Results 101 to 110 of about 14,172 (248)
Image derived input functions for cerebral PET studies [PDF]
, 2009 Lammertsma, A.A. [Promotor]Boellaard, R.
Mourik, J.E.M.
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Antagonism of triazolam self-administration in rhesus monkeys responding under a progressive-ratio schedule: In vivo apparent pA2 analysis. [PDF]
, 2016 BACKGROUND: Conventional benzodiazepines bind non-selectively to GABAA receptors containing α1, α2, α3, and α5 subunits (α1GABAA, α2GABAA, α3GABAA, and α5GABAA receptors, respectively), and the role of these different GABAA receptor subtypes in the ...
Cook, James M +5 more
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Sedation reversal with flumazenil? [PDF]
British Dental Journal, 2002 Objective To study the post-operative cognitive and psychomotor recovery from midazolam conscious sedation, after reversal with the benzodiazepine antagonist flumazenil over a prolonged recovery period. Design A prospective, double-blind, randomised, crossover trial.
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Altered expression of α3-containing GABAA receptors in the neocortex of patients with focal epilepsy [PDF]
, 2017 Impaired transmission in GABAergic circuits is thought to contribute to the pathogenesis of epilepsy. Although it is well established that major reorganization of GABAA receptor subtypes occurs in the hippocampus of patients with medically refractory ...
André, Véronique M. +6 more
core
Image Derived Input Functions: Effects of Motion on Tracer Kinetic Analyses [PDF]
, 2010 Purpose: To quantify the effects of motion affected image-derived input functions (IDIF) on the outcome of tracer kinetic analyses. Procedures: Two simulation studies, one based on high and the other on low cortical uptake, were performed.
Boellaard, Ronald +3 more
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Benzodiazepine intoxication treated with flumazenil (Anexate, RO 15–1788) [PDF]
, 1988 Lone Knudsen +5 more
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Nature's Brewery to Bedtime: The Role of Hops in GABAA Receptor Modulation and Sleep Promotion [PDF]
Doctoral Dissertation University of Turku. ISBN: 978-951-29-9577-6
(2023)Insomnia often requires pharmacological interventions, with benzodiazepines and Z-drugs enhancing GABA's inhibitory effects by stabilizing GABAA receptor chloride ion channels. Prolonged use, however, raises dependency and cognitive concerns. Humulus lupulus (hops) is gaining attention as a natural relaxant and sleep aid, potentially modulating GABAA ...
arxiv
Flumazenil, naloxone and the ‘coma cocktail’ [PDF]
British Journal of Clinical Pharmacology, 2015 Flumazenil and naloxone are considered to be pharmacologically ideal antidotes. By competitive binding at the molecular target receptors, they are highly specific antagonists of two important drug classes, the benzodiazepines and opioids, respectively.
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