Results 221 to 230 of about 7,212 (245)

Luteolin alleviates muscle atrophy, mitochondrial dysfunction and abnormal FNDC5 expression in high fat diet-induced obese rats and palmitic acid-treated C2C12 myotubes.

Journal of Nutritional Biochemistry
Obesity is associated with a series of skeletal muscle impairments and dysfunctions, which are characterized by metabolic disturbances and muscle atrophy. Luteolin is a phenolic phytochemical with broad pharmacological activities. The present study aimed
Yiyuan Zhang, Chunyun Luo, Puxin Huang, Yahong Cheng, Yufang Ma, Jiefang Gao, Hong Ding   +6 more
semanticscholar   +1 more source

Effects of Aerobic Exercise and Resistance Training on Cognitive Function: Comparative Study Based on FNDC5/Irisin/BDNF Pathway

Dementia and Geriatric Cognitive Disorders
Introduction: Exercise has been recommended to suppress or prevent cognitive decline. Aerobic exercise (AE) may suppress cognitive decline via the fibronectin type III domain-containing protein 5 (FNDC5)/irisin/brain-derived neurotrophic factor (BDNF ...
Shotaro Izawa, K. Nishii, Naoki Aizu, Takumi Kito, Daiki Iwata, Takeshi Chihara, Hirohide Sawada, Runhong Yao, Kouji Yamada   +8 more
semanticscholar   +1 more source

FNDC5/Irisin System in Neuroinflammation and Neurodegenerative Diseases: Update and Novel Perspective

International Journal of Molecular Sciences, 2021
Maria Teresa Dell'Abate, Giancarlo Logroscino, Silvia Colucci   +2 more
exaly  

FNDC5/Irisin attenuates diabetic cardiomyopathy in a type 2 diabetes mouse model by activation of integrin αV/β5-AKT signaling and reduction of oxidative/nitrosative stress

Journal of Molecular and Cellular Cardiology, 2021
Fuyang Zhang, Guangyu Hu, Hang Zhao
exaly  

Irisin/FNDC5 regulate carbohydrate metabolism in the exocrine pancreas

Pancreatology, 2023
Avital Horwitz, Ruth Birk
openaire   +1 more source

Irisin/FNDC5 time-dependently and acutely regulate pancreatic lipase

Pancreatology, 2023
Avital Horwitz, Ruth Birk
openaire   +1 more source

Fndc5/irisin mediates the benefits of aerobic exercise intervention on aging-associated sarcopenia in mice

European Geriatric Medicine
Yuxia Ma, Yi Liu, Jiachuang Zheng, Zhixia Zheng, Jingjing Li   +4 more
semanticscholar   +1 more source

FNDC5/Irisin exacerbates APAP-induced acute liver injury through activating JNK/NF-κB and inflammatory response

Acta Pharmacologica Sinica
Qian-hui Zhang, Leiming Jin, Mengsha Lin, Min-xiu Wang, Ya-qian Cui, Jiaxi Ye, Yong-qiang Xiong, Wu Luo, Weiwei Zhu, Guang Liang   +9 more
semanticscholar   +1 more source

FNDC5 induces M2 macrophage polarization and promotes hepatocellular carcinoma cell growth by affecting the PPARγ/NF-κB/NLRP3 pathway

Biochemical and Biophysical Research Communications, 2021
Huayuan Liu, Zhipeng Jin, Ting Zhu
exaly  

Keto Acids Attenuate Skeletal Muscle Atrophy in Chronic Kidney Disease via Inhibiting Pyroptosis and Upregulating Irisin Precursor FNDC5 Expression

Calcified Tissue International
Peixin Wang, Qi Pang, Aihua Zhang
semanticscholar   +1 more source