Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Data-Driven Adaptive Control of Transonic Buffet via Localized Morphing Skin
Transonic shock buffet, characterized by large-amplitude self-sustained shock oscillations arising from shock wave/boundary layer interactions, poses significant challenges to aircraft handling quality and structural integrity.
Yuchen Zhang +5 more
doaj +1 more source
Superseismic Loading and Shock Polars: An Example of Fluid-Solid Coupling [PDF]
We propose a two-dimensional problem involving fluid-solid coupling where a solution is given in closed form. The upper half of the domain is modeled as an isotropic solid; the lower part as a compressible gas.
Arienti, Marco, Shepherd, Joseph E.
core +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Effects of finite strains in fully coupled 3D geomechanical simulations [PDF]
Numerical modeling of geomechanical phenomena and geo-engineering problems often involves complex issues related to several variables and corresponding coupling effects.
De Marchi, Nico +2 more
core +1 more source
Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham +7 more
wiley +1 more source
Spectral element modeling of three dimensional wave propagation in a self-gravitating Earth with an arbitrarily stratified outer core [PDF]
This paper deals with the spectral element modeling of seismic wave propagation at the global scale. Two aspects relevant to low-frequency studies are particularly emphasized.
Bermúdez +25 more
core +3 more sources
Development and Constitutive Model of Fluid–Solid Coupling Similar Materials
The Cretaceous Zhidan group (K1zh) pore fissure-confined water aquifer in Yingpanhao Coal Mine, Ordos City, China, has loose stratum structure, high porosity, strong permeability and water conductivity. In order to explore the fluid–solid coupling similar material and its constitutive model suitable for the aquifer, a kind of fluid–solid coupling ...
Baiping Li, Yunhai Cheng, Fenghui Li
openaire +1 more source
High‐temperature interactions between low‐sulfur Al‐killed Mn–B steel and MgO–C refractories (0 and 50 wt% recyclates) are studied via finger immersion tests (1600 °C). Surface‐active elements influence infiltration. MgO/CaS layer forms, along with spinel and calcium silicate.
Matheus Roberto Bellé +5 more
wiley +1 more source
Additive Gaussian Process Regression for Predictive Design of High‐Performance, Printable Silicones
A chemistry‐aware design framework for tuning printable polydimethylsiloxane (PDMS) for vat photopolymerization (VPP) is developed using additive Gaussian process (GP) modeling. Polymer network mechanics informs variable groupings, feasible formulation constraints, and interaction variables.
Roxana Carbonell +3 more
wiley +1 more source

