Results 71 to 80 of about 713,945 (299)

A model measurements comparison of atmospheric forcing and surface fluxes of the Baltic Sea [PDF]

open access: yes, 2006
Observed basic meteorological quantities, heat and radiation fluxes from three different measurement stations in the Baltic Sea are compared with model data of the coupled sea-ice-ocean model BSIOM in order to evaluate the atmospheric forcing ...
Lehmann, Andreas, Rudolph, Claudia
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Assessment of Fluxes and Ecological and Health Risks of Toxic Trace Elements in Atmospheric Deposition from the Baicheng-Songyuan Area, Jilin Province, Northeast China

open access: yesAtmosphere
A total of 56 atmospheric deposition samples were collected on a yearly basis from the Baicheng-Songyuan areas, Jilin Province, Northeast China. Each sample was subdivided into wet (soluble) and dry (insoluble) fractions, and the concentrations of toxic ...
Yinghong Liu, Wen Gao, Sheli Chai
doaj   +1 more source

METHANE EMISSIONS FROM THERMOKARST LAKES IN THE SOUTHERN TUNDRA OF WESTERN SIBERIA

open access: yesGeography, Environment, Sustainability, 2018
Lakes are an important natural source of methane – significant greenhouse gas of the modern atmosphere. Monitoring of methane emission from lakes ofnorthern territoriesis needed to update the available estimates of CH4 emission intensity into the ...
Vladimir S. Kazantsev   +2 more
doaj   +1 more source

Spectral statistics of disordered metals in the presence of several Aharonov-Bohm fluxes

open access: yes, 1997
The form factor for spectral correlations in a diffusive metal is calculated in the presence of several Aharonov-Bohm fluxes. When the fluxes $\phi$ are equal, the correlations are universal functions of $n g^2 \phi$ where $g$ is the dimensionless ...
%L.P. Lévy   +16 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

D-Terms from Generalized NS-NS Fluxes in Type II

open access: yes, 2007
Orientifolds of type II string theory admit a certain set of generalized NS-NS fluxes, including not only the three-form field strength H, but also metric and non-geometric fluxes, which are related to H by T-duality.
A. Achucarro   +23 more
core   +3 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A New Mechanism of Kahler Moduli Stabilization in Type IIB Theory [PDF]

open access: yes, 2006
We study the scalar potential in supersymmetric (orientifolded) Calabi Yau compactifications of Type IIB theory. We present a new mechanism to stabilize all closed string moduli at leading order in \alpha^{'} by introducing consistently fluxes.
del Moral, Maria Pilar Garcia
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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