Results 81 to 90 of about 6,156 (251)

Lack of Association Between FNDC5 Gene Polymorphisms, Serum Irisin Levels and Allergic Rhinitis

open access: yesActa Medica Alanya, 2023
Aim: Allergic rhinitis (AR) is an inflammatory nasal mucosa disease caused by type 1 immunoglobulin E-mediated reactions to allergen exposure. Irisin is a hormone released by skeletal muscles in response to exercise.
Hüseyin Günizi, Durkadın Demir Ekşi
doaj   +1 more source

Irisin treatment improves healing of dystrophic skeletal muscle [PDF]

open access: yes, 2017
Background: Irisin is an exercise induced myokine that is shown to promote browning of adipose tissue and hence, increase energy expenditure. Furthermore, our unpublished results indicate that Irisin improves myogenic differentiation and induces skeletal
Ge, Xiaojia   +6 more
core   +2 more sources

تأثیر دویدن روی نوارگردان با شدت کم بر بیان ژن های PGC-1α، FNDC5 و BDNF درهیپوکامپ موش های صحرایی نر [PDF]

open access: yesمطالعات کاربردی علوم زیستی در ورزش, 2019
زمینه و هدف: مطالعات پیشین نشان داده­­ اند که عامل نوروتروفیک مشتق شده از مغز (BDNF) در القاء اثرات مفید فعالیت ورزشی بر مغز به ویژه هیپوکامپ نقش بسیار حیاتی دارد.
سید محمد علی عظیمی دخت   +4 more
doaj   +1 more source

Myostatin signals through miR-34a to regulate Fndc5 expression and browning of white adipocytes [PDF]

open access: yes, 2017
Background/Objectives: Myostatin (Mstn) has a pivotal role in glucose and lipid metabolism. Mstn deficiency leads to the increased browning of white adipose tissue (WAT), which results in the increased energy expenditure and protection against diet ...
Ge, X.   +5 more
core   +1 more source

Exercise-induced myokine FNDC5/irisin functions in cardiovascular protection and intracerebral retrieval of synaptic plasticity

open access: yesCell & Bioscience, 2019
Physical exercise is well known to benefit human health at every age. However, the exact mechanism through which physical exercise improves health remains unknown.
Xin Zhou   +4 more
doaj   +1 more source

FNDC5/irisin ameliorates bone loss of type 1 diabetes by suppressing endoplasmic reticulum stress‑mediated ferroptosis

open access: yesJournal of Orthopaedic Surgery and Research
Background Ferroptosis is known to play a crucial role in diabetic osteopathy. However, key genes and molecular mechanisms remain largely unclear. This study aimed to identify a crucial ferroptosis-related differentially expressed gene (FR-DEG) in ...
Qianqian Dong   +3 more
semanticscholar   +1 more source

The Role of Irisin/FNDC5 Expression and Its Serum Level in Breast Cancer

open access: yesInternational Journal of Molecular Sciences, 2023
Irisin (Ir) is an adipomyokine formed from fibronectin type III domain-containing protein 5 (FNDC5), which can be found in various cancer tissues. Additionally, FNDC5/Ir is suspected of inhibiting the epithelial-mesenchymal transition (EMT) process. This relationship has been poorly studied for breast cancer (BC).
Kamil Cebulski   +11 more
openaire   +2 more sources

Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Fibronectin type III domain-containing 5 (FNDC5) protein is involved in the beneficial effects of exercise on metabolism. FNDC5 attenuates hepatic steatosis induced by high fat diet (HFD).
Bing Zhou   +9 more
doaj   +1 more source

Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse [PDF]

open access: yes, 2015
Background: Obese adults are prone to develop metabolic and cardiovascular diseases. Furthermore, over-weight expectant mothers give birth to large babies who also have increased likelihood of developing metabolic and cardiovascular diseases. Fundamental
A Matsakas   +59 more
core   +2 more sources

Gen verileri üzerinde ilginçlik ölçütleri kullanılarak birliktelik kuralları madenciliğinin uygulanması [PDF]

open access: yes, 2022
Aim: Data mining is the discovery process of beneficial information, not revealed from large-scale data beforehand. One of the fields in which data mining is widely used is health.
Ahmet Kadir ARSLAN   +6 more
core   +1 more source

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