Reduced placental telomere length during pregnancies complicated by intrauterine growth restriction. [PDF]
OBJECTIVES: Recent studies have shown that telomere length was significantly reduced in placentas collected at delivery from pregnancies complicated by intrauterine growth restriction secondary to placental insufficiency.
Jérôme Toutain +13 more
doaj +1 more source
Painting of human chromosomes with probes generated from hybrid cell lines by PCR with Alu and L1 primers [PDF]
Specific amplification of human sequences of up to several kb length has recently been accomplished in man-hamster and man-mouse somatic hybrid cell DNA by IRS-PCR (interspersed repetitive sequence — polymerase chain reaction).
Cremer, Thomas +2 more
core +1 more source
A method for nucleic acid hybridization to isolated chromosomes in suspension [PDF]
A procedure was developed to provide differential fluorescent staining of metaphase chromosomes in suspension following nucleic acid hybridization. For this purpose metaphase chromosomes were isolated from a Chinese hamster x human hybrid cell line ...
Bier, Frank +5 more
core +1 more source
A Study of Epidermal Growth Factor Receptor 2 (HER2/neu) Expression in Endoscopic Biopsies and Gastrectomy Specimens of Gastric Adenocarcinomas [PDF]
Introduction: Gastric carcinoma (GC) is the fourth most commonly diagnosed cancer and has poor prognosis, since most of the patients present with advanced disease and the therapeutic options available are very few.
Sheela Devi CS, Soumya BU, Suchitha S
doaj +1 more source
Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla [PDF]
The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined ...
Bigoni, F. +5 more
core +1 more source
Identification and characterization of satellite DNAs in Poa L.
Background Poa L. is a large genus of grass in Gramineae, among which P. pratensis is widely cultivated as turf and forage. Satellite DNA is the main components of the plant genome.
Linna Wei +6 more
doaj +1 more source
Fluorescence In Situ Hybridization Method for Co-Localization of mRNA and GFP
Co-localization studies using green fluorescent protein (GFP) and fluorescence immunohistochemistry have become commonplace. However, co-localization studies using GFP and mRNA in situ hybridization are rare, in large part because typical in situ ...
Anthony A. Oliva, John W. Swann
doaj +1 more source
Exclusive neuronal expression of SUCLA2 in the human brain [PDF]
SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia ...
A Kowluru +55 more
core +2 more sources
In Situ Hybridization Status of 568 Cases of HER2 Equivocal Breast Cancer
Objective To compare the differences between 2013 and 2018 ASCO/CAP HER2 testing guidelines in 568 immunohistochemical HER2 equivocal breast cancer patients and to analyze the accuracy and deficiency of dual-color silver enhanced in-situ hybridization ...
JIANG Yi'na +3 more
doaj +1 more source
Programmable in situ amplification for multiplexed imaging of mRNA expression [PDF]
In situ hybridization methods enable the mapping of mRNA expression within intact biological samples. With current approaches, it is challenging to simultaneously map multiple target mRNAs within whole-mount vertebrate embryos, representing a significant
A Raj +35 more
core +2 more sources

