Results 181 to 190 of about 9,550 (296)

Fragment Edges Benefit a Common Predator of Pollinators via Bottom‐Up Effects

open access: yesIntegrative Zoology, EarlyView.
This study investigated the hypotheses regarding the effects of habitat fragmentation on spider biomass and causing bottom‐up or top‐down effects on multi‐trophic relationships. ABSTRACT Defaunation following habitat fragmentation typically threatens predators at higher trophic levels, which further alter prey and plants via top‐down effects.
Wenlong Zhou   +7 more
wiley   +1 more source

Gut Microbiota Analysis and Comparison in Forest Musk Deer (Moschus berezovskii) of Different Ages and Musk‐Secreting Periods

open access: yesIntegrative Zoology, EarlyView.
Metagenomic sequencing was used to analyze fecal microbiota of captive male forest musk deer (FMD) from the Sichuan Institute of Musk Deer Breeding across ages and musk‐secreting periods. Gut microbiota was generally stable and dominated by Firmicutes, while age and musk secretion shaped microbial composition and function, with musk collection linked ...
Jiuyan Jiang   +17 more
wiley   +1 more source

Chromatin Accessibility Profiling of the Canine Brain Reveals Regulatory Programs Associated With Dog‐Wolf Divergence and Human Psychiatric Risk

open access: yesIntegrative Zoology, EarlyView.
The dog is a valuable model for studying social behavior and neuropsychiatric disease. We generated an ATAC‐seq atlas of 7 brain regions and pituitary from 4 beagles, identifying 251,492 CREs. Integrating dog‐wolf divergence revealed tissue‐specific CREs overlapping divergent loci, including neuronal and neuroendocrine genes.
Biao Deng   +15 more
wiley   +1 more source

Seasonal and Regional Dietary Heterogeneity Is Associated With Gut Microbiota Differentiation in Przewalski's Gazelle (Procapra przewalskii)

open access: yesIntegrative Zoology, EarlyView.
Seasonal and regional dietary variation in Przewalski's gazelle was linked to coordinated changes in gut microbiota, functional pathways, and fecal metabolites. Winter diets featured Poaceae, Cyperaceae, and Iridaceae, whereas summer diets shifted toward forb families.
Jingjie Zhang   +4 more
wiley   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

open access: yesAndrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz   +12 more
wiley   +1 more source

Differential Sperm DNA Methylation Profiles in Healthy Men With High Versus Low Adherence to the Mediterranean Diet in the Led‐Fertyl Study

open access: yesAndrology, EarlyView.
ABSTRACT Background Diet is known to play an essential role not only in sperm quality but also in offspring health, likely mediated through the sperm epigenome. Moreover, one of the main components of the Mediterranean diet (MedDiet) (i.e., nuts) have shown to impact sperm DNA methylation patterns.
Rashmi Agarwal   +10 more
wiley   +1 more source

Brain metastasis‐associated fibroblasts shape the tumour microenvironment to enhance cancer cell invasion

open access: yesBrain Pathology, EarlyView.
Brain metastasis‐associated fibroblasts are active stromal components of the metastatic niche characterised by extracellular matrix remodelling and production of pro‐migratory mediators. They promote monocyte and cancer cell migration and enhance cancer cell invasion while having no growth‐promoting effect on cancer cells.
Barbora Výmolová   +19 more
wiley   +1 more source

PTEN homozygous deletion is a negative prognostic factor in tumor treating fields‐treated glioblastoma, IDH wildtype patients

open access: yesBrain Pathology, EarlyView.
In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles   +15 more
wiley   +1 more source

Rifaximin ameliorates memory impairment and Alzheimer's pathological changes in APP/PS1 mice associated with changes in the gut microbiome–bile acids–serum metabolites networks

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Modifying the brain–gut–microbiota axis has emerged as a promising therapeutic strategy against Alzheimer's disease (AD). Whether rifaximin, a non‐absorbed and non‐systemic antibiotic, can be applied to the treatment of AD remains unexplored.
Di Wu   +7 more
wiley   +1 more source

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