Results 61 to 70 of about 713,945 (299)
M5-brane geometries, T-duality and fluxes
, 2003 We describe a duality relation between configurations of M5-branes in M-theory and type IIB theory on Taub-NUT geometries with NSNS and RR 3-form field strength fluxes.
A. Sen +22 more
core +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Frontiers in Marine Science, 2020 Coastal ecosystems are subject to multiple processes that drive pH change over time. Therefore, efforts to understand the variability in the coastal carbonate system are crucial to assess the marine system vulnerability to acidification.
Lidia Urbini +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Simulation of Atmospheric Muon and Neutrino Fluxes with CORSIKA
, 2003 The fluxes of atmospheric muons and neutrinos are calculated by a three dimensional Monte Carlo simulation with the air shower code CORSIKA using the hadronic interaction models DPMJET, VENUS, GHEISHA, and UrQMD.
Alexandru Bercuci +64 more
core +1 more source
A Search for Radio Emission at the Bottom of the Main Sequence and Beyond [PDF]
, 1999 We have used the VLA to conduct a deep search for 3.6 cm radio emission from nearby very low mass stars and brown dwarfs. The Gudel-Benz relation is used to predict radio luminosities for some very low mass stars and candidate brown dwarfs with measured ...
Anita Krishnamurthi +3 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Gayana, 2006 Vertical fluxes of particles have been estimated during the last decade in coastal and oceanic systems off central-southern Chile. Free-drifting, cylindrical sediment traps have been deployed below the mixing layer from coastal areas, while automatic ...
H E González +8 more
doaj
A Surface Ocean CO2 Reference Network, SOCONET and Associated Marine Boundary Layer CO2 Measurements
Frontiers in Marine Science, 2019 The Surface Ocean CO2 NETwork (SOCONET) and atmospheric Marine Boundary Layer (MBL) CO2 measurements from ships and buoys focus on the operational aspects of measurements of CO2 in both the ocean surface and atmospheric MBLs.
Rik Wanninkhof +30 more
doaj +1 more source