Results 51 to 60 of about 98,246 (140)
Advanced Functional Materials, Volume 36, Issue 73, 10 September 2026.Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik +8 more
wiley +1 more source
Asian Journal of Organic Chemistry, Volume 15, Issue 7, July 2026.The phosphoroorganic modification of Smac‐mimetics (SMs) drives selectivity for cIAP1‐ over XIAP‐BIR3. The divalent SM 6 partially dimerizes cIAP1, whereas it prefers intramolecular binding in XIAP. In XIAP the phosphoroorganic moiety of the monovalent SM 7 functions as an IBM, thus inhibiting both BIR2 and BIR3. Created in BioRender.
Elisa Fagnani +7 more
wiley +1 more source
Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy
Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.Abstract INTRODUCTION A subset of Alzheimer's disease (AD) patients exhibits a procoagulant state that remains undiagnosed despite available treatments. We developed positron emission tomography (PET) strategies to in vivo detect cerebral microthrombi in TgCRND8 mice. METHODS PET was performed with a fibrin‐binding probe (FBP) in TgCRND8 and wild‐type
Carlos Ceron +22 more
wiley +1 more source
Peptide-Based Hydrogels and Nanogels for Delivery of Doxorubicin
International Journal of Nanomedicine, 2021 Enrico Gallo,1 Carlo Diaferia,2 Elisabetta Rosa,2 Giovanni Smaldone,1 Giancarlo Morelli,2 Antonella Accardo2 1IRCCS SDN, Naples, 80143, Italy; 2Department of Pharmacy and Research Centre on Bioactive Peptides (CIRPeB), University of Naples &ldquo ...
Gallo E +5 more
doaj
, 2015 Diphenylalanine (FF) and chemically modified FF-peptides are very common peptides with many potential applications, both biological and technological, due to a large number of different nanostructures which they attain. Experimental observations indicate
Τζέλη, Δέσποινα
core
Histidine Ethylation by Histidine Methyltransferases SETD3 and METTL9
ChemBioChem, Volume 27, Issue 12, 26 June 2026.Enzyme assays and computational analyses reveal that human histidine methyltransferases SETD3 and METTL9 have a capacity to catalyze histidine ethylation in the presence of synthetic or in situ produced S‐adenosylethionine (AdoEth) and Se‐adenosylselenoethionine (AdoSeEth) cosubstrates.
Jordi C. J. Hintzen +14 more
wiley +1 more source
Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.Cin‐FF's biocompatibility is concentration and formulation (gel or solution) dependent, showing varied effects on bacterial strains and cell lines. ABSTRACT This study evaluates cinnamoyl‐diphenylalanine dipeptide (Cin‐FF), a newly introduced gelator, for its antimicrobial efficacy, biocompatibility, and potential anticancer properties in solution and ...
Efstratios D. Sitsanidis +7 more
wiley +1 more source
Perovskite Film Passivated by Fmoc-FF-OH and Its Photovoltaic Performance
Journal of Inorganic Materials, 2023 Jian SONG +5 more
openaire +2 more sources
Substrate selectivity of human histidine methyltransferase METTL9
Protein Science, Volume 35, Issue 5, May 2026.Abstract Methylation of histidine residues in zinc transporters by histidine methyltransferase METTL9 plays an important role in modulating their metal‐binding properties. Here, we report synthetic, enzymatic, and computational studies on human METTL9‐catalyzed Nπ‐methylation of His375 in zinc transporter SLC39A5‐derived peptides in which the histidine
Sadaf Ahmad +7 more
wiley +1 more source
Designing unconventional Fmoc-peptide-based biomaterials: structure and related properties
, 2014 We have recently employed L-amino acids in the lipase-catalyzed biofabrication of a class of self-assembling Fmoc-peptides that form 3-dimensional nanofiber scaffolds. Here we report that using D-amino acids, the homochiral self-assembling peptide Fmoc-D-
DENTINI, Mariella +10 more
core +1 more source