Results 31 to 40 of about 19,781 (210)

Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome

Memorias do Instituto Oswaldo Cruz, 1997
A longitudinal study was performed with sera and urine of patients with acquired immune deficiency syndrome (AIDS), taken before, during and after clinically Toxoplasma infection. The tested patients were followed for an average of two years.
Alberto Fachado, Lisset Fonseca, Luis Fonte, Esteban Alberti, Raymundo Cox, Frank Bandera   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Evaluation of the Acridine Orange Fluorescence Technique and the Indirect Fluorescent Antibody as Diagnostic Tests for Tropical Theileriosis [PDF]

Veterinary World, 2011
This study was carried out to evaluate the use of acridine orange fluorescence technique on blood slides as a rapid diagnostic test for tropical theileriosis in comparison with the Giemsa-stained thin blood film technique.
Mahmoud, O. H., Omer, O.M. and Al-Sadrani, A.A.   +4 more
doaj  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Antibody elution with 2-me/SDS solution: Uses for multi-layer immunohistochemical analysis of wholemount preparations of human colonic myenteric plexus

Heliyon
Indirect immunofluorescence is usually restricted to 3-5 markers per preparation, limiting analysis of coexistence. A solution containing 2-mercaptoethanol and sodium dodecyl sulfate (2-ME/SDS) can elute indirect immunofluorescence labelling (i.e ...
Adam Humenick, M.E. Johnson, B.N. Chen, M. Wee, D.A. Wattchow, M. Costa, P.G. Dinning, S.J.H. Brookes   +7 more
doaj   +1 more source

A novel method for isolation and flow cytometry analysis of intraepithelial lymphocytes from colon biopsies

JDS Communications, 2023
Investigating the immune responses of the intestine in response to different insults is predominantly limited to indirect methods such as circulating markers of intestinal health or gene expression from dissections.
K. Lamers, M.A. Steele, L.R. Cangiano
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

SEROEPIDEMIOLOGICAL STUDY OF P. VIVAX MALARIA WITH SUSPECTED LONG INCUBATION IN IRAN [PDF]

Iranian Journal of Public Health, 1976
P. vivax malaria with suspected long incubation have been frequently observed mostly in the northwest part of Iran in the course of Malaria Control and Malaria Eradication Operations.
Gh. H. Edrissian, F. Naimi, A. Afshar   +2 more
doaj   +1 more source

Frequency of ANA/DFS70 autoantibodies in Colombian patients with undifferentiated connective tissue disease

Reumatismo, 2022
The objective was to describe the clinical characteristics and the frequency of the ANA/DFS70 autoantibodies in patients affected by undifferentiated connective tissue disease (UCTD) in a tertiary hospital in Colombia.
D. Rincón-Riaño, D.G. Fernández-Ávila, D. Acero-Molina, J.M. Bello Gualtero , C. Romero-Sánchez   +4 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source