Results 81 to 90 of about 94,119 (260)

Molecular Characterization of Plasmid-Mediated Quinolone Resistance Genes in Multidrug-Resistant Isolated From Wastewater Generated From the Hospital Environment

Environmental Health Insights
Aim: This study investigated the carriage of Plasmid-Mediated Quinolone Resistance (PMQR) genes in fluoroquinolone-resistant Escherichia coli recovered from wastewater generated by healthcare institutions.
Omowunmi A. Banjo, Abimbola O. Adekanmbi, Oluwatimileyin J. Akinbola, Benjamin T. Thomas, Olusolape A. F. Ilusanya   +4 more
doaj   +1 more source

In-vitro Antibacterial Evaluation of Some Fluoroquinolone Derivatives Against Food Borne Bacteria [PDF]

Journal of Sciences, Islamic Republic of Iran, 2016
Food poisoning has been emerged as a worldwide health issue and related illness in both developed and developing countries confirms its significance as an important public health priority.In vitro antibacterialevaluationof nine fluoroquinolone ...
N. Shariatifar, M. Rezaei, M. Sayadi, M. H. Moshafi, M. Saeedi, N. Mohammadhosseini, S. Moghimi, A. Foroumadi   +7 more
doaj  

Old Drugs with New Tricks: Efficacy of Fluoroquinolones to Suppress Replication of Flaviviruses

Viruses, 2020
Repurposing FDA-approved compounds could provide the fastest route to alleviate the burden of disease caused by flaviviruses. In this study, three fluoroquinolones, enoxacin, difloxacin and ciprofloxacin, curtailed replication of flaviviruses Zika (ZIKV),
Stacey L. P. Scroggs, Christy C. Andrade, Ramesh Chinnasamy, Sasha R. Azar, Erin E. Schirtzinger, Erin I. Garcia, Jeffrey B. Arterburn, Kathryn A. Hanley, Shannan L. Rossi   +8 more
doaj   +1 more source

Otitis in pet guinea pigs: Causes, clinical signs, treatment and outcomes

Veterinary Record, EarlyView.
Abstract Background Otitis is a major disease impacting both pet guinea pigs and laboratory guinea pigs that are used as models in human otological studies. Methods Medical records from two veterinary clinics were retrospectively reviewed to identify guinea pigs diagnosed with computed tomography (CT)‐confirmed otitis between 2014 and 2023.
Patricia Muffat‐es‐Jacques, Mathilde Charrasse, Paul Raymond, Minh Huynh, Thomas Coutant, Charly Pignon   +5 more
wiley   +1 more source

Genome-wide antibiotic-CRISPRi profiling identifies LiaR activation as a strategy to resensitize fluoroquinolone-resistant Streptococcus pneumoniae

Nature Communications
Streptococcus pneumoniae is a human pathogen that has become increasingly resistant to synthetic fluoroquinolone antibiotics that target bacterial topoisomerases.
Bevika Sewgoolam, Kin Ki Jim, Vincent de Bakker, Florian P. Bock, Paddy S. Gibson, Jan-Willem Veening   +5 more
doaj   +1 more source

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

Veterinary Record, EarlyView.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker, Dan O'Neill, Huw Stacey, Dave Brodbelt   +3 more
wiley   +1 more source

PK-PD Analysis of Marbofloxacin against Streptococcus suis in Pigs

Frontiers in Pharmacology, 2017
Marbofloxacin is a fluoroquinolone antibiotic and highly effective treatment for respiratory diseases. Here we aimed to evaluate the ex vivo activity of marbofloxacin against Streptococcus suis in pig serum, as well as the optimal dosages scheme for ...
Zhixin Lei, Zhixin Lei, Qianying Liu, Qianying Liu, Bing Yang, Bing Yang, Haseeb Khaliq, Jiyue Cao, Jiyue Cao, Qigai He   +9 more
doaj   +1 more source

Relative and Absolute Risk of Tendon Rupture with Fluoroquinolone and Concomitant Fluoroquinolone/Corticosteroid Therapy:Population-Based Nested Case-Control Study [PDF]

, 2019
Background and Objective: Tendon rupture can result from fluoroquinolone exposure. The objective of this study was to quantify relative and absolute risk and determine how risk is affected by timing of exposure.Methods: The UK Health Improvement Network ...
Kurz, Xavier, McGettigan, Patricia, Morales, Daniel R., Pacurariu, Alexandra, Pinheiro, Luis, Slattery, Jim   +5 more
core   +3 more sources

Belgian bovine veterinarian practices and opinions on udder health‐related antimicrobial use and services

Veterinary Record, EarlyView.
Abstract Background Changing legislation regarding antimicrobial consumption (AMC) forces Flemish bovine veterinary practitioners (BVP) to rethink their business models and shift their on‐farm practices from curative to preventive. However, little is known about their current practices and opinions regarding antibiotic stewardship, mastitis treatment ...
Lien Creytens, Sofie Piepers, Sarne De Vliegher   +2 more
wiley   +1 more source

Advances in the Synthesis and Biological Applications of Enoxacin-Based Compounds

Biomolecules
A comprehensive review of advances in the synthesis and biological applications of enoxacin (1, referred to as ENX)-based compounds is presented. ENX, a second-generation fluoroquinolone (FQ), is a prominent 1,8-naphthyridine containing compounds studied
Garba Suleiman, Nabil El Brahmi, Gérald Guillaumet, Saïd El Kazzouli   +3 more
doaj   +1 more source