Results 1 to 10 of about 89,788 (98)

Fluorouracil cardiotoxicity. [PDF]

BMJ, 1978
Our of 140 patients treated with intravenous 5-fluorouracil, four developed ischaemic chest pain within 18 hours of either the second or third dose. In three of these patients the pain recurred after subsequent doses. Predose electrocardiograms in two cases were normal.
A, Pottage, S, Holt, S, Ludgate, A O, Langlands   +3 more
  +9 more sources

Fluorouracil Catabolism in the Combination Treatment of Cyclophosphamide, Methotrexate and Fluorouracil [PDF]

Japanese Journal of Cancer Research, 1992
The CMF‐regimen is amongst the most effective chemotherapeutic approaches in the treatment of breast cancer. It is generally accepted that the efficacy of the combination of the three agents used in the regimen, i.e., cyclophosphamide (CY), methotrexate (MTX) and fluorouracil (FUra), is based on interactions between the drugs at the intratumoral level.
Ernst A. De Bruijn, E. E. O. Gheuens, Synke A. M. Van Der Heyden, Robert A. A. Maes   +3 more
openaire   +3 more sources

5-fluorouracil and cardiotoxicity: a review [PDF]

Therapeutic Advances in Medical Oncology, 2018
Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of chemotherapy regimens. 5-FU is in fact the third most commonly used chemotherapeutic agent in the treatment of solid malignancies across the world. As with all chemotherapy, balancing the potential benefits of therapy against the risks of drug-related toxicity is ...
Joerg Herrmann, Ryan Khodadadi, Amir Lerman, Sakti Chakrabarti, Axel Grothey, Ronstan Lobo, Jaskanwal D. Sara, Muneeb Rehman, Jasvinder Kaur   +8 more
openaire   +4 more sources

Fluorouracil: biochemistry and pharmacology.

Journal of Clinical Oncology, 1988
Fluorouracil (5FU) is still considered the most active antineoplastic agent in the treatment of advanced colorectal cancer. The drug needs to be converted to the nucleotide level in order to exert its effect. It can be incorporated into RNA leading to interference with the maturation of nuclear RNA.
H M Pinedo, G F Peters
openaire   +4 more sources

Fluorouracil and angina. [PDF]

BMJ, 1987
C Sponzilli, W Toff
openaire   +2 more sources

The effect of 5-fluorouracil on erythropoiesis [PDF]

Blood, 1991
The effects of a single dose (150 mg/kg) of 5-fluorouracil on mature erythroid and erythropoietic and multipotential in vitro precursor populations in the bone marrow and spleen and circulating biologically (erythroid colony forming unit [CFU-E] assay) and immunologically active (enzyme-linked immunosorbent assay) erythropoietin (Epo) are described ...
openaire   +4 more sources

Unlocking Better Keloid Treatment: Corticosteroid, 5-Fluorouracil, and Hyaluronidase vs. Corticosteroid Alone - A Randomized Comparative Study. [PDF]

Health Sci Rep
Ehsani A, Lotfi F, Firooz A, Ehsani A, Razavi Z, Ansari MS, Nourmohammadpour P, Sima F, Koohian Mohammadabadi M, Rahimnia A.   +9 more
europepmc   +1 more source

5-fluorouracil and beyond. [PDF]

British Journal of Ophthalmology, 1991
Roger A. Hitchings, N. S. C. Rice, Peng T. Khaw, I. Grierson   +3 more
openaire   +3 more sources

Interventional arterial chemotherapy versus sorafenib for advanced hepatocellular carcinoma in China: a health economic evaluation of open-label, randomised, phase 3 study. [PDF]

BMJ Open
Chen QF, Jiang X, Hu Y, Chen S, Lyu N, Zhao M.   +5 more
europepmc   +1 more source

Design, synthesis, molecular docking and molecular dynamics studies of some 3-methoxy flavone derivatives as an anti-breast cancer agent. [PDF]

Discov Oncol
Fegade BS, Chaudhari SY, Likhar RV, Bhole RP, Uttekar PS, Pathare SS, Maitra S, Uti DE, Zaki MEA, Alum EU.   +9 more
europepmc   +1 more source