Results 81 to 90 of about 2,218 (130)

Resistance of Asian Cryptococcus neoformans serotype A is confined to few microsatellite genotypes.

PLoS ONE, 2012
BackgroundCryptococcus neoformans is a pathogenic yeast that causes cryptococcosis, a life threatening disease. The prevalence of cryptococcosis in Asia has been rising after the onset of the AIDS epidemic and estimates indicate more than 120 cases per 1,
Weihua Pan, Kantarawee Khayhan, Ferry Hagen, Retno Wahyuningsih, Arunaloke Chakrabarti, Anuradha Chowdhary, Reiko Ikeda, Saad J Taj-Aldeen, Ziauddin Khan, Darma Imran, Ridhawati Sjam, Pojana Sriburee, Wanqing Liao, Kunyaluk Chaicumpar, Natnicha Ingviya, Johan W Mouton, Ilse Curfs-Breuker, Teun Boekhout, Jacques F Meis, Corné H W Klaassen   +19 more
doaj   +1 more source

Cryptococcus neoformans-Cryptococcus gattii Species Complex: an International Study of Wild-Type Susceptibility Endpoint Distributions and Epidemiological Cutoff Values for Amphotericin B and Flucytosine [PDF]

, 2012
Clinical breakpoints (CBPs) are not available for the Cryptococcus neoformans-Cryptococcus gattii species complex. MIC distributions were constructed for the wild type (WT) to establish epidemiologic cutoff values (ECVs) for C. neoformans and C.
Govender, N., Fuller, J., J. Fuller, Martins, M., Melhem, M.S., Kidd, S., M. S. C. Melhem, C. Lass-Flörl, Meis, J.F.G.M., Schell, W.A., Hagen, F., Lockhart, S.R., Pelaez, T., Chowdhary, A., Martins, M. A., M. A. Pfaller, Espinel-Ingroff, A., F. Hagen, Schell, W. A., Schell, W., Ostrosky-Zeichner, L., L. Trilles, A. Fothergill, M. Cuenca-Estrella, L. Ostrosky-Zeichner, Trilles, L., A. Espinel-Ingroff, et al., S. R. Lockhart, Fothergill, A., S. Kidd, N. Govender, Pfaller, M., E. Johnson, J. F. Meis, Melhem, M., Melhem, M. S., A. Chowdhary, Meis, J., Meis, J. F., M. A. Martins, Guarro, J., Martins, M.A., Lockhart, S., Lockhart, S. R., Lass-Florl, C., J. Turnidge, Pfaller, M.A., Pfaller, M. A., T. Pelaez, Turnidge, J., J. Guarro, Melhem, M. S. C., W. A. Schell, Cuenca-Estrella, M., Johnson, E.   +55 more
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Flucytosine for treatment of Candida albicans in H1N1-positive patient

, 2011
A 17-year-old H1N1-positive patient was successfully extubated after 25 days of ventilatory support for treatment of viral pneumonia which was complicated by empyema thoracis due to Candida albicans.
Yadav, Amlendu, Pawar, Mridula, Samra, Tanvir, Banerjee, Neerja, Deepak, Desh   +4 more
core   +1 more source

Microwave-assisted GBB-MCR modification of flucytosine for novel bicyclic-azine antifungals with dual diversity points against Aspergillus fumigatus

Discover Chemistry
The present manuscript demonstrated an efficient microwave assisted Multicomponent reaction approach in modifying the existing drug 5-fluorocytosine (Flucytosine).
Pratibha Shukla, A. K. Narula, Deepa Deswal   +2 more
doaj   +1 more source

Liposomal flucytosine capped with gold nanoparticle formulations for improved ocular delivery

, 2016
Heba F Salem,1 Sayed M Ahmed,2 Mahmoud M Omar3 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt; 2Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt ...
Salem HF, Ahmed SM, Omar MM
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Vertebral infection with Candida albicans failing caspofungin and fluconazole combination therapy but successfully treated with high dose liposomal amphotericin B and flucytosine

Medical Mycology Case Reports, 2014
A patient with Candida spondylitis failed two weeks of fluconazole combined with caspofungin, and the infection relapsed despite six weeks of liposomal amphotericin B followed by two months of fluconazole.
Line Storm, Karen R. Lausch, Maiken C. Arendrup, Klaus L. Mortensen, Eskild Petersen   +4 more
doaj   +1 more source

Antifungal susceptibility to amphotericin B, fluconazole, voriconazole, and flucytosine in Candida bloodstream isolates from 15 tertiary hospitals in Korea [PDF]

, 2012
The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.
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MIC range (μg/mL) of LIF 12560 and LIF-E10 against amphotericin B, 5-flucytosine, fluconazole, itraconazole and voriconazole.

, 2016
MIC range (μg/mL) of LIF 12560 and LIF-E10 against amphotericin B, 5-flucytosine, fluconazole, itraconazole and voriconazole.
Isabela Haddad Peron (3154302), Franqueline Reichert-Lima (3154314), Maria Luiza Moretti (3154305), Cristiane Kibune Nagasako (3154317), Angelica Zaninelli Schreiber (3154320), Luzia Lyra (3154308), Ariane Fidelis Busso-Lopes (3154311)   +6 more
core   +1 more source

The dual role of Candida glabrata Drug:H+ Antiporter CgAqr1 (ORF CAGL0J09944g) in antifungal drug and acetic acid resistance

Frontiers in Microbiology, 2013
Opportunistic Candida species often have to cope with inhibitory concentrations of acetic acid, in the acidic environment of the vaginal mucosa. Given that the ability of these yeast species to tolerate stress induced by weak acids and antifungal drugs ...
Catarina eCosta, André Sales Henriques, Carla ePires, Joana eNunes, Michiyo eOhno, Hiroji eChibana, Isabel eSá-Correia, Isabel eSá-Correia, Miguel Cacho Teixeira, Miguel Cacho Teixeira   +9 more
doaj   +1 more source

Impact of Biofilm Formation by Vaginal Candida albicans and Candida glabrata Isolates and Their Antifungal Resistance: A Comprehensive Study in Ecuadorian Women

Journal of Fungi
Candida albicans and Candida glabrata are key fungal pathogens linked to candidiasis, with rising concerns due to antifungal resistance and biofilm abilities. However, data from Latin America remains limited.
Ariana Cecibel Cedeño-Pinargote, Nicolás Renato Jara-Medina, Carlos C. Pineda-Cabrera, Darío F. Cueva, María P. Erazo-Garcia, Eduardo Tejera, António Machado   +6 more
doaj   +1 more source