Results 51 to 60 of about 713,945 (299)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Prompt atmospheric neutrinos and muons: NLO vs LO QCD predictions [PDF]

, 1999
We compare the leading and next-to-leading order QCD predictions for the flux of atmospheric muons and neutrinos from decays of charmed particles.
Gelmini, Graciela, Gondolo, Paolo, Varieschi, Gabriele   +2 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Particle fluxes and gross erosion at limiters in JET low-confinement mode plasmas measured with visible cameras

Nuclear Fusion
Deuterium (D) and beryllium (Be) fluxes are obtained in JET Low-confinement mode (L-mode) plasmas at the outer limiters of the first wall using calibrated visible cameras. They are inferred from the measured radiances using the spectroscopic S/XB method.
E. de la Cal, E.R. Solano, I. Balboa, S. Silburn, E. Pawelec, J. Romazanov, P. Carvalho, J. Karhunen, A. Tookey, S. Bakes, R. Chapman, J. Foster, A. Gonzalez, J. Maddock, J. Matthews, E. Pinto, I. Voldiner, L. Xiang, Y. Zayachuk, JET Contributors   +19 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Simple water vapor sampling for stable isotope analysis using affordable valves and bags [PDF]

Atmospheric Measurement Techniques
Water-stable isotopes are commonly used in hydrological and ecological research. Until now, most measurements of soil or plant water isotopes have been made by taking a sample from the field and extracting its water in the laboratory.
A. Dahlmann, A. Dahlmann, J. D. Marshall, D. Dubbert, M. Hoffmann, M. Dubbert   +5 more
doaj   +1 more source

Fluxes, Gaugings and Gaugino Condensates

, 2006
Based on the correspondence between the N = 1 superstring compactifications with fluxes and the N = 4 gauged supergravities, we study effective N = 1 four-dimensional supergravity potentials arising from fluxes and gaugino condensates in the framework of
Aldazabal G, Angelantonj C, C Kounnas, Cardoso G L, Choi K, Dasgupta K, Derendinger J-P, Gorlich L, J-P Derendinger, Kachru S, Kaloper N, Manousselis P, P Marios Petropoulos, Schon J   +13 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Atmospheric Deposition of Multi-Class Substances into the Ocean: Synthesis of Fluxes, Seasonal Spatial Patterns and Ecological Risks

Journal of Marine Science and Engineering
Atmospheric deposition is increasingly recognized as a significant pathway transporting diverse substances from land to the ocean. However, significant uncertainties persist regarding the magnitude, spatial variability, and ecological implications of ...
Qinghao Lin, Xianliang Yi, Junyi Wang, Yiwen Zhang, Jingjing Zhan   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source