Results 191 to 200 of about 7,212 (245)

High-intensity training and irisin response: A possible molecular cross-talk for irisin response. [PDF]

Curr Res Physiol
Li P, Tong L, Bi X.
europepmc   +1 more source

Irisin: Emerging Therapeutic Targets for Cognitive Impairment-Related Diseases. [PDF]

Expert Rev Mol Med
Ma M, Jing G, Tian Y, Yin R, Zhang M.
europepmc   +1 more source

Muscle-derived factor alleviated cognitive impairment caused by intestinal ischemia-reperfusion. [PDF]

Redox Biol
Tan Y, Mu G, Wang F, Fan X, Yang C, Shi Z, Bai Y, Xie B, Yu X, Feng J, Jia J, Wang X, Chen Y, Zhou J.   +13 more
europepmc   +1 more source

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Maternal prednisone exposure during pregnancy elevates susceptibility to osteoporosis in female offspring: The role of mitophagy/FNDC5 alteration in skeletal muscle

Journal of Hazardous Materials
Maternal exposure to glucocorticoids has been associated with adverse outcomes in offspring. However, the consequences and mechanisms of gestational exposure to prednisone on susceptibility to osteoporosis in the offspring remain unclear.
Qu-nan, Wang
exaly   +2 more sources

Fndc5 is translated from an upstream ATG start codon and cleaved to produce irisin myokine precursor protein in humans and mice

Cell Metabolism
Witmer et al. provide genomic and molecular evidence to demonstrate that Fndc5 (irisin myokine precursor protein) is translated in humans from an overlooked upstream ATG codon.
N. Witmer, Connor R. Linzer, Ryan L. Boudreau   +2 more
exaly   +2 more sources

Expression of Irisin/FNDC5 in Breast Cancer

International Journal of Molecular Sciences, 2022
Irisin is a myokine formed from fibronectin type III domain-containing protein 5 (FNDC5), which can be found in various cancer tissues. FNDC5 and irisin levels have been poorly studied in the tumor tissues of breast cancer (BC). The aim of this study was to determine the levels of irisin expression in BC tissues and compare them to clinicopathological ...
Kamil Cebulski, Katarzyna Nowińska, Karolina Jablonska   +2 more
exaly   +4 more sources

FNDC5/Irisin protects neurons through Caspase3 and Bax pathways

Cell Biochemistry and Function
Irisin is a glycosylated protein formed from the hydrolysis of fibronectin type III domain‐containing protein 5 (FNDC5). Recent studies have demonstrated that FNDC5/Irisin is involved in the regulation of glucose and lipid metabolism, it can inhibit ...
Qiuxia Zhang, Lin-Jie Zhang, N. Zhao, Sheng-Hui Chang, Li Yang   +4 more
semanticscholar   +3 more sources

FNDC5: A novel player in metabolism and metabolic syndrome

Biochimie, 2019
Half a decade ago, transmembrane protein fibronectin type III domain-containing protein 5 (FNDC5) was found to be cleaved as a novel myokine irisin, which burst into prominence for browning of white adipose tissue during exercise. However, FNDC5, the precursor of irisin, has been paid relatively little attention compared with irisin despite evidence ...
Richard Y Cao, Hongchao Zheng, Jian Yang
exaly   +3 more sources