Results 31 to 40 of about 53,983 (253)

Toxoplasma gondii Antigenuria in Patients with Acquired Immune Deficiency Syndrome

open access: yesMemorias do Instituto Oswaldo Cruz, 1997
A longitudinal study was performed with sera and urine of patients with acquired immune deficiency syndrome (AIDS), taken before, during and after clinically Toxoplasma infection. The tested patients were followed for an average of two years.
Alberto Fachado   +5 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

A novel method for isolation and flow cytometry analysis of intraepithelial lymphocytes from colon biopsies

open access: yesJDS Communications, 2023
Investigating the immune responses of the intestine in response to different insults is predominantly limited to indirect methods such as circulating markers of intestinal health or gene expression from dissections.
K. Lamers, M.A. Steele, L.R. Cangiano
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

SEROEPIDEMIOLOGICAL STUDY OF P. VIVAX MALARIA WITH SUSPECTED LONG INCUBATION IN IRAN [PDF]

open access: yesIranian Journal of Public Health, 1976
P. vivax malaria with suspected long incubation have been frequently observed mostly in the northwest part of Iran in the course of Malaria Control and Malaria Eradication Operations.
Gh. H. Edrissian   +2 more
doaj   +1 more source

Antibody elution with 2-me/SDS solution: Uses for multi-layer immunohistochemical analysis of wholemount preparations of human colonic myenteric plexus

open access: yesHeliyon
Indirect immunofluorescence is usually restricted to 3-5 markers per preparation, limiting analysis of coexistence. A solution containing 2-mercaptoethanol and sodium dodecyl sulfate (2-ME/SDS) can elute indirect immunofluorescence labelling (i.e ...
Adam Humenick   +7 more
doaj   +1 more source

Frequency of ANA/DFS70 autoantibodies in Colombian patients with undifferentiated connective tissue disease

open access: yesReumatismo, 2022
The objective was to describe the clinical characteristics and the frequency of the ANA/DFS70 autoantibodies in patients affected by undifferentiated connective tissue disease (UCTD) in a tertiary hospital in Colombia.
D. Rincón-Riaño   +4 more
doaj   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

The prevalence of Toxoplasma infection in hospitalized patients in selected hospitals of Kerman. [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2000
Toxoplasmosis is a disease caused by a ubiquitous,obilgate intrace;;ular protozoan"Toxoplasma gondii".the present study was undertaken to determine the prevalence of Toxoplasma infection in Kerman province of Iran.Atotal of 690 bllod samples,collected ...
H Keshavarz, S Mamishi, H Daneshvar
doaj  

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