Results 31 to 40 of about 158,410 (292)

Reduced placental telomere length during pregnancies complicated by intrauterine growth restriction. [PDF]

open access: yesPLoS ONE, 2013
OBJECTIVES: Recent studies have shown that telomere length was significantly reduced in placentas collected at delivery from pregnancies complicated by intrauterine growth restriction secondary to placental insufficiency.
Jérôme Toutain   +13 more
doaj   +1 more source

Painting of human chromosomes with probes generated from hybrid cell lines by PCR with Alu and L1 primers [PDF]

open access: yes, 1990
Specific amplification of human sequences of up to several kb length has recently been accomplished in man-hamster and man-mouse somatic hybrid cell DNA by IRS-PCR (interspersed repetitive sequence — polymerase chain reaction).
Cremer, Thomas   +2 more
core   +1 more source

A method for nucleic acid hybridization to isolated chromosomes in suspension [PDF]

open access: yes, 1987
A procedure was developed to provide differential fluorescent staining of metaphase chromosomes in suspension following nucleic acid hybridization. For this purpose metaphase chromosomes were isolated from a Chinese hamster x human hybrid cell line ...
Bier, Frank   +5 more
core   +1 more source

A Study of Epidermal Growth Factor Receptor 2 (HER2/neu) Expression in Endoscopic Biopsies and Gastrectomy Specimens of Gastric Adenocarcinomas [PDF]

open access: yesNational Journal of Laboratory Medicine, 2016
Introduction: Gastric carcinoma (GC) is the fourth most commonly diagnosed cancer and has poor prognosis, since most of the patients present with advanced disease and the therapeutic options available are very few.
Sheela Devi CS, Soumya BU, Suchitha S
doaj   +1 more source

Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla [PDF]

open access: yes, 1992
The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined ...
Bigoni, F.   +5 more
core   +1 more source

Identification and characterization of satellite DNAs in Poa L.

open access: yesMolecular Cytogenetics, 2020
Background Poa L. is a large genus of grass in Gramineae, among which P. pratensis is widely cultivated as turf and forage. Satellite DNA is the main components of the plant genome.
Linna Wei   +6 more
doaj   +1 more source

Fluorescence In Situ Hybridization Method for Co-Localization of mRNA and GFP

open access: yesBioTechniques, 2001
Co-localization studies using green fluorescent protein (GFP) and fluorescence immunohistochemistry have become commonplace. However, co-localization studies using GFP and mRNA in situ hybridization are rare, in large part because typical in situ ...
Anthony A. Oliva, John W. Swann
doaj   +1 more source

Exclusive neuronal expression of SUCLA2 in the human brain [PDF]

open access: yes, 2013
SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia ...
A Kowluru   +55 more
core   +2 more sources

In Situ Hybridization Status of 568 Cases of HER2 Equivocal Breast Cancer

open access: yesZhongliu Fangzhi Yanjiu, 2019
Objective To compare the differences between 2013 and 2018 ASCO/CAP HER2 testing guidelines in 568 immunohistochemical HER2 equivocal breast cancer patients and to analyze the accuracy and deficiency of dual-color silver enhanced in-situ hybridization ...
JIANG Yi'na   +3 more
doaj   +1 more source

Programmable in situ amplification for multiplexed imaging of mRNA expression [PDF]

open access: yes, 2010
In situ hybridization methods enable the mapping of mRNA expression within intact biological samples. With current approaches, it is challenging to simultaneously map multiple target mRNAs within whole-mount vertebrate embryos, representing a significant
A Raj   +35 more
core   +2 more sources

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