Virology Journal, 2011 Background Foot-and-mouth disease virus (FMDV) causes an economically important and highly contagious disease of cloven-hoofed animals. RNAi triggered by small RNA molecules, including siRNAs and miRNAs, offers a new approach for controlling viral ...
Cai Xuepeng +8 more
doaj +1 more source
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
, 2018 Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna +5 more
core +1 more source
The structure of a protein primer-polymerase complex in the initiation of genome replication [PDF]
, 2015 Picornavirus RNA replication is initiated by the covalent attachment of a UMP molecule to the hydroxyl group of a tyrosine in the terminal protein VPg. This reaction is carried out by the viral RNA-dependent RNA polymerase (3D). Here, we report the X-ray
Agudo, Rubén +6 more
core +1 more source
Laboratory capacity for diagnosis of foot-and-mouth disease in Eastern Africa: implications for the progressive control pathway [PDF]
, 2013 Background Accurate diagnosis is pertinent to any disease control programme. If Eastern Africa is to work towards control of foot-and-mouth disease (FMD) using the Progressive Control Pathway for FMD (PCP-FMD) as a tool, then the capacity of national ...
Ayebazibwe, Chrisostom +6 more
core +4 more sources
Employing transposon mutagenesis to investigate foot-and-mouth disease virus replication [PDF]
, 2015 Probing the molecular interactions within the foot-and-mouth disease virus (FMDV) RNA replication complex has been restricted in part to the lack of suitable reagents.
Belsham +17 more
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A universal protocol to generate consensus level genome sequences for foot-and-mouth disease virus and other positive-sense polyadenylated RNA viruses using the Illumina MiSeq [PDF]
, 2014 BACKGROUND: Next-Generation Sequencing (NGS) is revolutionizing molecular epidemiology by providing new approaches to undertake whole genome sequencing (WGS) in diagnostic settings for a variety of human and veterinary pathogens.
Bachanek-Bankowska, K +8 more
core +1 more source
PLoS PathogensThe interaction between foot-and-mouth disease virus (FMDV) and the host is extremely important for virus infection, but there are few researches on it, which is not conducive to vaccine development and FMD control.
Gaochuang Peng +11 more
doaj +1 more source
Virulence beneath the fleece; a tale of foot-and-mouth disease virus pathogenesis in sheep.
PLoS ONE, 2019 Foot-and-mouth disease virus (FMDV) is capable of infecting all cloven-hoofed domestic livestock species, including cattle, pigs, goats, and sheep. However, in contrast to cattle and pigs, the pathogenesis of FMDV in small ruminants has been incompletely
Carolina Stenfeldt +5 more
doaj +1 more source
Design, Synthesis and Analysis of FMDV 3C-Protease Inhibitors
, 2008 Foot-and-mouth disease virus (FMDV) causes a highly infectious disease of cloven-hoofed livestock with economically devastating consequences. The political and technical problems associated with the use of FMDV vaccines make drug-based disease control an attractive alternative.
Roqué-Rosell, Núria +1 more
openaire +3 more sources
Development of a recombinant foot -and-mouth disease vaccine [PDF]
, 2014 Foot-and-mouth disease (FMD) is important disease of cloven-foot animals including cows and swine. Although annual vaccination against the FMD is mandated in regions of South Kazakhstan, outbreaks of the disease are registered every year.
Kalieva, M. Zh. +4 more
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