Results 31 to 40 of about 98,246 (140)

Self-assembled Structures Formed by Fmoc modified aliphatic amino acids [PDF]

, 2021
We report the self-assembled structures formed by Fmoc modified aliphatic uncharged single amino acids. The self-assembling properties of (((9H-fluoren-9-yl)methoxy)carbonyl)-L-alanine (Fmoc-Ala-OH), (((9H-fluoren-9-yl)methoxy)carbonyl)-L-leucine (Fmoc ...
Bharti , Koshti, Hanuman, Narode, Soumick , Naskar, Nidhi, Gour, Vivekshinh, Kshtriya   +4 more
core   +1 more source

Ultrasound-Actuated Gene Editing in Human Kidney Organoids. [PDF]

Adv Sci (Weinh)
Peptide‐stabilized nanoemulsions enable spatially controlled, ultrasound‐triggered delivery of gene‐editing proteins deep within human kidney organoid tissues. Focused acoustic pulses drive droplet vaporization, propelling cargo into target renal cells while preserving native tissue microarchitecture. This non‐viral platform improves both the depth and
Miller MA, Vo N, Utkarsh, Sokirniy I, Pritchard J, Freedman BS, Medina SH.   +6 more
europepmc   +2 more sources

Controlled Morphological Changes in Self-Assembled Structures Formed by Fmoc Variants of Threonine and Serine [PDF]

, 2021
We report for the very first time the self-assembly of Fmoc variant 2-(9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid of threonine (Fmoc-Thr(tbu)-OH) and of serine (Fmoc-Ser(tbu)-OH.
Nidhi, Gour, Vivekshinh, Kshtriya, Bharti, Koshti   +2 more
core   +1 more source

Integrin receptor-binding nanofibrous peptide hydrogel for combined mesenchymal stem cell therapy and nitric oxide delivery in renal ischemia/reperfusion injury

Stem Cell Research & Therapy, 2022
Background Mesenchymal-based therapy has been utilized as a practical approach in the treatment of renal ischemia/reperfusion (I/R) injury. However, low cell retention and survival in the ischemic site have remained challenging issues. To bridge this gap,
Haniyeh Najafi, Samira Sadat Abolmaali, Reza Heidari, Hadi Valizadeh, Ali Mohammad Tamaddon, Negar Azarpira   +5 more
doaj   +1 more source

Expanding the Functional Scope of the Fmoc‐Diphenylalanine Hydrogelator by Introducing a Rigidifying and Chemically Active Urea Backbone Modification

Advanced Science, 2019
Peptidomimetic low‐molecular‐weight hydrogelators, a class of peptide‐like molecules with various backbone amide modifications, typically give rise to hydrogels of diverse properties and increased stability compared to peptide hydrogelators.
Vasantha Basavalingappa, Tom Guterman, Yiming Tang, Sivan Nir, Jiangtao Lei, Priyadarshi Chakraborty, Lee Schnaider, Meital Reches, Guanghong Wei, Ehud Gazit   +9 more
doaj   +1 more source

Fmoc-2-Mercaptobenzothiazole (MBT), for the Introduction of the Fmoc Moiety Free of Side-Reactions [PDF]

, 2013
A double side-reaction, consisting in the formation of Fmoc--Ala-OH and Fmoc--Ala-AA-OH, during the preparation of Fmoc protected amino acids (Fmoc-AA-OH) with Fmoc-OSu is discussed.
Isidro Llobet, Albert, Álvarez Domingo, Mercedes, Albericio Palomera, Fernando, Ewenson, Ariel, Just Baringo, Xavier   +4 more
core   +7 more sources

Fmoc solid-phase synthesis of RF9 optimization with mass spectrometry verification

Current Issues in Pharmacy and Medical Sciences, 2022
The RF9 compound, which is an antagonist of the FF neuropeptide receptors is used as a therapeutic substance to improve the effectiveness of opioids in the chronic treatment of pain.
Orocz Marta, Hartman Kinga, Smoluch Marek, Silberring Jerzy, Mielczarek Przemyslaw   +4 more
doaj   +1 more source

A practical synthesis of the 13C/15N-labelled tripeptide N-formyl-Met-Leu-Phe, useful as a reference in solid-state NMR spectroscopy [PDF]

, 2008
A mild synthetic method for N-formyl-Met-Leu-Phe-OH (1) is described. After Fmoc solid phase peptide synthesis, on-bead formylation and HPLC purification, more than 30 mg of the fully 13C/15N-labelled tripeptide 1 could be isolated in a typical batch ...
Suhartono, Marcel, Michael W. Göbel, Göbel, Michael, Jakob J. Lopez, Clemens Glaubitz, Dürner, Gerd, Sven T. Breitung, Lopez, Jakob J., Marcel Suhartono, Breitung, Sven Thomas, Gerd Dürner, Glaubitz, Clemens   +11 more
core   +1 more source

Effect of glycine substitution on fmoc-diphenylalanine self-assembly and gelation properties

, 2011
We have investigated the self-assembly behavior of fluorenyl-9-methoxycarbonyl (Fmoc)-FG, Fmoc-GG, and Fmoc-GF and compared it to that of Fmoc-FF using potentiometry, fluorescence and infrared spectroscopy, transmission electron microscopy, wide-angle X ...
Tang, C., Saiani, A., Ulijn, R. V.
core   +4 more sources

3D Printing of Self‐Healing Polymers by Material Extrusion: A Process‐Centric Review of Setups, Parameters, and Applications

Advanced Robotics Research, EarlyView.
This review highlights recent advances in material extrusion 3D printing of self‐healing polymers, focusing on the interplay between material chemistry, rheology, hardware customization, and process optimization. Filament‐ and ink‐based extrusion strategies, multimaterial architectures, and postprocessing approaches are discussed for applications in ...
Antonio Pavone, Gianni Stano, Gianluca Percoco   +2 more
wiley   +1 more source