mondal, Dilruba Ahmed   +8 more
wiley   +1 more source

Liposomal flucytosine capped with gold nanoparticle formulations for improved ocular delivery

, 2016
Heba F Salem,1 Sayed M Ahmed,2 Mahmoud M Omar3 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; 2Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt ...
Salem HF, Ahmed SM, Omar MM
core  

Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis

mBio, 2019
Cryptococcus neoformans is an encapsulated yeast responsible for approximately a quarter of a million deaths worldwide annually despite therapy, and upwards of 11% of HIV/AIDS-related deaths, rivaling the impact of tuberculosis and malaria.
R. Lu, C. Hollingsworth, J. Qiu, A. Wang, E. Hughes, X. Xin, K. M. Konrath, W. Elsegeiny, Yoon-Dong Park, L. Atakulu, J. C. Craft, E. C. Tramont, R. Mannino, P. R. Williamson   +13 more
doaj   +1 more source

Biocide Response of Candida auris

Mycoses, Volume 69, Issue 3, March 2026.
ABSTRACT Candida auris is an emerging multidrug‐resistant yeast demonstrating remarkable persistence in healthcare environments, contributing to nosocomial transmission and outbreak persistence. Increasing disinfectant failure reports have raised concerns regarding infection control policies, as environmental reservoirs play central roles in its spread.
Sidre Erganis, Ali Ozturk, Elif Ayca Sahin, Ayse Kalkanci   +3 more
wiley   +1 more source

Walsh & Hoyt: Flucytosine

, 2005
Flucytosine (5-fluorocytosine) is the fluorine analogue of the naturally occurring nucleic acid pyrimidine base, cytosine. Flucytosine inhibits deoxyribonucleic acid (DNA) synthesis within fungi by acting as a noncompetitive inhibitor of thymidylate ...
Joel M. Weinstein, MD
core  

In vitro evaluation of antifungal combinations against neurotropic dematiaceous fungi associated with primary cerebral phaeohyphomycosis

Microbiology Spectrum
Primary cerebral phaeohyphomycosis is a life-threatening disease caused by neurotropic dematiaceous fungi. At present, there are no consensus guidelines regarding optimal antifungal therapy in such cases.
Arghadip Samaddar, Jenevi Margaret Mendonsa, Sukanya Sudhaharan, Nagarathna S, Anupma Jyoti Kindo, Anjali Shetty, Umabala Pamidimukkala   +6 more
doaj   +1 more source

Prediction and experimental validation of solid solutions and isopolymorphs of cytosine/5-flucytosine

, 2017
A computational search for polymorphs of cytosine, 5-flucytosine and a 1 : 1 mixture of the two substances not only rationalised the preferred packing arrangements but also enabled the finding and characterisation of cytosine/5-flucytosine solid ...
Braun, D. E., Griesser, U. J., U. J. Griesser, D. E. Braun   +3 more
core   +1 more source