Results 51 to 60 of about 1,238,717 (284)

Characterising Fatigue Behaviour of Nodular Cast Iron Using Micromechanical Simulations [PDF]

open access: yesMATEC Web of Conferences, 2019
Elastic-plastic porous materials experience an increase in the mean void volume fraction when they are subjected to cyclic loading. This behavior is known both from the experiments and simulations in the literature.
Lukhi Mehul   +2 more
doaj   +1 more source

Acoustic analogs of two-dimensional black holes

open access: yes, 2004
We present a general method for constructing acoustic analogs of the black hole solutions of two-dimensional (2D) dilaton gravity. Because by dimensional reduction every spherically symmetric, four-dimensional (4D) black hole admits a 2D description, the
Cadoni, Mariano
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Explicit Prediction of Continental Convection in a Skillful Variable‐Resolution Global Model

open access: yesJournal of Advances in Modeling Earth Systems, 2019
We present a new global‐to‐regional model, cfvGFS, able to explicitly (without parameterization) represent convection over part of the Earth. This model couples the Geophysical Fluid Dynamics Laboratory Finite‐Volume Cubed‐Sphere Dynamical Core (FV3) to ...
Lucas M. Harris   +4 more
doaj   +1 more source

Flow-dependent fluorescence of CCVJ

open access: yesJournal of Biological Engineering, 2017
Background The molecular rotor 9-(2-Carboxy-2-cyanovinyl)julolidine (CCVJ) is presumed to have a sensitivity towards velocity or shear which is supposed to result in a change in fluorescence quantum yield. Furthermore, a previously reported photoisomeric
Markus J. Schmidt   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Recent increases in tropical cyclone intensification rates

open access: yesNature Communications, 2019
Tropical cyclones that rapidly intensify are associated with the highest forecast errors and the strongest storms. This study shows that the proportion of tropical cyclones that rapidly intensify recently increased in the Atlantic basin, and that this ...
Kieran T. Bhatia   +6 more
doaj   +1 more source

Energy Price as an Input to Fuzzy Wastewater Level Control in Pump Storage Operation

open access: yesIEEE Access, 2023
This paper presents a novel control strategy for pumps in storage tanks that accounts for fluctuations in energy prices. Storage tanks are commonly used in industrial and commercial applications to store and transport large quantities of liquids or gases.
Thiago A. M. Euzebio   +3 more
doaj   +1 more source

Critical dynamics of an isothermal compressible non-ideal fluid

open access: yes, 2012
A pure fluid at its critical point shows a dramatic slow-down in its dynamics, due to a divergence of the order-parameter susceptibility and the coefficient of heat transport.
A. Onuki   +18 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

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