Results 231 to 240 of about 5,793,605 (328)

Delafloxacin suppresses DEPDC1 expression and induces G2/M arrest in non‐small cell lung cancer cells: A drug repurposing study

Smart Molecules, Volume 4, Issue 3, September 2026.
This study presents Delafloxacin repurposed as a DEPDC1‐targeting therapeutic aiming to suppress lung cancer progression. It highlights a novel strategy for lung cancer treatment with potential clinical applications. Abstract Emerging evidence highlights the oncogenic role of the Dishevelled, Egl‐10, and Pleckstrin domains containing 1 (DEPDC1) gene in
Noman Ali, Farishta Shafiq, Mishal Iftikhar, Muhammad Shahzad Zafar, Muhammad Shoaib   +4 more
wiley   +1 more source

Development of a point-of-care dual one-step recombinase-aided PCR assay for rapid identification of <i>Mycobacterium tuberculosis gyrA</i> mutations conferring fluoroquinolone resistance. [PDF]

Front Microbiol
Liu X, Peng K, Li Y, Jiao S, Wu J, Zhang D, Gao S, Xiang Y, Ren J, Ma Q, Li X, Zhao Z, Han Z, Shen X, Ma X, Tie Y.   +15 more
europepmc   +1 more source

Multiplex PCR to Diagnose Gastrointestinal Infections: Key Limitations in Interpretation

United European Gastroenterology Journal, Volume 14, Issue 7, September 2026.
ABSTRACT Multiplex polymerase chain reaction (PCR) panels are increasingly used for the evaluation of acute diarrhea, providing rapid and sensitive detection of a broad range of enteric pathogens. However, their widespread adoption has created important interpretive challenges for clinicians.
Giannoula S. Tansarli, Ferric C. Fang
wiley   +1 more source

Antimicrobial Resistance in Selected <i>Enterobacteriaceae</i> from Broilers and Their Environment: ESBL, AmpC, Carbapenemases, Colistin, and Fluoroquinolone Resistance-A Systematic Review and Meta-Analysis. [PDF]

Antibiotics (Basel)
Kiparski JV, Sarnino N, Vargas D, Atanasova A, Merle R.   +4 more
europepmc   +1 more source

Prevalence of Mastitis in Cows and Raw Milk Microbial Contamination in Selected Districts, Tanzania

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Cow milk produced in Tanzania suffers from poor quality due to bacterial contamination from mastitis udder predisposed by poor livestock husbandry and milk hygienic practices. The prevalence of mastitis was 75.6%, with a milk bacterial contamination rate of 78% and resistance to multiple antimicrobials. To safeguard the dairy industry and public health,
C. Faustine Ndyamukama, G. Msalya, Hezron Emmanuel Nonga   +2 more
wiley   +1 more source

High prevalence of multi-drug resistant H58 Salmonella Typhi and emerging fluoroquinolone resistance among febrile children in Nairobi County, Kenya. [PDF]

BMC Infect Dis
Kavai SM, Mbae C, Mugo M, Njoroge P, Chepchirchir J, Wambui N, Anyona S, Imoli D, Ng'etich R, Kibet E, Odityo G, Mundalo S, Wairimu C, Kariuki M, Njuguna A, Wamucii E, Mbithi W, Owegi D, Muturi P, Kebenei C, Miriti H, Komen N, Kioko C, Kawira M, Kavai J, Osman R, Wakio Z, Ongadi B, Onsare R, Kering K, Kariuki S.   +30 more
europepmc   +1 more source

Isolation, Associated Factors and Antimicrobial Susceptibility Patterns of Salmonella spp. in Human Stool, Eggshell Swab and Feces of Egg‐Laying Hens in Mekelle and Southeast Zones of Tigrai, Ethiopia

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Illustration of Possible Salmonella spp. Contamination Pathways among the Animal‐Food‐Human‐Environment Interface at the Poultry Farm Settings. Source: Author's illustration. ABSTRACT Background Salmonellosis is an important foodborne and zoonotic disease commonly related to the ingestion of poultry products contaminated with Salmonella spp. Although a
Atsebaha Gebrekidan Kahsay, Tsehaye Asmelash, Enquebaher Kassaye   +2 more
wiley   +1 more source

Mechanisms of fluoroquinolone resistance among Escherichia coli isolates from urinary tract infections in Thailand. [PDF]

PLoS One
Tewawong N, Kowaboot S, Lektrakul W, Supcharoengoon U, Watanagul N, Pitaksajjakul P.   +5 more
europepmc   +1 more source

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Brenda Gallegos‐Torres, Edgar Alfonseca‐Silva, Claudia Ledesma‐Carrasco, Itzcoatl Aquino‐Díaz   +3 more
wiley   +1 more source

Rifampicin and isoniazid resistance not promote fluoroquinolone resistance in Mycobacterium smegmatis. [PDF]

PLoS One
Zhou Q, Pu N, Xu G, Liu H, Jia X, Wang X, Xu P.   +6 more
europepmc   +1 more source