Results 251 to 260 of about 5,793,605 (328)

Creb3l1 Overexpression Improves Flexor Tendon Repair in Aged Rats

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Aging impairs flexor tendon repair, with aged tendons showing reduced Col1a1 and Sparc expression and compromised mechanical properties. The transcription factor Creb3l1 binds both gene promoters and drives their expression; its overexpression restores Col1a1 and Sparc levels and improves the gliding function, healing strength, and elastic modulus of ...
Qian Qian Yang   +4 more
wiley   +1 more source

Melioidosis in companion animals: Analysis of 45 Australian cases (24 dogs; 21 cats) from 1997 to 2025 and a brief review of the animal and human literature

open access: yesAustralian Veterinary Journal, Volume 104, Issue 9, Page 563-580, September 2026.
Objective To report 45 cases of melioidosis in dogs and cats from northern Australia and analyse trends in epidemiology, clinical presentation, pathogenesis and response to treatment over a 27‐year period. Design Retrospective and prospective analysis of clinical records.
K Lee   +6 more
wiley   +1 more source

Single‐Cell Immune Profiling Suggests Non‐Classical Monocyte Is Associated Immunodepression in Tuberculosis Treatment Non‐Responders

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 17, September 2026.
ABSTRACT Sputum culture conversion (SCC) at 2 months is an early indicator of tuberculosis (TB) treatment response, yet the associated immune alterations remain incompletely defined. We performed single‐cell RNA sequencing on peripheral blood mononuclear cells from eight TB patients, stratified by 2‐month SCC status.
Yiqun Xiong   +9 more
wiley   +1 more source

Identification of determinants that allow maintenance of high-level fluoroquinolone resistance in <i>Acinetobacter baumannii</i>. [PDF]

open access: yesmBio
Hamami E   +9 more
europepmc   +1 more source

The Synergy Between a Silver‐Ruthenium Antimicrobial and Aminoglycosides Is Based on Severe Macromolecular Damage

open access: yesMolecular Microbiology, Volume 126, Issue 3, Page 267-282, September 2026.
AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun   +9 more
wiley   +1 more source

Relationship Between Fluoroquinolone Resistance and Mutations in the Quinolone Resistance-Determining Region in Corynebacterium macginleyi. [PDF]

open access: yesInvest Ophthalmol Vis Sci
Kato N   +9 more
europepmc   +1 more source

TB drug susceptibility testing in high fluoroquinolone resistance settings. [PDF]

open access: yesIJTLD Open
Saluzzo F   +7 more
europepmc   +1 more source

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