Results 71 to 80 of about 15,097 (295)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Two-dimensional analysis of a simplified fluidic oscillator
Mechanical Engineering Journal, 2018 In order to investigate a self-excited oscillatory phenomenon of a two-dimensional confined jet with a cylinder as a downstream target, the authors conduct two-dimensional numerical analyses based on vorticity ζ and stream function ψ using a finite ...
Katsuya HIRATA +5 more
doaj +1 more source
A survey of potential applications of fluidics to spacecraft attitude control [PDF]
, 1967 Potential applications of fluidics to spacecraft attitude ...
Fuller, H. V., Jr., Garner, H. D.
core
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Time-Delay Circuits for Fluidic Oscillators and Pulse Shapers
Energies, 2019 Fluidic signals transferred between mutually communicating components of fluidic circuits are nowadays still often in the format of continuously varied value of pressure or flow rate.
Václav Tesař
doaj +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
The multifaceted roles of lysosomes in cancer
Molecular Oncology, EarlyView.Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
Fluidics: A New Tool for Controls
, 1968 This paper discusses the principles which form the bases for the phenomena usually referred to under the common heading of “Fluidics.” It explains how these phenomena can be used to obtain desired results, gives a few examples and points out some of the ...
Erich A. Farber
core +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
On the Stable-Oscillation Domain of a Simple Fluidic Oscillator
Journal of Fluid Science and Technology, 2009 A confined jet sometimes causes a self-exited oscillation due to the existence of a downstream target. In this work, the authors study this phenomenon.
Katsuya HIRATA +4 more
doaj +1 more source