Results 91 to 100 of about 112,408 (351)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Post-metamorphic fluid infiltration into granulites from the Adirondack Mountains, USA [PDF]

open access: yes
Post-metamorphic effects in the anorthosites of the Adirondacks, New York were described. Calcite-chlorite-sericite assemblages occur as veins, in disseminated form and as clots, and document retrograde fluid infiltration.
Morrison, J., Valley, John W.
core   +1 more source

Криометрические и термометрические исследования флюидных включений в кварце золоторудного месторождения Балка Широкая [PDF]

open access: yes, 2008
The investigation of fluid inclusions for the gold deposit shows the evolution of the regres-sive mineral-forming system in the completed geological cycle.
Витык, М.О.   +3 more
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Stable isotope studies on granulites from the high grade terrain of Southern India [PDF]

open access: yes
Fluid inclusion and petrologic characteristics of South India granulites and their bearing on the sources of metamorphic fluids are discussed. This paper served as a review and an introduction to the next paper by D. Jackson.
Harris, N. B. W.   +3 more
core   +1 more source

Brownian dynamics of elongated particles in a quasi-2D isotropic liquid

open access: yes, 2017
We demonstrate experimentally that the long-range hydrodynamic interactions in an incompressible quasi 2D isotropic fluid result in an anisotropic viscous drag acting on elongated particles.
Eremin, Alexey   +2 more
core   +1 more source

Fluid inclusions in reservoirs of Weixinan Sag, Beibuwan Basin

open access: yesPetroleum Exploration and Development, 2008
: To make sure the petroleum migrating direction and pool-forming model in the Weixinan sag, 4 wells were chosen to do research on fluid inclusions and petrography. The petroleum inclusions have three types: type I occurs in early cracks of quartz debris
Ping LIU   +4 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

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