Results 61 to 70 of about 7,938 (206)

Development of Foot-and-Mouth Disease Virus-Neutralizing Monoclonal Antibodies Derived From Plasmablasts of Infected Cattle and Their Germline Gene Usage

Frontiers in Immunology, 2019
Cattle are susceptible to foot-and-mouth disease virus (FMDV), and neutralizing antibodies are critical for protection against FMDV infection in this species.
Kun Li, Sheng Wang, Yimei Cao, Huifang Bao, Pinghua Li, Pu Sun, Xingwen Bai, Yuanfang Fu, Xueqing Ma, Jing Zhang, Dong Li, Yingli Chen, Xuerong Liu, Fanglan An, Faju Wu, Zengjun Lu, Zaixin Liu   +16 more
doaj   +1 more source

Age-dependent immune response in pigs against foot-and-mouth disease virus in vitro

Journal of Animal Science and Technology, 2021
Foot-and-mouth disease, one of the most contagious diseases in cloven-hoofed animals, causes significant economic losses. The pathogenesis of foot-and-mouth disease virus (FMDV) infection is known to differ with ...
Jae-Hee Roh, Ngoc Anh Bui, Hu Suk Lee, Vuong Nghia Bui, Duy Tung Dao, Thanh Thi Vu, Thuy Thi Hoang, Kyoung-Min So, Seung-Won Yi, Eunju Kim, Tai-Young Hur, Sang-Ik Oh   +11 more
doaj   +1 more source

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li, Junhua Deng, Zenglin Wang, Yunjing Zhang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li, Linzhu Ren   +8 more
wiley   +1 more source

Diagnostic Overview of Foot-And-Mouth Disease Viruse (FMDV)

South Asian Research Journal of Agriculture and Fisheries, 2023
Foot-and-mouth disease (FMD) is one of the highly contagious diseases of domestic animals. Sensitive, specific, and quick detection of FMD virus antigens and antibodies is an essential corner stone diagnostic tool at each tier of control strategy. Continued development of molecular and genetic technologies combined with novel analytical techniques will ...
Ephrem Shimelis, Shimels Tesfaye, Fanos Tadesse   +2 more
openaire   +1 more source

Efficacy of an adenovirus-vectored foot-and-mouth disease virus serotype A subunit vaccine in cattle using a direct contact transmission model

BMC Veterinary Research, 2018
Background A direct contact transmission challenge model was used to simulate natural foot-and-mouth disease virus (FMDV) spread from FMDV A24/Cruzeiro/BRA/55 infected ‘seeder’ steers to naïve or vaccinated steers previously immunized with a replication ...
John G. Neilan, Christopher Schutta, José Barrera, Melia Pisano, Laszlo Zsak, Ethan Hartwig, Max V. Rasmussen, Barbara J. Kamicker, Damodar Ettyreddy, Douglas E. Brough, Bryan T. Butman, David A. Brake   +11 more
doaj   +1 more source

Phorbol Myristate Acetate Inhibits Senecavirus A Replication by Activating IKBKE–Mediated IFN Pathway and NF‐κB Signal

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging picornavirus causing vesicular disease indistinguishable from foot‐and‐mouth disease virus (FMDV). So far, there are no commercial vaccines and effective therapeutic drugs against SVA infection in China. Here, a library of 112 compounds were screened, and we found that phorbol myristate acetate plays an antagonistic ...
Junfang Yan, Yanni Gao, Chengyi Guo, Yubei Dong, Ping Jiang, Juan Bai, Linzhu Ren   +6 more
wiley   +1 more source

Foot-and-mouth disease virus VP1 promotes viral replication by regulating the expression of chemokines and GBP1

Frontiers in Veterinary Science, 2022
Foot-and-mouth disease virus (FMDV) is an acute, highly contagious, and economically destructive pathogen of vesicular disease that affects domestic and wild cloven-hoofed animals. The FMDV VP1 protein is an important part of the nucleocapsid and plays a
Li Yang, Li Yang, Li Yang, Hong Chen, Hong Chen, Hong Chen, Liqing Liu, Liqing Liu, Liqing Liu, Jingjing Song, Jingjing Song, Jingjing Song, Tian Feng, Tian Feng, Tian Feng, Yihan Li, Yihan Li, Yihan Li, Chao Shen, Lingbao Kong, Lingbao Kong, Lingbao Kong, Xiu Xin, Xiu Xin, Xiu Xin   +24 more
doaj   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source

Proof of Proficiency of Decentralized Foot-and-Mouth Disease Virus Diagnostics in Germany

Viruses, 2022
A proficiency test was performed to verify that the regional veterinary laboratories in Germany can provide reliable foot-and-mouth disease virus (FMDV) diagnostics.
Hanna Keck, Bernd Hoffmann, Michael Eschbaumer   +2 more
doaj   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source