Results 141 to 150 of about 118,839 (348)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Chemical and isotopic analyses of hydrocarbon-bearing fluid inclusions in olivine-rich rocks. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci, 2020
Grozeva NG   +3 more
europepmc   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Water content and nature of solutes in shallow-mantle fluids from fluid inclusions

open access: green, 2012
Maria Luce Frezzotti   +3 more
openalex   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Exceptional Concentrations of Gold Nanoparticles in 1,7 Ga Fluid Inclusions From the Kola Superdeep Borehole, Northwest Russia. [PDF]

open access: yesSci Rep, 2020
Prokofiev VY   +8 more
europepmc   +1 more source

Ultrahigh-Pressure and -Temperature Mineral Inclusions in More Crustal Mineralizations: The Role of Supercritical Fluids [PDF]

open access: gold, 2023
R Thomas   +24 more
openalex   +1 more source

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