Results 41 to 50 of about 36,085 (261)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

ANTIGENIC AND MOLECULAR IDENTIFICATION OF SOME VIRUSES CAUSING RESPIRATORY DISORDER IN CALVES

Assiut Veterinary Medical Journal, 2009
  Bovine parainfluenza virus Type 3 (BPI3) and bovine respiratory syncytial virus (BRSV), are ubiquitous respiratory pathogens of cattle, which contribute to causation of bovine respiratory disease complex.
HANAA A.M. GHONIEM, NAHED A. MAHMOUD, OMAYMA A. SHEMIES, JEHAN A. GAFER   +3 more
doaj   +1 more source

A conglutination test for rapid detection of antibodies against Babesia bigemina [PDF]

Pesquisa Veterinária Brasileira, 2000
A rapid conglutination test (RCT) with performance comparable to the indirect fluorescent antibody technique (IFAT) was developed to detect antibodies against Babesia bigemina (B. bigemina-RCT). The B.
Claudio R. Madruga, Raul H. Kessler, Maria A. M. Schenk, Midori Miguita   +3 more
doaj   +1 more source

Evaluation of Two Types of Infectious Mononucleosis Antigen Slides by the Indirect Fluorescent-Antibody Technique [PDF]

Applied Microbiology, 1973
The efficiency of two types of antigen slides was compared by using the indirect fluorescent-antibody technique. Fifty sera from infectious mononucleosis patients were tested concurrently on the two sets of slides for antibody to Epstein-Barr virus. The indirect fluorescent-antibody serum titer readings from the epoxy slides were either equal to or ...
L A, Dye, P M, Feorino
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Human cryptosporidiosis: detection of specific antibodies in the serum by an indirect immunofluorescence

Revista de Saúde Pública, 1996
Cryptosporidium sp., a coccidian parasite usually found in the faeces of cattle, has been recently implicated as an agent of human intestinal disease, mainly in immunocompromised patients.
Braz Lúcia M.A., Amato Neto Vicente, Ferrari Clara I.L., Palhares Maria C.A., Amato Valdir S., Santos Márcia T.F., Marques Heloísa H.S., Vallada Marcelo, Nakanishi Laura S.S., Andrade Júnior Heitor F.   +9 more
doaj  

The prevalence of Toxoplasma infection in hospitalized patients in selected hospitals of Kerman. [PDF]

Journal of Kerman University of Medical Sciences, 2000
Toxoplasmosis is a disease caused by a ubiquitous,obilgate intrace;;ular protozoan"Toxoplasma gondii".the present study was undertaken to determine the prevalence of Toxoplasma infection in Kerman province of Iran.Atotal of 690 bllod samples,collected ...
H Keshavarz, S Mamishi, H Daneshvar
doaj  

Indirect fluorescent-antibody technique for serological diagnosis of La Crosse (California) virus infections [PDF]

Journal of Clinical Microbiology, 1982
A clinically relevant indirect fluorescent-antibody technique (IFA) was developed for the serological diagnosis of La Crosse virus infections. The IFA (67%) was as sensitive as the hemagglutination inhibition (58%) and neutralization (58%) tests in the detection of antibodies in acute-phase specimens.
B J, Beaty, J, Casals, K L, Brown, C B, Gundersen, D, Nelson, J T, McPherson, W H, Thompson   +6 more
openaire   +2 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

DIRECT AND INDIRECT FLUORESCENT-ANTIBODY TECHNIQUES FOR THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA GROUP OF AGENTS [PDF]

Journal of Bacteriology, 1963
Ross, MartinR. (Connecticut State Department of Health, Hartford)and Earle K. Borman. Direct and indirect fluorescent-antibody techniques for the psittacosis-lymphogranuloma venereum-trachoma group of agents. J. Bacteriol.85:851–858. 1963.—Direct and indirect fluorescent-antibody (FA) techniques were developed for the detection of group antigen in ...
M R, ROSS, E K, BORMAN
openaire   +2 more sources