Results 111 to 120 of about 13,911 (208)

A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways.

PLoS Pathogens
The interaction between foot-and-mouth disease virus (FMDV) and the host is extremely important for virus infection, but there are few researches on it, which is not conducive to vaccine development and FMD control.
Gaochuang Peng, Tianran Liu, Xiaolan Qi, Yuzhe Wang, Jingjing Ren, Jiangling Peng, Xuguang Du, Siyu Hu, Sen Wu, Yaofeng Zhao, Dan Li, Haixue Zheng   +11 more
doaj   +1 more source

The Role of the Early Secretory Pathway in Foot-and-Mouth Disease Virus Replication

, 2011
Foot-and-Mouth Disease Virus (FMDV) induces rearrangements of host-cell membranes to generate vesicles that are believed to provide platforms for formation of the viral replication complex. The cellular origin of these vesicles and the properties that
Midgley, Rebecca Julie, Midgley, Rebecca Julie   +1 more
core   +1 more source

Detection of foot-and-mouth disease virus rna by reverse transcription loop-mediated isothermal amplification [PDF]

, 2011
A reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay was developed for foot-and-mouth disease virus (FMDV) RNA. The amplification was able to finish in 45 min under isothermal condition at 64°C by employing a set of four primers
Hao-tai Chen, Jie Zhang, Yong-sheng Liu, Xiang-tao Liu   +3 more
core   +1 more source

Inactivation of Foot-and-Mouth Disease Virus in Milk Products [PDF]

, 2012
Foot-and-mouth disease (FMD) is a viral infection that mainly occurs in cloven-hooved animals including commercially important species such as cattle, sheep, goats, swine and (water) buffalo.
Roth, James, Roth, James, Spickler, Anna
core   +2 more sources

Virulence beneath the fleece; a tale of foot-and-mouth disease virus pathogenesis in sheep.

PLoS ONE, 2019
Foot-and-mouth disease virus (FMDV) is capable of infecting all cloven-hoofed domestic livestock species, including cattle, pigs, goats, and sheep. However, in contrast to cattle and pigs, the pathogenesis of FMDV in small ruminants has been incompletely
Carolina Stenfeldt, Juan M Pacheco, Nagendrakumar B Singanallur, Wilna Vosloo, Luis L Rodriguez, Jonathan Arzt   +5 more
doaj   +1 more source

Design, Synthesis and Analysis of FMDV 3C-Protease Inhibitors

, 2008
Foot-and-mouth disease virus (FMDV) causes a highly infectious disease of cloven-hoofed livestock with economically devastating consequences. The political and technical problems associated with the use of FMDV vaccines make drug-based disease control an attractive alternative.
Roqué-Rosell, Núria, Roqué-Rosell, Núria   +1 more
openaire   +3 more sources

Interferon-stimulated gene MCL1 inhibits foot-and-mouth disease virus replication by modulating mitochondrial dynamics and autophagy

Journal of Virology
Interferons (IFNs) and the IFN-stimulated genes (ISGs) that they induce are effective in reducing the replication of foot and mouth disease virus (FMDV).
Aishwarya Mogulothu, Danielle Hickman, Sarah Attreed, Paul Azzinaro, Monica Rodriguez-Calzada, Meike Dittmann, Teresa de los Santos, Steven Szczepanek, Gisselle N. Medina   +8 more
doaj   +1 more source

Universal amplification and sequencing of foot-and-mouth disease virus complete genomes using nanopore technology

BMC Genomics
Background Foot-and-mouth disease virus (FMDV) is capable of causing explosive outbreaks among domestic and wild cloven-hoofed animals. Genomic characterisation of FMDV is a crucial component of disease control enabling accurate tracing of disease ...
Andrew E. Shaw, Kebaneilwe Lebani, Lina González Gordon, Ugonna E. Ihearahu, Jemma Wadsworth, Hayley M. Hicks, Noemi Polo, Graham Freimanis, Dennis Muhanguzi, Chandana Tennakoon, Richard J. Orton, Nick J. Knowles, Antonello Di Nardo, Ryan A. Waters, Barend MdeC Bronsvoort, Donald P. King   +15 more
doaj   +1 more source

THE ROLE OF RISK ASSESSMENT IN MANAGING RISK [PDF]

Risk and Uncertainty,
Ahmad, A., Ayanwale, L., Beyene, G., Habtemariam, Tsegaye, Nganwa, D., Robnett, V., Tameru, B.   +6 more
core   +1 more source

Molecular epidemiology of foot and mouth disease virus (FMDV) in Chad [PDF]

, 2017
Foot and mouth disease (FMD) is a highly contagious viral disease affecting domestic and wild artiodactyl animals. Its causative agent is foot-and–mouth disease virus (FMDV: Aphtovirus, Picornaviridae).
Abdel-Aziz, Arada Izzedine, Bakkali Kassimi, Labib, Blaise-Boisseau, Sandra, Gorna, Kamila, Laloy, Eve, Lancelot, Renaud, Relmy, Anthony, Romey, Aurore, Zientara, Stéphan   +8 more
core