Results 91 to 100 of about 14,055 (218)

Advances in Foot-and-Mouth Disease Virus Proteins Regulating Host Innate Immunity

Frontiers in Microbiology, 2020
Foot-and-mouth disease (FMD) is a highly contagious disease that affects cloven-hoofed animals such as pigs, cattle, and sheep. The disease is caused by the foot-and-mouth disease virus (FMDV) which has a non-enveloped virion with icosahedral symmetry ...
Jiangling Peng, Jiamin Yi, Wenping Yang, Jingjing Ren, Yuan Wen, Haixue Zheng, Dan Li   +6 more
doaj   +1 more source

Cattle remain immunocompetent during the acute phase of foot-and-mouth disease virus infection [PDF]

, 2011
Infection of cattle with foot-and-mouth disease virus (FMDV) results in the development of long-term protective antibody responses. In contrast, inactivated antigen vaccines fail to induce long-term protective immunity.
Miriam A Windsor, B Veronica Carr, Bartomiej Bankowski, Debi Gibson, Elizabeth Reid, Pip Hamblin, Simon Gubbins, Nicholas Juleff, Bryan Charleston   +8 more
core   +1 more source

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li, Junhua Deng, Zenglin Wang, Yunjing Zhang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li, Linzhu Ren   +8 more
wiley   +1 more source

Insights into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate. [PDF]

, 2010
Accepted ...
Allaire, Belsham, Belsham, Bergmann, Birtley, Birtley, Bjorndahl, Blom, Brunger, Brünger, Carrillo, Cordingley, Cordingley, Curry, Curry, Delano, Ellard, Frigerio, Fujinaga, Graham J. Belsham, Grubman, Grubman, Hedstrom, Hodis, Huber, Jaulent, Jewell, Jingjie Yang, Jones, Laskowski, Lee, Li, Long, Matthews, Matthews, McCoy, Mosimann, Nayak, Núria Roqué-Rosell, Pallai, Patricia A. Zunszain, Perona, Perona, Perona, Phan, Prasad, Reid, Robin J. Leatherbarrow, Schechter, Seipelt, Skern, Stephen Curry, Stephen R. Knox, Sutmoller, Sweeney, Trevor R. Sweeney, Tsunogae, Xue, Yin, Yin   +59 more
core   +1 more source

Phorbol Myristate Acetate Inhibits Senecavirus A Replication by Activating IKBKE–Mediated IFN Pathway and NF‐κB Signal

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease indistinguishable from foot‐and‐mouth disease virus (FMDV). So far, there are no commercial vaccines and effective therapeutic drugs against SVA infection in China. Here, a library of 112 compounds were screened, and we found that phorbol myristate acetate plays an antagonistic ...
Junfang Yan, Yanni Gao, Chengyi Guo, Yubei Dong, Ping Jiang, Juan Bai, Linzhu Ren   +6 more
wiley   +1 more source

Foot-and-mouth disease virus genome replication is unaffected by inhibition of type III phosphatidylinositol-4-kinases [PDF]

, 2016
Foot-and-mouth disease virus (FMDV) causes economically-damaging infections of cloven-hooved animals, with outbreaks resulting in large financial losses to the agricultural industry.
Belsham, Devaney, Eleni-Anna Loundras, Kirchweger, Mark Harris, Martínez-Salas, Morgan R. Herod, Nicola J. Stonehouse, Thompson, Tsukiyama-Kohara   +9 more
core   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source

Prevalence and Serotype Distribution of Foot and Mouth Disease (FMD) Virus in Asian Countries: A Systematic Review and Meta‐Analysis

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Background Foot and mouth disease (FMD) is a highly contagious transboundary List A infectious disease of domesticated and wild cloven‐hoofed animals, causing considerable economic impact through production losses and trade bans on livestock. Objective This study aimed to determine the pooled prevalence of FMD and the distribution of FMD virus ...
Md Jisan Ahmed, Md Imran Hossain, Md Arifur Rahman, Md Ismile Hossain Bhuiyan, Prajwal Bhandari, Kazi Estieque Alam, Ritu Chalise, Israt Jahan Kaderi, Md Afiqul Islam Rahi, Tashmiah Tarin, Md Jahangir Alam, Ridwan Olamilekan Adesola, Delower Hossain, Mahmoud Elhaig   +13 more
wiley   +1 more source

Detection of foot-and-mouth disease virus rna by reverse transcription loop-mediated isothermal amplification [PDF]

, 2011
A reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay was developed for foot-and-mouth disease virus (FMDV) RNA. The amplification was able to finish in 45 min under isothermal condition at 64°C by employing a set of four primers
Hao-tai Chen, Jie Zhang, Yong-sheng Liu, Xiang-tao Liu   +3 more
core   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source