Results 101 to 110 of about 10,541 (227)

Detection of Foot-and-Mouth Disease Virus in Swine Meat Juice

Pathogens, 2020
Foot-and-mouth disease virus (FMDV) is a highly contagious agent that impacts livestock industries worldwide, leading to significant financial loss. Its impact can be avoided or minimized if the virus is detected early. FMDV detection relies on vesicular
Sean Yeo, Ming Yang, Martin Nyachoti, Rolf Rauh, Johnny D. Callahan, Charles Nfon   +5 more
doaj   +1 more source

Epidemiology of Foot‐and‐Mouth Disease in Goats in Uganda: A Risk‐Based Approach

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Foot‐and‐mouth disease (FMD) is a highly contagious viral disease with major economic implications for the livestock sector in Uganda. Although cattle are the primary focus of FMD control in Uganda, small ruminants are also susceptible and interact with cattle in mixed species grazing systems.
Benedicto Byamukama, Asfor Amin, Frank Norbert Mwiine, Susan D. Kerfua, Abel Bulamu Ekiri, Fedor Korennoy   +5 more
wiley   +1 more source

Characterisation of FMDV empty capsids. [PDF]

, 2016
(A) 12% PAGE for fractions (FR5 and FR6) collected from a sucrose gradient for purification of stabilised FMDV EC (A22ecKGA). The major bands represent VP1-3. VP1 runs slightly slower than VP2 and VP3, which co-migrate as a single band.
Gareth Shimmon (3142221), Stephen Berryman (3142212), Donald P. King (116717), Britta A. Wood (2918993), Alison Burman (395426), Terry Jackson (363618), Toby Tuthill (3142215), Alison Morris (371631), Valerie Mioulet (3142218), Emiliana Brocchi (845655), Santina Grazioli (845653)   +10 more
core   +1 more source

Engineered PCV2 VLPs for Antigen Delivery: A Platform for Next‐Generation Veterinary Vaccines

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The capsid (Cap) protein of porcine circovirus type 2 (PCV2) self‐assembles into virus‐like particles (VLPs) that form stable, noninfectious nanoparticles with T = 1 icosahedral symmetry. Mimicking native virion architecture, these VLPs display antigens in a highly ordered array, conferring strong immunogenicity for both humoral and cellular responses.
Peiyang Ding, Yating Liu, Chenyu Wang, Aiping Wang, Linzhu Ren   +4 more
wiley   +1 more source

Replication of FMDV C-S8c1 in CD172⁺- MoDC. [PDF]

, 2013
CD172+ cells were purified from swine PBMCs (see Material and Methods) and put in culture with rpGM-CSF and rpIL-4. The cells were infected either at D0 (just after purification) or D5 (5 days in culture with rpGM-CSF and rpIL-14) with FMDV C-S8c1 at moi
Noemí Sevilla (317977), Ana de Avila (372677), Fayna Díaz-San Segundo (372675), Teresa Rodríguez-Calvo (317975)   +3 more
core   +1 more source

Adaptive Evolution of Serotype O Foot‐and‐Mouth Disease Virus Under Vaccine Pressure: Combined VP1 T142/Q153 Mutations Drive Antigenic Alteration and Immune Evasion

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Foot‐and‐mouth disease virus (FMDV) escapes host immune surveillance via adaptive evolution driven by vaccine‐mediated selective pressure, leading to persistent breakthrough infections in immunized animals. In this study, the dominant neutralizing epitope VP1 G–H loop (141–160 aa) was analyzed among 46 serotype O FMDV strains belonging to Southeast ...
Nan Cao, Yamei Li, Xinghua Chen, Qiongqiong Zhao, Jinyan Zhang, Xianfei Shang, Junling Hou, Jinming Zhang, Bo Yin, Jinyan Wu, Xiangmin Li, Ping Qian, Nan-hua Chen   +12 more
wiley   +1 more source

Efficacy of Recombinant Genetic Diagnostic Tools for Foot-and-Mouth Disease Virus (FMDV)

Journal of Scientific Research in Science
The Foot and Mouth Disease Virus (FMDV) is one of the most fearful animal viruses infecting all cloven-footed species and causing significant economic losses in the global livestock industry.
Mai M. Abd El-Rahman, Rokaya H. Shalaby, Alaa A. E .El-Kholy, Noura R. Mohamed, Shereen H. B. Elwakeel   +4 more
doaj   +1 more source

Foot-and-mouth disease virus (FMDV) with a stable FLAG epitope in the VP1 G-H loop as a new tool for studying FMDV pathogenesis

Virology, 2013
Foot-and-mouth disease virus (FMDV) VP1 G-H loop contains the major antigenic site. By replacing the sequence upstream of the RGD motif with a FLAG epitope, a marker virus for pathogenesis studies was generated. In cell culture, the recombinant virus containing FLAG (A24-FLAG) exhibited similar plaque phenotypes and growth kinetics to parental virus ...
Lawrence, P, Pacheco, J, Uddowla, S, Hollister, J, Kotecha, A, Fry, E, Rieder, E   +6 more
openaire   +3 more sources

Spatial Patterns and Epidemiological Drivers of Foot‐and‐Mouth Disease Outbreaks in Uganda

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Foot‐and‐mouth disease (FMD) places a heavy economic burden on farmers and animal health authorities due to its clinical effects, the high cost associated with its prevention and control, and trade restrictions on livestock and livestock products in countries without FMD‐free recognition like Uganda.
Lina González Gordon, Dennis Muhanguzi, Adrian Muwonge, Sylvester Ochwo, Noelina Nantima, Rose Ademun, Lisa Boden, Norbert Frank Mwiine, Barend Mark de C. Bronsvoort, Thibaud Porphyre, Fedor Korennoy   +10 more
wiley   +1 more source

Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication

PLOS ONE, 2015
Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the dimer interface is essential for virus replication.
González Magaldi, Mónica, Vázquez Calvo, Ángela, Torre, Beatriz G. de la, Valle, Javier, Andreu Martínez, David, Sobrino, Francisco   +5 more
openaire   +6 more sources