Results 171 to 180 of about 79,190 (262)

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

The FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki, Timothy D. Niepokny, Tina Khalilzadehsabet, Elizabeth Dumais, Nicolas Flamand, Vincenzo Di Marzo, Eric M. Mintz, Cristoforo Silvestri   +7 more
wiley   +1 more source

De novo whole genome assembly of the globally invasive green shore crab Carcinus maenas (Linnaeus, 1758) via long-read Oxford Nanopore MinION sequencing. [PDF]

J Hered
Brons JK, Hackl T, Iacovelli R, Haslinger K, Lequime S, van der Meij SET.   +5 more
europepmc   +1 more source

TRIM32 controls timely cell cycle exit in muscular differentiation through downregulation of c‐Myc mRNA

The FEBS Journal, EarlyView.
Trim32 regulates the transition from proliferation to differentiation in C2C12 cells after myogenic induction. We found that, at the onset of differentiation, Trim32 destabilizes c‐Myc mRNA, promotes cell cycle exit, and enables normal myotube formation.
Lu Xiong, Elisa Lazzari, Sabrina Pacor, Simeone Dal Monego, Erica Piovesan, Danilo Licastro, Germana Meroni   +6 more
wiley   +1 more source

Direct interaction between phosphotransferase LpxT and ArnT modulates polymyxin B resistance in <i>Pseudomonas aeruginosa</i>. [PDF]

Microbiol Spectr
Bai Y, Zhao Y, Yuan Y, Bai F, Cheng Z, Wu W, Ha U-H, Jin S, Jin Y.   +8 more
europepmc   +1 more source

Blocking protein quality control degradation leads to structural stabilization of DHFR indel variants

The FEBS Journal, EarlyView.
Blocking protein quality control degradation by deleting the E3 ligases Ubr1 or San1 stabilizes many DHFR insertion and deletion variants that are otherwise partially unfolded. These hypomorphic variants regain folding at lower temperatures or upon methotrexate binding, revealing that PQC degradation can remove proteins that are still functionally ...
Sven Larsen‐Ledet, Caroline H. Suhr, Sarah Gersing, Celeste M. Hackney, Amelie Stein, Kaare Teilum, Rasmus Hartmann‐Petersen   +6 more
wiley   +1 more source

Metagenomes and metagenome-assembled genomes from microbial communities in a biological nutrient removal plant operated at Hamptons Road Sanitation District (HRSD) with high and low dissolved oxygen conditions. [PDF]

Microbiol Resour Announc
Enuh BM, Myers KS, Bott C, Klaus S, McCullough K, McIntosh L, Beach N, Young M, Donohue TJ, Noguera DR.   +9 more
europepmc   +1 more source

An Ex Vivo Pharmacodynamic Study of KN057, a Tissue Factor Pathway Inhibitor Neutralizing Antibody, in Plasma Samples From Patients With Haemophilia or VWD3

Haemophilia, EarlyView.
ABSTRACT Introduction Tissue factor pathway inhibitor (TFPI), a key regulator of tissue factor‐initiated coagulation through FXa‐dependent inhibition of the tissue factor‐FVIIa complex, has emerged as a promising target for restoring thrombin generation.
Mankai Ju, Feng Xue, Wei Sun, Fang Li, Ting Xu, Renchi Yang   +5 more
wiley   +1 more source

Draft genome sequence of soil isolate <i>Paenibacillus caseinilyticus</i> KO2 as a potential candidate for acetaminophen removal. [PDF]

Microbiol Resour Announc
Waghmode MS.
europepmc   +1 more source

Fine‐scale genetic structure in co‐operatively breeding Palmchats (Dulus dominicus) suggests mixed kinship in compound nests

Ibis, EarlyView.
Fine‐scale genetic structure in animal populations can create opportunities for both kin‐directed co‐operation and kin competition. Knowledge of kinship is therefore key to understanding the selective pressures shaping sociality as well as the effects of social behaviour on local genetic structure.
Joshua B. LaPergola, Gavin M. Leighton, Christina Riehl   +2 more
wiley   +1 more source

Complete genome sequence of <i>Escherichia coli</i> phage vB_EcoP_EcoN5 isolated from Magdalena River, Atlántico, Colombia. [PDF]

Microbiol Resour Announc
Lozano-Solano D, Arquez-Mendoza M, Quiñones-Vásquez S, Florez-Osorio C, Quiroz N, Solano C, Acosta-Hoyos AJ.   +6 more
europepmc   +1 more source