Results 81 to 90 of about 4,388,444 (360)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Non-Linear Creep of Spherical Container with Fluid Under Increasing Pressure

open access: yesEngineering Proceedings
This paper presents an analysis of the time-dependent response of a spherical container to internal pressure that increases over time. The wall of the container is relatively thin, in the sense that the wall thickness is negligible in comparison to the ...
Victor Rizov
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

DIETARY PRACTICES OF AEROBIC DANCERS AND BODYBUILDERS IN VHEMBE DISTRICT, LIMPOPO PROVINCE: ASSESSING THE NEED FOR NUTRITION INTERVENTION STRATEGIES

open access: yesGlobal Journal of Public Health Medicine
Introduction: Recreational sports have gained popularity in South Africa. However, the dietary practices of participants remain unknown. The study evaluated the nutrient and timing of intake of recreational sports participants in the Vhembe District (VD),
Raymond Ramashidzha   +2 more
doaj   +1 more source

Nonlinear dynamic analysis of rotating pipe conveying fluid by the finite element method

open access: yesTransport, 2003
The rotating pipe conveying fluid is considered. Non-linear (geometrical non-linearity) equation of the motion of the pipe is derived using the finite element method.
Marijonas Bogdevičius
doaj   +1 more source

The motion of ellipsoidal particles immersed in a viscous fluid

open access: yes, 1922
In both physical and biological science, we are often concerned with the properties of a fluid, or plasma, in which small particles or corpuscles are suspended and carried about by the motion of the fluid. The presence of the particles will influence the
G. B. Jeffery
semanticscholar   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

An Evaluation of Adults' Water and Fluid Consumption

open access: yesOnline Journal of Health & Allied Sciences, 2016
Aim: This study was aimed to determine the daily water and fluid consumption of health professionals. Methods: The sample included 313 subjects (female: 222, male: 91) between 22 and 49 years of age.
Hülya Yardimci   +4 more
doaj  

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