Results 161 to 170 of about 79,190 (262)

Suppression of Retinal Neovascularisation by Tetrahedral Framework Nucleic Acids‐Resveratrol Via Dual Anti‐Angiogenesis and Anti‐Inflammation

open access: yesCell Proliferation, EarlyView.
Resveratrol‐loaded tetrahedral framework nucleic acids (tFNAs‐RSV) enable concurrent anti‐angiogenic and anti‐inflammatory therapy, enhancing ocular delivery and bioactivity. In hypoxia‐induced retinal neovascularisation, tFNAs‐RSV reduce neovascular lesions, vascular leakage and inflammatory infiltration by suppressing HIF‐1, p38 MAPK and NF‐κB p65 ...
Yili Jin   +7 more
wiley   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

open access: yesCell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu   +15 more
wiley   +1 more source

Meta-analysis of stage-specific <i>Calanus finmarchicus</i> vertical distribution in relation to hydrography and chlorophyll in the North Atlantic. [PDF]

open access: yesJ Plankton Res
Chamorro E   +14 more
europepmc   +1 more source

A Noncanonical Protein Degradation Pathway That Regulates Germ Cell Maintenance

open access: yesCell Proliferation, EarlyView.
SENP8 regulates a non‐canonical NEDD8‐dependent pathway to stabilize STAT1, promote CCL2/CCL5 transcription, and maintain germ cell proliferation and migration.
Meng Liu   +11 more
wiley   +1 more source

The Great Dividing Range as a driver of genetic divergence in a low‐dispersing dragonfly

open access: yesEcological Entomology, EarlyView.
Population genomic analyses revealed low genetic differentiation and no discrete population structure across the Great Dividing Range, indicating widespread gene flow in Synthemis eustalacta. Genetic divergence was associated with environmental gradients, elevation and landscape resistance rather than geographic distance, supporting isolation by ...
Aaron M. Goodman   +20 more
wiley   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

open access: yesThe FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney   +10 more
wiley   +1 more source

Genome characterization of <i>Salmonella enterica</i> serovar Enteritidis phage SESL from a Malaysian hot spring salt lick. [PDF]

open access: yesMicrobiol Resour Announc
Tan YF   +6 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy