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Application of chemotherapy combined with immunotherapy in first-line treatment of advanced esophageal cancer: fluorouracil or paclitaxel? – a meta-analysis [PDF]

open access: yesFrontiers in Oncology
IntroductionImmunotherapy combined with chemotherapy is now the first-line standard for metastatic/recurrent esophageal cancer, with rapid immunotherapy advancements significantly improving patient outcomes.
Xiaochen Chen   +4 more
doaj   +2 more sources

Fluorouracil cardiotoxicity. [PDF]

open access: yesBMJ, 1978
Our of 140 patients treated with intravenous 5-fluorouracil, four developed ischaemic chest pain within 18 hours of either the second or third dose. In three of these patients the pain recurred after subsequent doses. Predose electrocardiograms in two cases were normal.
A, Pottage   +3 more
  +9 more sources

A Pilot Study of Peritumor Administration of 5-FU for Preventing Bleeding in Advanced Gastric Cancer

open access: yesThe Korean Journal of Gastroenterology, 2022
Five-FU is a potent chemotherapeutic agent for suppressing endothelial cell growth. The purpose of this study was to investigate the usefulness of local peritumor injection of 5-FU for patients with advanced gastric cancer (AGC) for the prevention of ...
Nam-Hee Kim   +4 more
doaj   +1 more source

Hypertriglyceridemia Induced by Fluorouracil: A Novel Case Report

open access: yesCase Reports in Oncology, 2021
We had previously reported on S-1-induced hypertriglyceridemia. Here, we report fluorouracil-induced hypertriglyceridemia in a patient with capecitabine-induced hypertriglyceridemia and the corresponding therapeutic process.
Yoshitaka Saito   +4 more
doaj   +1 more source

PHYSIOLOGICAL AND BIOCHEMICAL CHANGES FOR 5- FLUOROURACIL DRUG (ANTI-CANCER) IN CANCER PATIENTS [PDF]

open access: yesBasrah Journal of Veterinary Research, 2017
The study was conducted to determine the effect of the 5-Fluorouracil (5-FU) drug is a medication used to treat cancer or the knowledge of 5-FU drug(anticancer) effect might help to attribute these side on physiological and biochemical parameters in ...
Baida R. Ali
doaj   +1 more source

Fluorouracil Catabolism in the Combination Treatment of Cyclophosphamide, Methotrexate and Fluorouracil [PDF]

open access: yesJapanese Journal of Cancer Research, 1992
The CMF‐regimen is amongst the most effective chemotherapeutic approaches in the treatment of breast cancer. It is generally accepted that the efficacy of the combination of the three agents used in the regimen, i.e., cyclophosphamide (CY), methotrexate (MTX) and fluorouracil (FUra), is based on interactions between the drugs at the intratumoral level.
Ernst A. De Bruijn   +3 more
openaire   +3 more sources

MicroRNA-sensitive oncolytic measles virus for chemovirotherapy of pancreatic cancer

open access: yesMolecular Therapy: Oncolytics, 2021
Advanced pancreatic cancer is characterized by few treatment options and poor outcomes. Oncolytic virotherapy and chemotherapy involve complementary pharmacodynamics and could synergize to improve therapeutic efficacy.
Hans Martin Singh   +10 more
doaj   +1 more source

Transient Receptor Potential Cation Channel Subfamily V Member 1 Expression Promotes Chemoresistance in Non-Small-Cell Lung Cancer

open access: yesFrontiers in Oncology, 2022
Approximately 85% of lung cancer cases are non-small-cell lung cancer (NSCLC). Chemoresistance is a leading cause of chemotherapy failure in NSCLC treatment.
Li Li   +6 more
doaj   +1 more source

Modified bi‐weekly cetuximab‐cisplatin and 5‐FU/leucovorin based regimen for effective treatment of recurrent/metastatic head and neck squamous cell carcinoma to reduce chemotherapy exposure of patients

open access: yesCancer Reports, 2022
Background The standard chemotherapy treatment protocol for patients with recurrent/metastatic head and neck squamous cell carcinoma (HNSCC) requires as long as 56 days of hospitalization over six months. Where the 5‐Fluorouracil (5‐FU) pump is available,
Amichay Meirovitz   +7 more
doaj   +1 more source

Chondrosarcoma of Ureter in an Elderly Patient: A Case Report

open access: yesMedicina, 2023
Chondrosarcoma is a rare type of cancer that can affect the upper urinary tract. Because of its rarity, the clinical presentation of chondrosarcoma can be similar to other urinary tract conditions, such as renal colic, hematuria, and urothelial carcinoma.
Szu-Ying Pan   +7 more
doaj   +1 more source

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