Results 21 to 30 of about 98,246 (140)
Gels, 2023 Multicomponent hydrogels (HGs) based on ultrashort aromatic peptides have been exploited as biocompatible matrices for tissue engineering applications, the delivery of therapeutic and diagnostic agents, and the development of biosensors.
Sabrina Giordano +9 more
doaj +1 more source
Fmoc-diphenylalanine-based hydrogels as a potential carrier for drug delivery
e-Polymers, 2020 High concentrations of IDM drugs can be incorporated into hydrogels during the self-assembly of Fmoc-FF. Small amounts of PAMAM added to the hydrogel (Fmoc-FF 0.5%–IDM 0.5%–PAMAM 0.03%) resulted in more prolonged IDM release when compared with Fmoc-FF 0 ...
Choe Ranjoo, Il Yun Seok
doaj +1 more source
Revisiting the Self-Assembly of Highly Aromatic Phenylalanine Homopeptides
Molecules, 2020 Diphenylalanine peptide (FF), which self-assembles into rigid tubular nanostructures, is a very short core recognition motif in Alzheimer’s disease β-amyloid (Aβ) polypeptide.
Enric Mayans, Carlos Alemán
doaj +1 more source
Fmoc-Diphenylalanine Hydrogels: Optimization of Preparation Methods and Structural Insights
Pharmaceuticals, 2022 Hydrogels (HGs) are tri-dimensional materials with a non-Newtonian flow behaviour formed by networks able to encapsulate high amounts of water or other biological fluids.
Carlo Diaferia +3 more
doaj +1 more source
Peptide-based scaffolds for the culture and maintenance of primary human hepatocytes
Scientific Reports, 2021 We report here the use of a nanofibrous hydrogel as a 3D scaffold for the culture and maintenance of functional primary human hepatocytes. The system is based on the cooperative assembly of a fiber-forming peptide component, fluorenylmethyloxycarbonyl ...
Douglas MacPherson +3 more
doaj +1 more source
Poly(acrylic acid)/Dipeptide Double-Network Hydrogel to Achieve a Highly Stretchable Strain Sensor
Chemosensors, 2022 Flexible and stretchable strain sensors can be applied for human health monitoring and disease diagnoses via the output of multiple biophysical signals. However, it is still a challenge to fabricate short-peptide-based strain sensors. Here, we prepared a
Xin Luo, Boya Ding, Xingcen Liu
doaj +1 more source
Biomedicines, 2021 Peptide-based hydrogels (PHGs) are biocompatible materials suitable for biological, biomedical, and biotechnological applications, such as drug delivery and diagnostic tools for imaging.
Carlo Diaferia +6 more
doaj +1 more source
Supramolecular Degraders: An Emerging Paradigm in Targeted Protein Degradation. [PDF]
Adv Sci (Weinh)Dynamic supramolecular assembly reshapes targeted protein degradation by coordinating modular degrader construction, delivery, functional integration, and intracellular assembly or activation across proteasomal, endosomal–lysosomal, and autophagy–lysosomal pathways.
Liu K +8 more
europepmc +2 more sources
Ultrasound-Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis. [PDF]
Adv Sci (Weinh)We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Li W +9 more
europepmc +2 more sources
, 2009 With a view to repair the degenerated nucleus pulposus (NP) of intervertebral discs, we grew bovine NP cells on fluorenylmethoxycarbonyl-diphenylalanine (Fmoc-FF)/ Fmoc-diglycine (Fmoc-GG) hydrogels. The gels prepared in two different molar ratios of Fmoc-
Helen, W., Gough, J. E., Ulijn, R. V.
core +4 more sources