Observational study on the efficacy and safety of FOLFOXIRI therapy for locally advanced rectal cancer: The Kanagawa Yokohama Colorectal Cancer Study Group (KYCC)1802. [PDF]
Okamoto H+11 more
europepmc +1 more source
A single‐centre retrospectively analyzed 37 BRPC/LAPC patients receiving neoadjuvant chemotherapy ± chemoradiotherapy. Surgical resection was feasible in 62% of patients, with 38% of patients achieving R0 resections. The median overall survival was 21 months, and disease‐free survival was 12.7 months.
Avtaj Nerwal+5 more
wiley +1 more source
Complete response of advanced esophageal squamous cell carcinoma with first-line chemotherapy combined with immunotherapy: a Case report. [PDF]
Wei Y+8 more
europepmc +1 more source
CDX2 promoter‐controlled oncolytic adenovirus attenuates CDX2‐positive colorectal cancer liver metastasis growth in a mouse model. ABSTRACT Colorectal cancer (CRC) is the second leading cause of cancer death worldwide, and liver metastasis (CRLM) is the most common among its distant metastases.
Naohiko Nakamura+4 more
wiley +1 more source
RETRACTION: Effect of Mitomycin C and 5-Fluorouracil on Wound Healing in Patients Undergoing Glaucoma Surgery: A Meta-Analysis. [PDF]
europepmc +1 more source
Potential effects of adenosine triphosphate and melatonin on oxidative and inflammatory optic nerve damage in rats caused by 5-fluorouracil. [PDF]
Somuncu AM+10 more
europepmc +1 more source
FOLFIRINOX improves the prognosis of patients with pancreatic cancer; however, despite UGT1A1 screening, adverse events, such as severe neutropenia, occur frequently. The diagnostic performance of the neutropenia prediction model showed areas under the curve of 0.754 (sensitivity=0.605, specificity=0.848) and 0.856 (sensitivity=0.800, specificity=0.893)
Gen Kanesada+9 more
wiley +1 more source
GEMPAX, do we have another second-line option after mFOLFIRINOX in pancreatic cancer? [PDF]
Boyle K, Perez KJ.
europepmc +1 more source
Polo‐Like Kinase 1 Expression in Colorectal Cancer: Association With RAS Mutations
PLK1 expression may serve as a biomarker for adjuvant chemotherapy resistance in CRC. This study focused on the relationship between PLK1 expression and RAS mutation, which has been reported to be highly sensitive to PLK1 inhibitors. RAS mutation with high PLK1 expression predicts poorer survival in adjuvant‐treated CRC patients.
Yasushi Tanaka+9 more
wiley +1 more source
The current landscape of gastric cancer and gastroesophageal junction cancer diagnosis and treatment in China: a comprehensive nationwide cohort analysis. [PDF]
Chen Y+10 more
europepmc +1 more source